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Academic Journal

Focal-adhesion kinase regulates the sialylation of N-glycans via the PI4KIIα-PI4P pathway.

  • Authors : Sun Y; Division of Regulatory Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi, Japan.; Isaji T

Subjects: Focal Adhesion Kinase 1*/Focal Adhesion Kinase 1*/Focal Adhesion Kinase 1*/metabolism ; Polysaccharides*/Polysaccharides*/Polysaccharides*/metabolism ; Signal Transduction*

  • Source: The Journal of biological chemistry [J Biol Chem] 2023 Aug; Vol. 299 (8), pp. 105051. Date of Electronic Publication: 2023 Jul 13.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion.

  • Authors : Chatterjee T; The Brown Foundation Institute of Molecular Medicine and Center for Translational Cancer Research, University of Texas Health Science Center at Houston, Houston, Texas, USA.; Zhang S

Subjects: Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*genetics ; Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*genetics ; Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/*genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100261. Date of Electronic Publication: 2021 Jan 08.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Syndecan-2 cytoplasmic domain up-regulates matrix metalloproteinase-7 expression via the protein kinase Cγ-mediated FAK/ERK signaling pathway in colon cancer.

  • Authors : Jang B; From the Department of Life Sciences, Research Center for Cellular Homeostasis, Ewha Womans University, Seoul 03760 and.; Jung H

Subjects: MAP Kinase Signaling System*/MAP Kinase Signaling System*/MAP Kinase Signaling System*/drug effects ; Protein Processing, Post-Translational*/Protein Processing, Post-Translational*/Protein Processing, Post-Translational*/drug effects; Carcinoma/Carcinoma/Carcinoma/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2017 Sep 29; Vol. 292 (39), pp. 16321-16332. Date of Electronic Publication: 2017 Aug 16.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.

  • Authors : Alekhina O; From the Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.; Marchese A

Subjects: Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; Chemotaxis/Chemotaxis/Chemotaxis/*physiology ; Endosomal Sorting Complexes Required for Transport/Endosomal Sorting Complexes Required for Transport/Endosomal Sorting Complexes Required for Transport/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2016 Dec 09; Vol. 291 (50), pp. 26083-26097. Date of Electronic Publication: 2016 Oct 27.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

The Interaction between Cancer Stem Cell Marker CD133 and Src Protein Promotes Focal Adhesion Kinase (FAK) Phosphorylation and Cell Migration.

  • Authors : Liu C; From the Key Laboratory of Glycoconjugates Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, Shanghai Medical College of Fudan University, Shanghai 200032, China and.; Li Y

Subjects: Cell Movement*; AC133 Antigen/AC133 Antigen/AC133 Antigen/*metabolism ; Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2016 Jul 22; Vol. 291 (30), pp. 15540-50. Date of Electronic Publication: 2016 May 24.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Protein Kinase C Phosphorylation of a γ-Protocadherin C-terminal Lipid Binding Domain Regulates Focal Adhesion Kinase Inhibition and Dendrite Arborization.

  • Authors : Keeler AB; Department of Biology, The University of Iowa, Iowa City, Iowa 52242; Neuroscience Graduate Program, The University of Iowa, Iowa City, Iowa 52242.

Subjects: Cadherins/Cadherins/Cadherins/*metabolism ; Cerebral Cortex/Cerebral Cortex/Cerebral Cortex/*metabolism ; Dendrites/Dendrites/Dendrites/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2015 Aug 21; Vol. 290 (34), pp. 20674-20686. Date of Electronic Publication: 2015 Jul 02.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Mitsugumin 53 (MG53) ligase ubiquitinates focal adhesion kinase during skeletal myogenesis.

  • Authors : Nguyen N; From the Division of Life Sciences, Korea University, Seoul 136-701, Korea.; Yi JS

Subjects: Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*metabolism ; Muscle Development/Muscle Development/Muscle Development/*physiology

  • Source: The Journal of biological chemistry [J Biol Chem] 2014 Feb 07; Vol. 289 (6), pp. 3209-16. Date of Electronic Publication: 2013 Dec 16.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Focal adhesion kinase-dependent activation of the early endocytic protein Rab5 is associated with cell migration.

  • Authors : Arriagada C; Institute for Research in Dental Sciences, Faculty of Dentistry, Universidad de Chile, Santiago 8380000, Chile.; Silva P

Subjects: Cell Movement*; Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*metabolism ; rab5 GTP-Binding Proteins/rab5 GTP-Binding Proteins/rab5 GTP-Binding Proteins/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2019 Aug 23; Vol. 294 (34), pp. 12836-12845. Date of Electronic Publication: 2019 Jul 10.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

LKB1 represses focal adhesion kinase (FAK) signaling via a FAK-LKB1 complex to regulate FAK site maturation and directional persistence.

  • Authors : Kline ER; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.; Shupe J

Subjects: Cell Movement* ; Signal Transduction*; Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2013 Jun 14; Vol. 288 (24), pp. 17663-74. Date of Electronic Publication: 2013 May 01.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity.

  • Authors : Fan H; Division of Molecular Medicine and Genetics, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.; Guan JL

Subjects: Signal Transduction*; Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*metabolism ; Focal Adhesion Kinase 2/Focal Adhesion Kinase 2/Focal Adhesion Kinase 2/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2011 May 27; Vol. 286 (21), pp. 18573-82. Date of Electronic Publication: 2011 Apr 06.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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