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Publisher : elsevier inc. on behalf of american society for biochemistry and molecular biology
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Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design.

  • Authors : Jia Z; Institute for Biological Sciences, National Research Council of Canada, Ottawa.; Hasnain S

Subjects: Protein Folding* ; Protein Structure, Secondary*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemistry

  • Source: The Journal of biological chemistry [J Biol Chem] 1995 Mar 10; Vol. 270 (10), pp. 5527-33.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Inhibition of apoptosis by Z-VAD-fmk in SMN-depleted S2 cells.

  • Authors : Ilangovan R; Department of Medicine and Program in Neuroscience, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.; Marshall WL

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Apoptosis/Apoptosis/Apoptosis/*physiology

  • Source: The Journal of biological chemistry [J Biol Chem] 2003 Aug 15; Vol. 278 (33), pp. 30993-9. Date of Electronic Publication: 2003 Jun 03.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Evidence that inhibition of cathepsin-B contributes to the neuroprotective properties of caspase inhibitor Tyr-Val-Ala-Asp-chloromethyl ketone.

  • Authors : Gray J; Neuroscience Research, GlaxoSmithKline, Third Avenue, Harlow CM19 5AW, United Kingdom.; Haran MM

Subjects: Caspase Inhibitors* ; Neuroprotective Agents*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology

  • Source: The Journal of biological chemistry [J Biol Chem] 2001 Aug 31; Vol. 276 (35), pp. 32750-5. Date of Electronic Publication: 2001 Jun 26.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Distinct pathways for stimulation of cytochrome c release by etoposide.

  • Authors : Robertson JD; Division of Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77 Stockholm, Sweden. ; Gogvadze V

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/*pharmacology ; Cytochrome c Group/Cytochrome c Group/Cytochrome c Group/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2000 Oct 20; Vol. 275 (42), pp. 32438-43.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression.

  • Authors : Lüschen S; Institut für Immunologie, Christian-Albrechts-Universität Kiel, Brunswiker Str. 4, 24105 Kiel, Germany.; Ussat S

Subjects: Adaptor Proteins, Signal Transducing*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Carrier Proteins/Carrier Proteins/Carrier Proteins/*physiology

  • Source: The Journal of biological chemistry [J Biol Chem] 2000 Aug 11; Vol. 275 (32), pp. 24670-8.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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The interaction of trifluoroacetyl peptide chloromethyl ketones with porcine pancreatic elastase. Direct evidence for nonproductive enzyme.inhibitor complexes.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Pancreatic Elastase/Pancreatic Elastase/Pancreatic Elastase/*antagonists & inhibitors; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/chemical synthesis

  • Source: The Journal of biological chemistry [J Biol Chem] 1979 Jun 25; Vol. 254 (12), pp. 5208-18.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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A potent peptide affinity reagent for the opiate receptor.

Subjects: Affinity Labels*; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Brain/Brain/Brain/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 1981 Feb 25; Vol. 256 (4), pp. 1529-32.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Incorporation of an active site inhibitor in factor VIIa alters the affinity for tissue factor.

  • Authors : Sorensen BB; Vessel Wall Biology, Health Care Discovery, Novo Nordisk A/S, Niels Steensens Vej 1, DK-2820 Gentofte, Denmark. ; Persson E

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Factor VIIa/Factor VIIa/Factor VIIa/*metabolism ; Thromboplastin/Thromboplastin/Thromboplastin/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 1997 May 02; Vol. 272 (18), pp. 11863-8.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Effect of tethered peptidylchloromethylketone inhibitors on thermal stability and domain interactions of urokinase and other serine proteases.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*antagonists & inhibitors ; Serine Endopeptidases/Serine Endopeptidases/Serine Endopeptidases/*metabolism ; Urokinase-Type Plasminogen Activator/Urokinase-Type Plasminogen Activator/Urokinase-Type Plasminogen Activator/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 1993 Aug 15; Vol. 268 (23), pp. 17211-8.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Active-site-selective labeling of blood coagulation proteinases with fluorescence probes by the use of thioester peptide chloromethyl ketones. II. Properties of thrombin derivatives as reporters of prothrombin fragment 2 binding and specificity of the labeling approach for other proteinases.

  • Authors : Bock PE; American Red Cross Blood Services, Southeastern Michigan Region Research Laboratory, Detroit 48232.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*metabolism ; Blood Coagulation Factors/Blood Coagulation Factors/Blood Coagulation Factors/*metabolism ; Enzyme Precursors/Enzyme Precursors/Enzyme Precursors/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 1992 Jul 25; Vol. 267 (21), pp. 14974-81.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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  • 1-10 of  158 results for ""Amino Acid Chloromethyl Ketones""