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Academic Journal

The activation of the HIF-1α-VEGFA-Notch1 signaling pathway by Hydroxysafflor yellow A promotes angiogenesis and reduces myocardial ischemia-reperfusion injury.

  • Authors : Ge C; Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Anhui University of Chinese Medicine, Hefei 230012, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Anhui University of Chinese Medicine, Hefei 230012, China

Subjects: Chalcone*/Chalcone*/Chalcone*/analogs & derivatives ; Chalcone*/Chalcone*/Chalcone*/pharmacology ; Chalcone*/Chalcone*/Chalcone*/therapeutic use

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Dec 05; Vol. 142 (Pt A), pp. 113097. Date of Electronic Publication: 2024 Sep 10.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited

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Academic Journal

Discovery of a new dihydroeugenol-chalcone hybrid with cytotoxic and anti-migratory potential: A dual-action hit for cancer therapeutics.

  • Authors : Nakao IA; School of Pharmacy - Federal University of Ouro Preto, 35400-000 Ouro Preto, MG, Brazil.; Almeida TC

Subjects: Chalcone*/Chalcone*/Chalcone*/pharmacology ; Chalcone*/Chalcone*/Chalcone*/chemistry ; Chalcones*/Chalcones*/Chalcones*/pharmacology

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Dec 15; Vol. 96, pp. 117516. Date of Electronic Publication: 2023 Nov 03.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Furan based synthetic chalcone derivative functions against gut inflammation and oxidative stress demonstrated in in-vivo zebrafish model.

  • Authors : Nayak SPRR; Toxicology and Pharmacology Laboratory, Department of Biotechnology, Faculty of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, 603203, Chengalpattu District, Tamil Nadu, India.; Dhivya LS

Subjects: Colitis*/Colitis*/Colitis*/chemically induced ; Colitis*/Colitis*/Colitis*/drug therapy ; Colitis*/Colitis*/Colitis*/pathology

  • Source: European journal of pharmacology [Eur J Pharmacol] 2023 Oct 15; Vol. 957, pp. 175994. Date of Electronic Publication: 2023 Aug 23.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited

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Academic Journal

A novel chalcone derivative exerts anticancer effects by promoting apoptotic cell death of human pancreatic cancer cells.

  • Authors : Baek S; Research & Development Center, UMUST R&D Corporation, Seoul 01411, South Korea.; Nah S

Subjects: Chalcones*/Chalcones*/Chalcones*/pharmacology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Chalcone*/Chalcone*/Chalcone*/pharmacology

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Oct 01; Vol. 93, pp. 117458. Date of Electronic Publication: 2023 Aug 23.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases.

  • Authors : Shen X; TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Chen H

Subjects: Chalcones*/Chalcones*/Chalcones*/pharmacology ; Chalcones*/Chalcones*/Chalcones*/therapeutic use ; Chalcone*/Chalcone*/Chalcone*/therapeutic use

  • Source: European journal of pharmacology [Eur J Pharmacol] 2023 Sep 05; Vol. 954, pp. 175840. Date of Electronic Publication: 2023 Jun 09.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited

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Academic Journal

Hesperidin Methyl Chalcone reduces extracellular Aβ (25-35) peptide aggregation and fibrillation and also protects Neuro 2a cells from Aβ (25-35) induced neuronal dysfunction.

  • Authors : Jafni S; Department of Biotechnology, Alagappa University, Karaikudi 630003, Tamil Nadu, India.; Sathya S

Subjects: Chalcones*/Chalcones*/Chalcones*/pharmacology ; Hesperidin*/Hesperidin*/Hesperidin*/pharmacology ; Neuroprotective Agents*/Neuroprotective Agents*/Neuroprotective Agents*/pharmacology

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Dec 15; Vol. 96, pp. 117536. Date of Electronic Publication: 2023 Nov 18.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Design, synthesis and biological evaluation of novel chalcone-like compounds as potent and reversible pancreatic lipase inhibitors.

  • Authors : Huo PC; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Subjects: Drug Design*; Chalcone/Chalcone/Chalcone/*pharmacology ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2021 Jan 01; Vol. 29, pp. 115853. Date of Electronic Publication: 2020 Nov 09.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Structure based modification of chalcone analogue activates Nrf2 in the human retinal pigment epithelial cell line ARPE-19.

  • Authors : Cui Y; Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.; Li Y

Subjects: Chalcone* ; Chalcones*/Chalcones*/Chalcones*/pharmacology; Epithelial Cells/Epithelial Cells/Epithelial Cells/metabolism

  • Source: Free radical biology & medicine [Free Radic Biol Med] 2020 Feb 20; Vol. 148, pp. 52-59. Date of Electronic Publication: 2019 Dec 27.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited

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Academic Journal

The plant-derived chalcone Xanthoangelol targets the membrane of Gram-positive bacteria.

  • Authors : Meier D; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany.; Hernández MV

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacology ; Chalcone/Chalcone/Chalcone/*analogs & derivatives ; Gram-Positive Bacteria/Gram-Positive Bacteria/Gram-Positive Bacteria/*drug effects

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2019 Dec 01; Vol. 27 (23), pp. 115151. Date of Electronic Publication: 2019 Oct 15.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Synthesis and biological evaluation of novel synthetic chalcone derivatives as anti-tumor agents targeting Cat L and Cat K.

  • Authors : Wang Y; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.; Xue S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cathepsin K/Cathepsin K/Cathepsin K/*antagonists & inhibitors ; Cathepsin L/Cathepsin L/Cathepsin L/*antagonists & inhibitors

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2018 Jan 01; Vol. 26 (1), pp. 8-16. Date of Electronic Publication: 2017 Sep 18.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium:

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  • 1-10 of  579 results for ""Chalcone""