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Academic Journal

Local cannabinoid receptor type-1 regulates glial cell activity and insulin-like growth factor-1 receptor signaling in the mediobasal hypothalamus.

  • Authors : Palmisano M; Institute of Molecular Psychiatry, Medical Faculty, University Clinics of Bonn, Bonn 53125, Germany.; Ramunno CF

Subjects: Receptor, Cannabinoid, CB1*/Receptor, Cannabinoid, CB1*/Receptor, Cannabinoid, CB1*/metabolism ; Receptor, Cannabinoid, CB1*/Receptor, Cannabinoid, CB1*/Receptor, Cannabinoid, CB1*/genetics ; Receptor, IGF Type 1*/Receptor, IGF Type 1*/Receptor, IGF Type 1*/metabolism

  • Source: Mechanisms of ageing and development [Mech Ageing Dev] 2024 Aug; Vol. 220, pp. 111954. Date of Electronic Publication: 2024 May 29.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 0347227 Publication Model: Print-Electronic Cited

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Academic Journal

RETRACTED: IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas.

  • Authors : Mihajluk K; Brain Tumour Research Centre, Institute of Biomedical and Biomolecular Sciences, IBBS, University of Portsmouth, PO1 2DT, UK.; Simms C

Subjects: Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*pharmacology ; Aspirin/Aspirin/Aspirin/*administration & dosage ; Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*drug therapy

  • Source: Cancer letters [Cancer Lett] 2019 Aug 28; Vol. 458, pp. 29-38. Date of Electronic Publication: 2019 May 23.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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Academic Journal

IGF1R/IRS1 targeting has cytotoxic activity and inhibits PI3K/AKT/mTOR and MAPK signaling in acute lymphoblastic leukemia cells.

  • Authors : Rodrigues Alves APN; Department of Internal Medicine, University of Sao Paulo at Ribeirao Preto Medical School, Ribeirao Preto, Brazil.; Fernandes JC

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Imidazoles/Imidazoles/Imidazoles/*pharmacology ; Insulin Receptor Substrate Proteins/Insulin Receptor Substrate Proteins/Insulin Receptor Substrate Proteins/*antagonists & inhibitors

  • Source: Cancer letters [Cancer Lett] 2019 Aug 01; Vol. 456, pp. 59-68. Date of Electronic Publication: 2019 Apr 28.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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Academic Journal

Simultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death.

  • Authors : Oberthür R; Institute of Human Genetics, University Medical Centre Göttingen, Germany.; Seemann H

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*drug therapy ; DNA Repair/DNA Repair/DNA Repair/*drug effects

  • Source: Cancer letters [Cancer Lett] 2017 Oct 28; Vol. 407, pp. 93-105. Date of Electronic Publication: 2017 Aug 18.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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Academic Journal

The cytoskeleton actin binding protein filamin A impairs both IGF2 mitogenic effects and the efficacy of IGF1R inhibitors in adrenocortical cancer cells.

  • Authors : Catalano R; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy; PhD Program in Endocrinological Sciences, Sapienza University of Rome, Rome, Italy.

Subjects: Adrenal Cortex Neoplasms/Adrenal Cortex Neoplasms/Adrenal Cortex Neoplasms/*pathology ; Adrenocortical Carcinoma/Adrenocortical Carcinoma/Adrenocortical Carcinoma/*pathology ; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism

  • Source: Cancer letters [Cancer Lett] 2021 Jan 28; Vol. 497, pp. 77-88. Date of Electronic Publication: 2020 Oct 16.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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Academic Journal

Insulin-like growth factor-1 receptor induces immunosuppression in lung cancer by upregulating B7-H4 expression through the MEK/ERK signaling pathway.

  • Authors : Zhao Z; College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.; Zhang N

Subjects: Immune Tolerance*; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*immunology ; MAP Kinase Signaling System/MAP Kinase Signaling System/MAP Kinase Signaling System/*physiology

  • Source: Cancer letters [Cancer Lett] 2020 Aug 10; Vol. 485, pp. 14-26. Date of Electronic Publication: 2020 May 14.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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Academic Journal

The insulin-like growth factor (IGF) axis as an anticancer target in prostate cancer.

  • Authors : Heidegger I; Division of Experimental Urology, Department of Urology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria.; Massoner P

Subjects: Drug Design* ; Molecular Targeted Therapy*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use

  • Source: Cancer letters [Cancer Lett] 2015 Oct 28; Vol. 367 (2), pp. 113-21. Date of Electronic Publication: 2015 Jul 29.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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Academic Journal

Activation of insulin-like growth factor receptor signaling mediates resistance to histone deacetylase inhibitors.

  • Authors : Kim JS; Department of Thoracic Head & Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, United States.; Lee SC

Subjects: Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/*pharmacology ; Receptor, IGF Type 1/Receptor, IGF Type 1/Receptor, IGF Type 1/*metabolism; Animals

  • Source: Cancer letters [Cancer Lett] 2015 Jun 01; Vol. 361 (2), pp. 197-206. Date of Electronic Publication: 2015 Feb 23.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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Academic Journal

SUMOylation of insulin-like growth factor 1 receptor, promotes proliferation in acute myeloid leukemia.

  • Authors : Zhang J; Department of Hematology, Xiang-Ya Hospital, Central South University, 87 Xiang-Ya Road, Changsha 410008, China.; Huang FF

Subjects: Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/*metabolism ; Receptor, IGF Type 1/Receptor, IGF Type 1/Receptor, IGF Type 1/*metabolism; Adult

  • Source: Cancer letters [Cancer Lett] 2015 Feb 01; Vol. 357 (1), pp. 297-306. Date of Electronic Publication: 2014 Nov 28.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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Academic Journal

IGF-1R inhibition potentiates cytotoxic effects of chemotherapeutic agents in early stages of chemoresistant ovarian cancer cells.

  • Authors : Singh RK; Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, Maharashtra, India.; Gaikwad SM

Subjects: Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*pharmacology ; Cisplatin/Cisplatin/Cisplatin/*pharmacology ; Neoplasms, Glandular and Epithelial/Neoplasms, Glandular and Epithelial/Neoplasms, Glandular and Epithelial/*drug therapy

  • Source: Cancer letters [Cancer Lett] 2014 Nov 28; Vol. 354 (2), pp. 254-62. Date of Electronic Publication: 2014 Aug 23.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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  • 1-10 of  47 results for ""Receptor, IGF Type 1""