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Academic Journal

Proximity Labeling Proteomics Reveals Kv1.3 Potassium Channel Immune Interactors in Microglia.

  • Authors : Bowen CA; Center for Neurodegenerative Diseases, Emory University, Atlanta, Georgia, USA; Department of Biochemistry, Emory University, Atlanta, Georgia, USA.

Subjects: Kv1.3 Potassium Channel*/Kv1.3 Potassium Channel*/Kv1.3 Potassium Channel*/metabolism ; Microglia*/Microglia*/Microglia*/metabolism ; Proteomics*/Proteomics*/Proteomics*/methods

  • Source: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2024 Aug; Vol. 23 (8), pp. 100809. Date of Electronic Publication: 2024 Jun 25.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Proteome, Lysine Acetylome, and Succinylome Identify Posttranslational Modification of STAT1 as a Novel Drug Target in Silicosis.

  • Authors : Zhang T; State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.; Wang Y

Subjects: Silicosis*/Silicosis*/Silicosis*/metabolism ; Silicosis*/Silicosis*/Silicosis*/drug therapy ; Silicosis*/Silicosis*/Silicosis*/pathology

  • Source: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2024 Jun; Vol. 23 (6), pp. 100770. Date of Electronic Publication: 2024 Apr 17.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

African swine fever virus pB475L evades host antiviral innate immunity via targeting STAT2 to inhibit IFN-I signaling.

  • Authors : Huang Z; Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China; Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, Shaoguan University, Shaoguan, China

Subjects: African Swine Fever Virus*/African Swine Fever Virus*/African Swine Fever Virus*/immunology ; African Swine Fever Virus*/African Swine Fever Virus*/African Swine Fever Virus*/genetics ; Immunity, Innate*

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jul; Vol. 300 (7), pp. 107472. Date of Electronic Publication: 2024 Jun 13.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Inhibition of the Na + /K + -ATPase by cardiac glycosides suppresses expression of the IDO1 immune checkpoint in cancer cells by reducing STAT1 activation.

  • Authors : Shandell MA; Department of Biology, University of York, York, United Kingdom; Hull York Medical School, University of York, York, United Kingdom

Subjects: Cardiac Glycosides*/Cardiac Glycosides*/Cardiac Glycosides*/pharmacology ; Indoleamine-Pyrrole 2,3,-Dioxygenase*/Indoleamine-Pyrrole 2,3,-Dioxygenase*/Indoleamine-Pyrrole 2,3,-Dioxygenase*/antagonists & inhibitors ; Indoleamine-Pyrrole 2,3,-Dioxygenase*/Indoleamine-Pyrrole 2,3,-Dioxygenase*/Indoleamine-Pyrrole 2,3,-Dioxygenase*/biosynthesis

  • Source: The Journal of biological chemistry [J Biol Chem] 2022 Mar; Vol. 298 (3), pp. 101707. Date of Electronic Publication: 2022 Feb 09.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

A family-wide assessment of latent STAT transcription factor interactions reveals divergent dimer repertoires.

  • Authors : Begitt A; School of Life Sciences, The University of Nottingham, Nottingham, UK.; Krause S

Subjects: Gene Expression Regulation* ; Trans-Activators*/Trans-Activators*/Trans-Activators*/metabolism ; STAT Transcription Factors*/STAT Transcription Factors*/STAT Transcription Factors*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2023 May; Vol. 299 (5), pp. 104703. Date of Electronic Publication: 2023 Apr 12.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling.

  • Authors : Duval R; Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.; Bui LC

Subjects: Benzene*/Benzene*/Benzene*/pharmacokinetics ; Benzene*/Benzene*/Benzene*/pharmacology ; Leukemia*/Leukemia*/Leukemia*/genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Aug 16; Vol. 294 (33), pp. 12483-12494. Date of Electronic Publication: 2019 Jun 27.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1.

  • Authors : Feng K; From the State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China and.; the University of Chinese Academy of Sciences, Beijing 101408, China.

Subjects: Antiviral Agents/Antiviral Agents/Antiviral Agents/*pharmacology ; Bunyaviridae Infections/Bunyaviridae Infections/Bunyaviridae Infections/*immunology ; Cell Nucleus/Cell Nucleus/Cell Nucleus/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Jun 14; Vol. 294 (24), pp. 9503-9517. Date of Electronic Publication: 2019 Apr 30.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.

  • Authors : Kosciuczuk EM; From the Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois 60611.; the Division of Hematology-Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.

Subjects: Signal Transduction*; Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*metabolism ; Interferon Type I/Interferon Type I/Interferon Type I/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Jan 18; Vol. 294 (3), pp. 827-837. Date of Electronic Publication: 2018 Nov 28.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Tumor STAT1 transcription factor activity enhances breast tumor growth and immune suppression mediated by myeloid-derived suppressor cells.

  • Authors : Hix LM; Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.; Karavitis J

Subjects: Immune Tolerance*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*immunology ; Carcinoma, Intraductal, Noninfiltrating/Carcinoma, Intraductal, Noninfiltrating/Carcinoma, Intraductal, Noninfiltrating/*immunology

  • Source: The Journal of biological chemistry [J Biol Chem] 2013 Apr 26; Vol. 288 (17), pp. 11676-88. Date of Electronic Publication: 2013 Mar 13.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Dual regulation of Stat1 and Stat3 by the tumor suppressor protein PML contributes to interferon α-mediated inhibition of angiogenesis.

  • Authors : Hsu KS; From the Department of Biochemistry and.; Zhao X

Subjects: Endothelium, Vascular/Endothelium, Vascular/Endothelium, Vascular/*metabolism ; Interferon-alpha/Interferon-alpha/Interferon-alpha/*metabolism ; Neovascularization, Pathologic/Neovascularization, Pathologic/Neovascularization, Pathologic/*prevention & control

  • Source: The Journal of biological chemistry [J Biol Chem] 2017 Jun 16; Vol. 292 (24), pp. 10048-10060. Date of Electronic Publication: 2017 Apr 21.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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