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Academic Journal

Ginkgetin improved experimental colitis by inhibiting intestinal epithelial cell apoptosis through EGFR/PI3K/AKT signaling.

  • Authors : Geng Z; Department of Central Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, China.; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-related Diseases, Bengbu, Anhui, China.

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Colitis*/Colitis*/Colitis*/chemically induced

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Jul 31; Vol. 38 (14), pp. e23817.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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Academic Journal

DNAJC24 acts directly with PCNA and promotes malignant progression of LUAD by activating phosphorylation of AKT.

  • Authors : Liu D; Department of Hepatobiliary Cancer, Liver Cancer Research Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.; National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.

Subjects: Cell Proliferation* ; HSP40 Heat-Shock Proteins*/HSP40 Heat-Shock Proteins*/HSP40 Heat-Shock Proteins*/metabolism ; HSP40 Heat-Shock Proteins*/HSP40 Heat-Shock Proteins*/HSP40 Heat-Shock Proteins*/genetics

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 May 15; Vol. 38 (9), pp. e23630.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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Academic Journal

Chaperone-mediated autophagy protects the bone formation from excessive inflammation through PI3K/AKT/GSK3β/β-catenin pathway.

  • Authors : Hang K; Department of Orthopaedics, the Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Zhejiang, Hangzhou, China.; Wang Y

Subjects: Osteogenesis*/Osteogenesis*/Osteogenesis*/physiology ; Glycogen Synthase Kinase 3 beta*/Glycogen Synthase Kinase 3 beta*/Glycogen Synthase Kinase 3 beta*/metabolism ; Glycogen Synthase Kinase 3 beta*/Glycogen Synthase Kinase 3 beta*/Glycogen Synthase Kinase 3 beta*/genetics

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 May 31; Vol. 38 (10), pp. e23646.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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Academic Journal

mTORC2-AKT signaling to PFKFB2 activates glycolysis that enhances stemness and tumorigenicity of intestinal epithelial cells.

  • Authors : Li M; Tianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.; State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.

Subjects: Neoplasms* ; Proto-Oncogene Proteins c-akt*; Animals

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Mar 15; Vol. 38 (5), pp. e23532.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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Academic Journal

Epidermal ET-1 signal induces activation of resting hair follicles by upregulating the PI3K/AKT pathway in the dermis.

  • Authors : Gao Y; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.; Department of Anesthesiology, The First People's Hospital of Foshan, Foshan, China.

Subjects: Hair Follicle*/Hair Follicle*/Hair Follicle*/metabolism ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism; Animals

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Feb 29; Vol. 38 (4), pp. e23476.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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Academic Journal

Histone deacetylase 6 deficiency protects the liver against ischemia/reperfusion injury by activating PI3K/AKT/mTOR signaling.

  • Authors : Pan J; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Translational Medical Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Reperfusion Injury*/Reperfusion Injury*/Reperfusion Injury*/metabolism; Animals

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Feb 29; Vol. 38 (4), pp. e23477.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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Academic Journal

Kinesin light chain 1 stabilizes insulin receptor substrate 1 to regulate the IGF-1-AKT signaling pathway during myoblast differentiation.

  • Authors : Qu Z; Department of Orthopaedic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.; Shi L

Subjects: Insulin-Like Growth Factor I* ; Proto-Oncogene Proteins c-akt*; Animals

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Feb 15; Vol. 38 (3), pp. e23432.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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Academic Journal

IGF-I protects porcine granulosa cells from hypoxia-induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway.

  • Authors : Liu Z; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.; Feng C

Subjects: Recombinational DNA Repair* ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism; Female

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Jan; Vol. 38 (1), pp. e23332.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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Academic Journal

Nur77 is involved in the regulation of obesity-related lower muscle mass by promoting Pten degradation.

  • Authors : Chen F; Department of Gerontology, Shengjing Hospital of China Medical University, Shenyang, China.; Yu Y

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/metabolism; Humans

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2023 Aug; Vol. 37 (8), pp. e23083.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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Academic Journal

Peptide RL-QN15 promotes regeneration of epidermal nerve fibers and recovery of sensory function in diabetic skin wounds.

  • Authors : Wu Y; Department of Anatomy and Histology & Embryology, Faculty of Basic Medical Science, Kunming Medical University, 650500, Yunnan, Kunming, China.; Wang Y

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Diabetes Mellitus, Experimental*; Rats

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2023 Apr; Vol. 37 (4), pp. e22892.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484

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