Search Results

Targeting furin, a cellular proprotein convertase, for COVID-19 prevention and therapeutics.

• Authors : Jiang, Xia^1,2,3 (AUTHOR); Li, Dabing^1,4 (AUTHOR); Maghsoudloo, Mazaher¹ (AUTHOR)

Subjects: *PROPROTEIN convertases; *COVID-19; *VIRUS diseases

• Source: Drug Discovery Today. Jul2024, Vol. 29 Issue 7, pN.PAG-N.PAG. 1p.

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Nutritional and Lipid Modulation of PCSK9: Effects on Cardiometabolic Risk Factors.

• Authors : Krysa, Jacqueline A.; Teik Chye Ooi; Proctor, Spencer D.

Subjects: PROPROTEIN convertases; LOW density lipoproteins; BLOOD lipids

• Source: Journal of Nutrition. Apr2017, Vol. 147 Issue 4, p473-481. 9p.

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No effect of PCSK9 inhibitors on D-dimer and fibrinogen levels in patients with familial hypercholesterolemia.

• Authors : Schol-Gelok, Suzanne^1,2; Galema-Boers, J. (Annette) M.H.²; van Gelder, Teun^1,2

Subjects: *PROPROTEIN convertases; *ENZYME inhibitors; *FIBRINOGEN

• Source: Biomedicine & Pharmacotherapy. Dec2018, Vol. 108, p1412-1414. 3p.

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Serum PCSK9 levels predict the occurrence of acute coronary syndromes in patients with severe carotid artery stenosis.

• Authors : Liberale, Luca^1,2 ; Carbone, Federico¹; Bertolotto, Maria¹

Subjects: *ACUTE coronary syndrome; *PROPROTEIN convertases; *SUBTILISINS

• Source: International Journal of Cardiology. Jul2018, Vol. 263, p138-141. 4p.

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Whole-gene Duplication of PCSK9 as a Novel Genetic Mechanism for Familial Hypercholesterolemia.

• Authors : Iacocca, Michael A.¹; Wang, Jian¹; Lagace, Thomas²

Subjects: *HYPERCHOLESTEREMIA; *PROPROTEIN convertases; *LOW density lipoproteins

• Source: Atherosclerosis (Supplements). Jun2018, Vol. 32, p9-10. 2p.

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PCSK9 as a Positive Modulator of Platelet Activation.

• Authors : Camera, Marina ; Rossetti, Laura; Barbieri, Silvia S.

Subjects: *SUBTILISINS; *PROPROTEIN convertases; *BLOOD platelet activation

• Source: Journal of the American College of Cardiology (JACC). Feb2018, Vol. 71 Issue 8, p952-954. 3p.

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Semysinthetic biflavonoid Morelloflavone-7,4′,7″,3‴,4‴-penta-O-butanoyl is a more potent inhibitor of Proprotein Convertases Subtilisin/Kexin PC1/3 than Kex2 and Furin.

• Authors : de Souza, Aline Aparecida¹ (AUTHOR); de Andrade, Débora Martins¹ (AUTHOR); Siqueira, Fábio da Silva¹ (AUTHOR)

Subjects: *PROPROTEIN convertases; *SUBTILISINS; *PROTEIN-ligand interactionsAMAZON River Region

• Source: BBA - General Subjects. Dec2021, Vol. 1865 Issue 12, pN.PAG-N.PAG. 1p.

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A novel antibody against the furin cleavage site of SARS-CoV-2 spike protein: Effects on proteolytic cleavage and ACE2 binding.

• Authors : Spelios, Michael G.¹ (AUTHOR); Capanelli, Jeanne M.¹ (AUTHOR); Li, Adam W.¹ (AUTHOR)

Subjects: *PROPROTEIN convertases; *CELL receptors; *ANGIOTENSIN converting enzyme

• Source: Immunology Letters. Feb2022, Vol. 242, p1-7. 7p.

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Characterization of endoproteolytic processing of dynorphins by proprotein convertases using mouse spinal cord S9 fractions and mass spectrometry.

• Authors : Orduna, Alberto Ruiz; Beaudry, Francis

• Source: Neuropeptides; Jun2016, Vol. 57, p85-94, 10p

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Exploration of PCSK9 as a Cardiovascular Risk Factor: Is There a Link to the Platelet?

• Authors : Gurbel, Paul A.¹ ; Navarese, Eliano P.¹; Tantry, Udaya S.¹

Subjects: *PROPROTEIN convertases; *CARDIOVASCULAR diseases risk factors; *LOW density lipoproteins

• Source: Journal of the American College of Cardiology (JACC). Sep2017, Vol. 70 Issue 12, p1463-1466. 4p.

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