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The NADPH oxidase 2 subunit p47 phox binds to the WAVE regulatory complex and p22 phox in a mutually exclusive manner.

  • Authors : Kuihon SVNP; Roy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, Iowa, USA.; Sevart BJ

Subjects: NADPH Oxidase 2*/NADPH Oxidase 2*/NADPH Oxidase 2*/metabolism ; NADPH Oxidase 2*/NADPH Oxidase 2*/NADPH Oxidase 2*/genetics ; Wiskott-Aldrich Syndrome Protein Family*/Wiskott-Aldrich Syndrome Protein Family*/Wiskott-Aldrich Syndrome Protein Family*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Apr; Vol. 300 (4), pp. 107130. Date of Electronic Publication: 2024 Mar 01.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Rac-dependent feedforward autoactivation of NOX2 leads to oxidative burst.

  • Authors : Hoang HM; Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, Texas, USA.; Johnson HE

Subjects: NADPH Oxidase 2/NADPH Oxidase 2/NADPH Oxidase 2/*metabolism ; Reactive Oxygen Species/Reactive Oxygen Species/Reactive Oxygen Species/*metabolism ; Superoxides/Superoxides/Superoxides/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2021 Aug; Vol. 297 (2), pp. 100982. Date of Electronic Publication: 2021 Jul 20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation.

  • Authors : Zielonka J; From the Department of Biophysics and Free Radical Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, .; Zielonka M

Subjects: High-Throughput Screening Assays*; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Membrane Glycoproteins/Membrane Glycoproteins/Membrane Glycoproteins/*antagonists & inhibitors

  • Source: The Journal of biological chemistry [J Biol Chem] 2016 Mar 25; Vol. 291 (13), pp. 7029-44. Date of Electronic Publication: 2016 Feb 02.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Lipopolysaccharide (LPS)-mediated angiopoietin-2-dependent autocrine angiogenesis is regulated by NADPH oxidase 2 (Nox2) in human pulmonary microvascular endothelial cells.

Subjects: Angiopoietin-2/Angiopoietin-2/Angiopoietin-2/*metabolism ; Endothelial Cells/Endothelial Cells/Endothelial Cells/*drug effects ; Lipopolysaccharides/Lipopolysaccharides/Lipopolysaccharides/*pharmacology

  • Source: The Journal of biological chemistry [J Biol Chem] 2015 Feb 27; Vol. 290 (9), pp. 5449-61. Date of Electronic Publication: 2015 Jan 07.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Toll-like receptor 2 mediates peripheral nerve injury-induced NADPH oxidase 2 expression in spinal cord microglia.

  • Authors : Lim H; Department of Neuroscience and Physiology, Dental Research Institute, and Brain Korea 21, School of Dentistry, Seoul National University, Seoul 110-799, Korea; Interdisciplinary Program in Neuroscience, College of Natural Science, Seoul National University, Seoul 110-799, Korea.

Subjects: Gene Expression Regulation, Enzymologic*; Microglia/Microglia/Microglia/*metabolism ; Peripheral Nerve Injuries/Peripheral Nerve Injuries/Peripheral Nerve Injuries/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2013 Mar 15; Vol. 288 (11), pp. 7572-7579. Date of Electronic Publication: 2013 Feb 05.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex.

  • Authors : Ma C; Division of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA. ; Wang N

Subjects: Antigens, CD/Antigens, CD/Antigens, CD/*physiology ; Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*genetics ; Class III Phosphatidylinositol 3-Kinases/Class III Phosphatidylinositol 3-Kinases/Class III Phosphatidylinositol 3-Kinases/*genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2012 May 25; Vol. 287 (22), pp. 18359-65. Date of Electronic Publication: 2012 Apr 09.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Reactive oxygen species generated by NADPH oxidase 2 and 4 are required for chondrogenic differentiation.

  • Authors : Kim KS; Laboratory of Cellular and Molecular Biochemistry, School of Life Sciences and Biotechnology, Korea University, Seoul 136-701, Korea.; Choi HW

Subjects: Cell Differentiation/Cell Differentiation/Cell Differentiation/*physiology ; Chondrocytes/Chondrocytes/Chondrocytes/*enzymology ; Chondrogenesis/Chondrogenesis/Chondrogenesis/*physiology

  • Source: The Journal of biological chemistry [J Biol Chem] 2010 Dec 17; Vol. 285 (51), pp. 40294-302. Date of Electronic Publication: 2010 Oct 15.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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The molecular basis for immune dysregulation by the hyperactivated E62K mutant of the GTPase RAC2.

  • Authors : Arrington ME; Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina, USA.; Temple B

Subjects: Mutation, Missense*; Guanosine Triphosphate/Guanosine Triphosphate/Guanosine Triphosphate/*chemistry ; rac GTP-Binding Proteins/rac GTP-Binding Proteins/rac GTP-Binding Proteins/*chemistry

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Aug 21; Vol. 295 (34), pp. 12130-12142. Date of Electronic Publication: 2020 Jul 07.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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A Proteomics-Based Assessment of Inflammation Signatures in Endotoxemia.

  • Authors : Burnap SA; King's College London British Heart Foundation Centre, School of Cardiovascular Medicine and Sciences, London, United Kingdom.; Mayr U

Subjects: Blood Proteins/Blood Proteins/Blood Proteins/*metabolism ; Endotoxemia/Endotoxemia/Endotoxemia/*metabolism ; Lipopolysaccharides/Lipopolysaccharides/Lipopolysaccharides/*pharmacology

  • Source: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2021; Vol. 20, pp. 100021. Date of Electronic Publication: 2021 Feb 24.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling.

  • Authors : Heppner DE; From the Department of Pathology and Laboratory Medicine, University of Vermont, Burlington, Vermont 05405.; Hristova M

Subjects: Signal Transduction*; ErbB Receptors/ErbB Receptors/ErbB Receptors/*metabolism ; Membrane Glycoproteins/Membrane Glycoproteins/Membrane Glycoproteins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2016 Oct 28; Vol. 291 (44), pp. 23282-23293. Date of Electronic Publication: 2016 Sep 20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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  • 1-10 of  93 results for ""NADPH Oxidase 2""