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Academic Journal

Epidermal keratinocytes regulate hyaluronan metabolism via extracellularly secreted hyaluronidase 1 and hyaluronan synthase 3.

  • Authors : Abe M; Department of Cosmetic Health Science, Gifu Pharmaceutical University, Gifu, Japan.; Masuda M

Subjects: Hyaluronoglucosaminidase*/Hyaluronoglucosaminidase*/Hyaluronoglucosaminidase*/metabolism ; Hyaluronoglucosaminidase*/Hyaluronoglucosaminidase*/Hyaluronoglucosaminidase*/genetics ; Hyaluronan Synthases*/Hyaluronan Synthases*/Hyaluronan Synthases*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jul; Vol. 300 (7), pp. 107449. Date of Electronic Publication: 2024 Jun 04.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3.

  • Authors : Bart G; From the Institute of Biomedicine/Anatomy, University of Eastern Finland, FI-70211 Kuopio, Finland.; Vico NO

Subjects: Fluorescence Resonance Energy Transfer* ; Protein Multimerization*; Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*chemistry

  • Source: The Journal of biological chemistry [J Biol Chem] 2015 May 01; Vol. 290 (18), pp. 11479-90. Date of Electronic Publication: 2015 Mar 20.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-κB and expression of the long-noncoding RNA HAS2-AS1.

  • Authors : Caon I; Department of Medicine and Surgery, University of Insubria via J. H. Dunant 5, 21100 Varese, Italy.; Bartolini B

Subjects: Gene Expression Regulation*/Gene Expression Regulation*/Gene Expression Regulation*/drug effects; Cell Nucleus/Cell Nucleus/Cell Nucleus/*metabolism ; Hyaluronan Synthases/Hyaluronan Synthases/Hyaluronan Synthases/*genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Mar 13; Vol. 295 (11), pp. 3485-3496. Date of Electronic Publication: 2020 Jan 13.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

HYBID (alias KIAA1199/CEMIP) and hyaluronan synthase coordinately regulate hyaluronan metabolism in histamine-stimulated skin fibroblasts.

  • Authors : Yoshida H; Department of Biological Science Research, Kao Corporation, Odawara-shi, Kanagawa, 250-0002 Japan. Electronic address: .; Aoki M

Subjects: Fibroblasts/Fibroblasts/Fibroblasts/*metabolism ; Histamine/Histamine/Histamine/*pharmacology ; Hyaluronan Synthases/Hyaluronan Synthases/Hyaluronan Synthases/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2020 Feb 21; Vol. 295 (8), pp. 2483-2494. Date of Electronic Publication: 2020 Jan 16.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Hyaluronan synthase 2 (HAS2) overexpression diminishes the procatabolic activity of chondrocytes by a mechanism independent of extracellular hyaluronan.

  • Authors : Ishizuka S; Department of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834.; Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

Subjects: Chondrocytes/Chondrocytes/Chondrocytes/*metabolism ; Hyaluronan Synthases/Hyaluronan Synthases/Hyaluronan Synthases/*metabolism ; Hyaluronic Acid/Hyaluronic Acid/Hyaluronic Acid/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Sep 13; Vol. 294 (37), pp. 13562-13579. Date of Electronic Publication: 2019 Jul 03.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Low dose ultraviolet B irradiation increases hyaluronan synthesis in epidermal keratinocytes via sequential induction of hyaluronan synthases Has1-3 mediated by p38 and Ca2+/calmodulin-dependent protein kinase II (CaMKII) signaling.

  • Authors : Rauhala L; School of Medicine, Institute of Biomedicine/Anatomy, University of Eastern Finland, Kuopio Campus, Yliopistonranta 1 E, P.O. Box 1627, 70211 Kuopio, Finland. ; Hämäläinen L

Subjects: Ultraviolet Rays*; Calcium-Calmodulin-Dependent Protein Kinase Type 2/Calcium-Calmodulin-Dependent Protein Kinase Type 2/Calcium-Calmodulin-Dependent Protein Kinase Type 2/*metabolism ; Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*biosynthesis

  • Source: The Journal of biological chemistry [J Biol Chem] 2013 Jun 21; Vol. 288 (25), pp. 17999-8012. Date of Electronic Publication: 2013 May 03.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Hyaluronan synthases: a decade-plus of novel glycosyltransferases.

  • Authors : Weigel PH; Department of Biochemistry and Molecular Biology and the Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA. ; DeAngelis PL

Subjects: Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*classification ; Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*genetics ; Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2007 Dec 21; Vol. 282 (51), pp. 36777-81. Date of Electronic Publication: 2007 Nov 01.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Heregulin-mediated ErbB2-ERK signaling activates hyaluronan synthases leading to CD44-dependent ovarian tumor cell growth and migration.

  • Authors : Bourguignon LY; Department of Medicine, University of California at San Francisco, USA. ; Gilad E

Subjects: Cell Movement*/Cell Movement*/Cell Movement*/drug effects ; MAP Kinase Signaling System*/MAP Kinase Signaling System*/MAP Kinase Signaling System*/drug effects ; cdc42 GTP-Binding Protein*/cdc42 GTP-Binding Protein*/cdc42 GTP-Binding Protein*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2007 Jul 06; Vol. 282 (27), pp. 19426-41. Date of Electronic Publication: 2007 May 10.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Hyaluronan biosynthesis by class I streptococcal hyaluronan synthases occurs at the reducing end.

  • Authors : Tlapak-Simmons VL; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.; Baron CA

Subjects: Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*chemistry ; Hyaluronic Acid/Hyaluronic Acid/Hyaluronic Acid/*biosynthesis ; Streptococcus/Streptococcus/Streptococcus/*enzymology

  • Source: The Journal of biological chemistry [J Biol Chem] 2005 Apr 01; Vol. 280 (13), pp. 13012-8. Date of Electronic Publication: 2005 Jan 24.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation.

  • Authors : Itano N; Institute for Molecular Science of Medicine, Aichi Medical University, Nagakute, Aichi 480-1195, Japan. ; Sawai T

Subjects: Gene Expression Regulation, Neoplastic*; Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/*metabolism ; Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2004 Apr 30; Vol. 279 (18), pp. 18679-87. Date of Electronic Publication: 2004 Jan 14.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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  • 1-10 of  117 results for ""Hyaluronan Synthases""