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Academic Journal

TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT.

  • Authors : de Nonneville A; Marseille Cancer Research Centre (CRCM), Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Team « Telomere and Chromatin ». Equipe labellisée Ligue Nationale Contre Le Cancer, Aix-Marseille Univ, Marseille, France.; Cancer Research Unit, Faculty of Medicine and Health, Children's Medical Research Institute, University of Sydney, Westmead, NSW, Australia.

Subjects: DNA Topoisomerases, Type I*/DNA Topoisomerases, Type I*/DNA Topoisomerases, Type I*/genetics ; Osteosarcoma*/Osteosarcoma*/Osteosarcoma*/genetics ; X-linked Nuclear Protein*/X-linked Nuclear Protein*/X-linked Nuclear Protein*/genetics

  • Source: EMBO molecular medicine [EMBO Mol Med] 2022 Oct 10; Vol. 14 (10), pp. e15859. Date of Electronic Publication: 2022 Aug 03.Publisher: EMBO Press Country of Publication: England NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib.

  • Authors : Kobialka P; Endothelial Pathobiology and Microenvironment, Josep Carreras Leukaemia Research Institute, Barcelona, Spain.; Sabata H

Subjects: Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/genetics ; Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/metabolism ; Vascular Malformations*/Vascular Malformations*/Vascular Malformations*/genetics

  • Source: EMBO molecular medicine [EMBO Mol Med] 2022 Jul 07; Vol. 14 (7), pp. e15619. Date of Electronic Publication: 2022 Jun 13.Publisher: EMBO Press Country of Publication: England NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections.

  • Authors : Maehara K; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.; Tomimatsu K

Subjects: Epigenome* ; Epigenomics*; Genome

  • Source: Molecular systems biology [Mol Syst Biol] 2021 Nov; Vol. 17 (11), pp. e10323.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print Cited Medium: Internet

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Academic Journal

Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19.

  • Authors : Theobald SJ; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.

Subjects: COVID-19* ; Spike Glycoprotein, Coronavirus*; Humans

  • Source: EMBO molecular medicine [EMBO Mol Med] 2021 Aug 09; Vol. 13 (8), pp. e14150. Date of Electronic Publication: 2021 Jun 16.Publisher: EMBO Press Country of Publication: England NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects.

  • Authors : Sadek J; Department of Biochemistry, McGill University, Montreal, QC, Canada.; Rosalind & Morris Goodman Cancer Research Center, McGill University, Montreal, QC, Canada.

Subjects: Cachexia* ; Neoplasms*; Animals

  • Source: EMBO molecular medicine [EMBO Mol Med] 2021 Jul 07; Vol. 13 (7), pp. e13591. Date of Electronic Publication: 2021 Jun 07.Publisher: EMBO Press Country of Publication: England NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

CXCR4 engagement triggers CD47 internalization and antitumor immunization in a mouse model of mesothelioma.

  • Authors : Mezzapelle R; Chromatin Dynamics Unit, Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.

Subjects: CD47 Antigen* ; Mesothelioma*/Mesothelioma*/Mesothelioma*/immunology ; Mesothelioma*/Mesothelioma*/Mesothelioma*/metabolism

  • Source: EMBO molecular medicine [EMBO Mol Med] 2021 Jun 07; Vol. 13 (6), pp. e12344. Date of Electronic Publication: 2021 May 06.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks.

  • Authors : Mallm JP; Division of Chromatin Networks, German Cancer Research Center (DKFZ) and Bioquant, Heidelberg, Germany.; Iskar M

Subjects: Gene Expression Regulation, Leukemic* ; Gene Regulatory Networks*; Chromatin/Chromatin/Chromatin/*chemistry

  • Source: Molecular systems biology [Mol Syst Biol] 2019 May 22; Vol. 15 (5), pp. e8339. Date of Electronic Publication: 2019 May 22.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Electronic Cited Medium:

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Academic Journal

RNA polymerase II primes Polycomb-repressed developmental genes throughout terminal neuronal differentiation.

  • Authors : Ferrai C; Epigenetic Regulation and Chromatin Architecture, Max Delbrück Center for Molecular Medicine, Berlin, Germany .; Genome Function, MRC London Institute of Medical Sciences (previously MRC Clinical Sciences Centre), London, UK.

Subjects: Genes, Developmental*; Dopaminergic Neurons/Dopaminergic Neurons/Dopaminergic Neurons/*cytology ; Mouse Embryonic Stem Cells/Mouse Embryonic Stem Cells/Mouse Embryonic Stem Cells/*cytology

  • Source: Molecular systems biology [Mol Syst Biol] 2017 Oct 16; Vol. 13 (10), pp. 946. Date of Electronic Publication: 2017 Oct 16.Publisher: EMBO Press Country of Publication: England NLM ID: 101235389 Publication Model: Electronic Cited Medium:

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Academic Journal

Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts.

  • Authors : Bian B; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Parc Scientifique et Technologique de Luminy, Aix-Marseille Université and Institut Paoli-Calmettes, Marseille, France.; Bigonnet M

Subjects: Gene Expression Profiling* ; Heterografts*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*metabolism

  • Source: EMBO molecular medicine [EMBO Mol Med] 2017 Apr; Vol. 9 (4), pp. 482-497.Publisher: EMBO Press Country of Publication: England NLM ID: 101487380 Publication Model: Print Cited Medium: Internet

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Academic Journal

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation.

Subjects: Transcription, Genetic*; Chromatin/Chromatin/Chromatin/*chemistry ; Chromosomes/Chromosomes/Chromosomes/*chemistry

  • Source: Molecular systems biology [Mol Syst Biol] 2015 Dec 23; Vol. 11 (12), pp. 852. Date of Electronic Publication: 2015 Dec 23.Publisher: EMBO Press Country of Publication: England NLM ID: 101235389 Publication Model: Electronic Cited Medium:

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