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Academic Journal

Lyso-Gb3 activates Notch1 in human podocytes.

  • Authors : Sanchez-Niño MD; IIS-Fundacion Jimenez Diaz, School of Medicine, UAM, Madrid, Spain, IRSIN, Madrid, Spain, REDINREN, Madrid, Spain and.; Carpio D

Subjects: Signal Transduction*; Glycolipids/Glycolipids/Glycolipids/*pharmacology ; Podocytes/Podocytes/Podocytes/*metabolism

  • Source: Human molecular genetics [Hum Mol Genet] 2015 Oct 15; Vol. 24 (20), pp. 5720-32. Date of Electronic Publication: 2015 Jul 23.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model:

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Academic Journal

Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer.

  • Authors : Rafnar T; deCODE Genetics/AMGEN, Reykjavik 101, Iceland .; Sulem P

Subjects: Calcium-Binding Proteins/Calcium-Binding Proteins/Calcium-Binding Proteins/*genetics ; Chromosomes, Human, Pair 20/Chromosomes, Human, Pair 20/Chromosomes, Human, Pair 20/*genetics ; Intercellular Signaling Peptides and Proteins/Intercellular Signaling Peptides and Proteins/Intercellular Signaling Peptides and Proteins/*genetics

  • Source: Human molecular genetics [Hum Mol Genet] 2014 Oct 15; Vol. 23 (20), pp. 5545-57. Date of Electronic Publication: 2014 May 26.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model:

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Academic Journal

Histone demethylase KDM4C regulates sphere formation by mediating the cross talk between Wnt and Notch pathways in colonic cancer cells.

  • Authors : Yamamoto S; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.; Tateishi K

Subjects: Signal Transduction*; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*genetics ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*metabolism

  • Source: Carcinogenesis [Carcinogenesis] 2013 Oct; Vol. 34 (10), pp. 2380-8. Date of Electronic Publication: 2013 May 22.Publisher: Irl Press At Oxford University Press Country of Publication: England NLM ID: 8008055 Publication Model:

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Academic Journal

The putative tumor suppressor miR-524-5p directly targets Jagged-1 and Hes-1 in glioma.

  • Authors : Chen L; Department of Neurosurgery, Tianjin Medical University General Hospital, Laboratory of Neuro-Oncology, Tianjin Neurological Institute, Tianjin 300052, China.; Zhang W

Subjects: Genes, Tumor Suppressor*; Basic Helix-Loop-Helix Transcription Factors/Basic Helix-Loop-Helix Transcription Factors/Basic Helix-Loop-Helix Transcription Factors/*metabolism ; Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*metabolism

  • Source: Carcinogenesis [Carcinogenesis] 2012 Nov; Vol. 33 (11), pp. 2276-82. Date of Electronic Publication: 2012 Aug 07.Publisher: Irl Press At Oxford University Press Country of Publication: England NLM ID: 8008055 Publication Model:

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Academic Journal

miRNA-34c regulates Notch signaling during bone development.

  • Authors : Bae Y; Department of Molecular and Human Genetics, Baylor College of Medicine,One Baylor Plaza, Houston, TX 77030, USA.; Yang T

Subjects: Osteogenesis* ; Signal Transduction*; Calcium-Binding Proteins/Calcium-Binding Proteins/Calcium-Binding Proteins/*metabolism

  • Source: Human molecular genetics [Hum Mol Genet] 2012 Jul 01; Vol. 21 (13), pp. 2991-3000. Date of Electronic Publication: 2012 Apr 12.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model:

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Academic Journal

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

  • Authors : Humphreys R; Department of Surgery, Vanderbilt Medical Center, Nashville, TN 37232, USA.; Zheng W

Subjects: Alagille Syndrome/Alagille Syndrome/Alagille Syndrome/*physiopathology ; Calcium-Binding Proteins/Calcium-Binding Proteins/Calcium-Binding Proteins/*physiology ; Craniofacial Abnormalities/Craniofacial Abnormalities/Craniofacial Abnormalities/*etiology

  • Source: Human molecular genetics [Hum Mol Genet] 2012 Mar 15; Vol. 21 (6), pp. 1374-83. Date of Electronic Publication: 2011 Dec 08.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model:

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Academic Journal

MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells.

  • Authors : Pang RT; Department of Obstetrics and Gynaecology, The University of Hong Kong, Pokfulam Road, Hong Kong, People's Republic of China.; Leung CO

Subjects: Down-Regulation* ; Neoplasm Invasiveness*; Calcium-Binding Proteins/Calcium-Binding Proteins/Calcium-Binding Proteins/*genetics

  • Source: Carcinogenesis [Carcinogenesis] 2010 Jun; Vol. 31 (6), pp. 1037-44. Date of Electronic Publication: 2010 Mar 29.Publisher: Irl Press At Oxford University Press Country of Publication: England NLM ID: 8008055 Publication Model:

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Academic Journal

NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling.

  • Authors : McBride KL; Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.; Riley MF

Subjects: Mutation, Missense* ; Signal Transduction*; Calcium-Binding Proteins/Calcium-Binding Proteins/Calcium-Binding Proteins/*metabolism

  • Source: Human molecular genetics [Hum Mol Genet] 2008 Sep 15; Vol. 17 (18), pp. 2886-93. Date of Electronic Publication: 2008 Jun 30.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model:

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Academic Journal

Biological function of mutant forms of JAGGED1 proteins in Alagille syndrome: inhibitory effect on Notch signaling.

Subjects: Signal Transduction*; Alagille Syndrome/Alagille Syndrome/Alagille Syndrome/*metabolism ; Calcium-Binding Proteins/Calcium-Binding Proteins/Calcium-Binding Proteins/*physiology

  • Source: Human molecular genetics [Hum Mol Genet] 2007 Nov 15; Vol. 16 (22), pp. 2683-92. Date of Electronic Publication: 2007 Aug 24.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model:

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Academic Journal

The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti.

  • Authors : Tsai H; MRC Mammalian Genetics Unit and Mouse Genome Centre, Harwell, Oxon OX11 ORD, UK.; Hardisty RE

Subjects: Body Patterning*; Membrane Proteins/Membrane Proteins/Membrane Proteins/*genetics ; Organ of Corti/Organ of Corti/Organ of Corti/*embryology

  • Source: Human molecular genetics [Hum Mol Genet] 2001 Mar 01; Vol. 10 (5), pp. 507-12.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print

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