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Academic Journal

RBM5 induces motor neuron apoptosis in hSOD1 G93A -related amyotrophic lateral sclerosis by inhibiting Rac1/AKT pathways.

  • Authors : Tan X; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin 150000, China.; Su X

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/metabolism ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/pathology

  • Source: Brain research bulletin [Brain Res Bull] 2024 Oct 01; Vol. 216, pp. 111049. Date of Electronic Publication: 2024 Aug 12.Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605818 Publication Model: Print-Electronic Cited

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Academic Journal

Rac1 as a therapeutic anticancer target: Promises and limitations.

  • Authors : Bailly C; OncoWitan, Scientific Consulting Office, Lille (Wasquehal), 59290, France. Electronic address: .; Beignet J

Subjects: Oxidative Stress* ; rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/genetics ; rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/metabolism

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2022 Sep; Vol. 203, pp. 115180. Date of Electronic Publication: 2022 Jul 16.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Butyrate-containing structured lipids inhibit RAC1 and epithelial-to-mesenchymal transition markers: a chemopreventive mechanism against hepatocarcinogenesis.

  • Authors : de Conti A; Division of Biochemical Toxicology, FDA-National Center for Toxicological Research, Jefferson, AR, USA.; Tryndyak V

Subjects: Epithelial-Mesenchymal Transition*; Butyrates/Butyrates/Butyrates/*pharmacology ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*prevention & control

  • Source: The Journal of nutritional biochemistry [J Nutr Biochem] 2020 Dec; Vol. 86, pp. 108496. Date of Electronic Publication: 2020 Sep 11.Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited

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Academic Journal

Distinct contribution of Rac1 expression in cardiomyocytes to anthracycline-induced cardiac injury.

  • Authors : Henninger C; Institute of Toxicology, Medical Faculty, Heinrich-Heine University Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.; Pohlmann S

Subjects: Anthracyclines/Anthracyclines/Anthracyclines/*toxicity ; Heart Diseases/Heart Diseases/Heart Diseases/*chemically induced ; Heart Diseases/Heart Diseases/Heart Diseases/*metabolism

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2019 Jun; Vol. 164, pp. 82-93. Date of Electronic Publication: 2019 Mar 29.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Conversion of NOX2 into a constitutive enzyme in vitro and in living cells, after its binding with a chimera of the regulatory subunits.

  • Authors : Masoud R; Laboratoire de Chimie Physique, UMR8000, Université Paris Sud, CNRS, Université Paris Saclay, 91405 Orsay, France.; Serfaty X

Subjects: Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; NADPH Oxidases/NADPH Oxidases/NADPH Oxidases/*metabolism ; Phosphoproteins/Phosphoproteins/Phosphoproteins/*metabolism

  • Source: Free radical biology & medicine [Free Radic Biol Med] 2017 Dec; Vol. 113, pp. 470-477. Date of Electronic Publication: 2017 Oct 25.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited

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Academic Journal

Contribution of guanine nucleotide exchange factor Vav2 to NLRP3 inflammasome activation in mouse podocytes during hyperhomocysteinemia.

  • Authors : Conley SM; Department of Pharmacology & Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298, USA.; Abais-Battad JM

Subjects: Hyperhomocysteinemia/Hyperhomocysteinemia/Hyperhomocysteinemia/*genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/NLR Family, Pyrin Domain-Containing 3 Protein/NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism ; Neuropeptides/Neuropeptides/Neuropeptides/*metabolism

  • Source: Free radical biology & medicine [Free Radic Biol Med] 2017 May; Vol. 106, pp. 236-244. Date of Electronic Publication: 2017 Feb 11.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited

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Academic Journal

Hepatoprotective effects of curcumin in rats after bile duct ligation via downregulation of Rac1 and NOX1.

  • Authors : Ghoreshi ZA; Department of Biochemistry, School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.; Kabirifar R

Subjects: Curcumin/Curcumin/Curcumin/*pharmacology ; Liver/Liver/Liver/*drug effects ; Liver Diseases/Liver Diseases/Liver Diseases/*drug therapy

  • Source: Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition] 2017 Apr; Vol. 36, pp. 72-78. Date of Electronic Publication: 2016 Jul 01.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8802712 Publication Model: Print-Electronic Cited

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Academic Journal

Identification, characterization and immunological analysis of Ras related C3 botulinum toxin substrate 1 (Rac1) from grass carp Ctenopharyngodon idella.

  • Authors : Hu MY; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Shanghai Ocean University, Ministry of Education, Shanghai, 201306, PR China.; Shen YB

Subjects: Carps/Carps/Carps/*genetics ; Carps/Carps/Carps/*immunology ; Fish Proteins/Fish Proteins/Fish Proteins/*genetics

  • Source: Developmental and comparative immunology [Dev Comp Immunol] 2016 Jan; Vol. 54 (1), pp. 20-31. Date of Electronic Publication: 2015 Aug 24.Publisher: Elsevier Science Country of Publication: United States NLM ID: 7708205 Publication Model: Print-Electronic Cited

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Academic Journal

Potential roles of PP2A-Rac1 signaling axis in pancreatic β-cell dysfunction under metabolic stress: Progress and promise.

  • Authors : Kowluru A; Biomedical Laboratory Research Service, John D. Dingell VA Medical Center and Departments of Pharmaceutical Sciences and Internal Medicine, Wayne State University, Detroit, MI 48201, USA. Electronic address: .

Subjects: Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/drug effects; Insulin-Secreting Cells/Insulin-Secreting Cells/Insulin-Secreting Cells/*metabolism ; Protein Phosphatase 2/Protein Phosphatase 2/Protein Phosphatase 2/*metabolism

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2020 Oct; Vol. 180, pp. 114138. Date of Electronic Publication: 2020 Jul 04.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

ASIC1a promotes synovial invasion of rheumatoid arthritis via Ca 2+ /Rac1 pathway.

  • Authors : Niu R; Anhui Key Laboratory of Bioactivity of Natural Products, School of Pharmacy, Anhui Medical University, Hefei 230032, China; The Key Laboratory of Anti-inflammatory and Immune Medicine, Anhui Medical University, Ministry of Education, Hefei 230032, China.

Subjects: Acid Sensing Ion Channels/Acid Sensing Ion Channels/Acid Sensing Ion Channels/*metabolism ; Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*metabolism ; Synoviocytes/Synoviocytes/Synoviocytes/*metabolism

  • Source: International immunopharmacology [Int Immunopharmacol] 2020 Feb; Vol. 79, pp. 106089. Date of Electronic Publication: 2019 Dec 19.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited

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  • 1-10 of  99 results for ""rac1 GTP-Binding Protein""