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Publisher : elsevier inc. on behalf of american society for biochemistry and molecular biology
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Academic Journal

RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.

  • Authors : Kukimoto-Niino M; Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Kanagawa, Japan. Electronic address: .; Katsura K

Subjects: Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/metabolism ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/chemistry ; Guanine Nucleotide Exchange Factors*/Guanine Nucleotide Exchange Factors*/Guanine Nucleotide Exchange Factors*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jul; Vol. 300 (7), pp. 107459. Date of Electronic Publication: 2024 Jun 08.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Cell aggregation activates small GTPase Rac1 and induces CD44 cleavage by maintaining lipid raft integrity.

  • Authors : Li D; Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.; Park Y

Subjects: Membrane Microdomains*/Membrane Microdomains*/Membrane Microdomains*/metabolism ; Monomeric GTP-Binding Proteins*/Monomeric GTP-Binding Proteins*/Monomeric GTP-Binding Proteins*/metabolism ; Hyaluronan Receptors*/Hyaluronan Receptors*/Hyaluronan Receptors*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2023 Dec; Vol. 299 (12), pp. 105377. Date of Electronic Publication: 2023 Oct 20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

PKCα-mediated phosphorylation of the diacylglycerol kinase ζ MARCKS domain switches cell migration modes by regulating interactions with Rac1 and RhoA.

  • Authors : Ard R; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada; Centre for Neuromuscular Disease, University of Ottawa, Ottawa, Ontario, Canada.

Subjects: Cell Movement*; Diacylglycerol Kinase/Diacylglycerol Kinase/Diacylglycerol Kinase/*physiology ; Dystrophin-Associated Proteins/Dystrophin-Associated Proteins/Dystrophin-Associated Proteins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100516. Date of Electronic Publication: 2021 Mar 04.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

TGF-β-induced cell motility requires downregulation of ARHGAPs to sustain Rac1 activity.

  • Authors : Motizuki M; Department of Biochemistry, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.; Koinuma D

Subjects: Cell Movement* ; Epithelial-Mesenchymal Transition*; GTPase-Activating Proteins/GTPase-Activating Proteins/GTPase-Activating Proteins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100545. Date of Electronic Publication: 2021 Mar 17.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation.

  • Authors : Arya RK; Department of Nutrition and Food Science, University of Maryland, College Park, Maryland, USA.; Goswami R

Subjects: Giant Cells/Giant Cells/Giant Cells/*metabolism ; Giant Cells, Foreign-Body/Giant Cells, Foreign-Body/Giant Cells, Foreign-Body/*metabolism ; Macrophages/Macrophages/Macrophages/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100129. Date of Electronic Publication: 2020 Dec 04.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Evaluation of active Rac1 levels in cancer cells: A case of misleading conclusions from immunofluorescence analysis.

  • Authors : Baker MJ; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: .; Cooke M

Subjects: Cell Membrane/Cell Membrane/Cell Membrane/*metabolism ; Guanosine Triphosphate/Guanosine Triphosphate/Guanosine Triphosphate/*metabolism ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Oct 02; Vol. 295 (40), pp. 13698-13710. Date of Electronic Publication: 2020 Aug 14.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1

  • Authors : Mund JA; Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana.

Subjects: Gene Knockdown Techniques* ; Neoplasms, Second Primary*/Neoplasms, Second Primary*/Neoplasms, Second Primary*/enzymology ; Neoplasms, Second Primary*/Neoplasms, Second Primary*/Neoplasms, Second Primary*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Jul 17; Vol. 295 (29), pp. 9948-9958. Date of Electronic Publication: 2020 May 29.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42.

  • Authors : Gorisse L; Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland 20892.; Li Z

Subjects: Ubiquitination*; Arginine/Arginine/Arginine/*metabolism ; Lysine/Lysine/Lysine/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Apr 10; Vol. 295 (15), pp. 4822-4835. Date of Electronic Publication: 2020 Feb 24.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Identification of a truncated β1-chimaerin variant that inactivates nuclear Rac1.

  • Authors : Casado-Medrano V; Instituto de Biología y Genética Molecular, Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Valladolid, 47003 Valladolid, Spain.; Barrio-Real L

Subjects: Cell Nucleus/Cell Nucleus/Cell Nucleus/*metabolism ; Chimerin Proteins/Chimerin Proteins/Chimerin Proteins/*genetics ; Chimerin Proteins/Chimerin Proteins/Chimerin Proteins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Jan 31; Vol. 295 (5), pp. 1300-1314. Date of Electronic Publication: 2019 Dec 22.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks.

  • Authors : Civciristov S; Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia.; Huang C

Subjects: Analgesics, Opioid/Analgesics, Opioid/Analgesics, Opioid/*metabolism ; Receptors, Opioid, mu/Receptors, Opioid, mu/Receptors, Opioid, mu/*metabolism ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Nov 01; Vol. 294 (44), pp. 16198-16213. Date of Electronic Publication: 2019 Sep 12.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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  • 1-10 of  439 results for ""rac1 GTP-Binding Protein""