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Phosphorothioate oligonucleotides separation in ion-pairing reversed-phase liquid chromatography: effect of temperature.

• Authors : Kadlecová, Zuzana¹ (AUTHOR); Kalíková, Květa¹ (AUTHOR) ; Tesařová, Eva¹ (AUTHOR)

• Source: Journal of Chromatography A. Oct2022, Vol. 1681, pN.PAG-N.PAG. 1p.

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Ion-pair reversed-phase and hydrophilic interaction chromatography methods for analysis of phosphorothioate oligonucleotides.

• Authors : Gilar, Martin¹ (AUTHOR) ; Koshel, Brooke M.¹ (AUTHOR); Birdsall, Robert E.¹ (AUTHOR)

Subjects: *OLIGONUCLEOTIDES; *ION pairs; *HYDROPHILIC interaction liquid chromatography

• Source: Journal of Chromatography A. Dec2023, Vol. 1712, pN.PAG-N.PAG. 1p.

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Phosphorothioate oligonucleotides separation in ion-pairing reversed-phase liquid chromatography: Effect of ion-pairing system.

• Authors : Kadlecová, Zuzana¹ (AUTHOR); Kalíková, Květa¹ (AUTHOR) ; Tesařová, Eva¹ (AUTHOR)

Subjects: *OLIGONUCLEOTIDES; *LIQUID chromatography; *ION pairs

• Source: Journal of Chromatography A. Aug2022, Vol. 1676, pN.PAG-N.PAG. 1p.

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A robust method using reducing inorganic salts for preventing the desulfurization of phosphorothioate oligonucleotides during the cleavage and deprotection step.

• Authors : Habuchi, Takaki¹ (AUTHOR) ; Terao, Yuri¹ (AUTHOR); Utsugi, Masayuki¹ (AUTHOR)

Subjects: *DESULFURIZATION; *SALTS; *OLIGONUCLEOTIDES

• Source: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Dec2023, Vol. 133, pN.PAG-N.PAG. 1p.

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Improvement of chemo- and stereoselectivity for phosphorothioate oligonucleotides in capillary electrophoresis by addition of cyclodextrins.

• Authors : Ghassemi K, Maryam¹ (AUTHOR) ; Demelenne, Alice¹ (AUTHOR); Crommen, Jacques¹ (AUTHOR)

Subjects: *CAPILLARY electrophoresis; *OLIGONUCLEOTIDES; *CYCLODEXTRINS

• Source: Journal of Chromatography A. Aug2022, Vol. 1676, pN.PAG-N.PAG. 1p.

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A two-step sulfurization for efficient solution-phase synthesis of phosphorothioate oligonucleotides

• Authors : Ghisaidoobe, Amar B.T.¹; de Koning, Martijn C.¹; Duynstee, Howard I.²

Subjects: *SOLUTION (Chemistry); *OLIGONUCLEOTIDES; *CHROMATOGRAPHIC analysis

• Source: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. May2008, Vol. 49 Issue 19, p3129-3132. 4p.

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The role of the Hint1 protein in the metabolism of phosphorothioate oligonucleotides drugs and prodrugs, and the release of H2S under cellular conditions.

• Authors : Krakowiak, Agnieszka¹ (AUTHOR) ; Piotrzkowska, Danuta¹ (AUTHOR); Kocoń-Rębowska, Beata¹ (AUTHOR)

Subjects: *PROTEIN metabolism; *OLIGONUCLEOTIDES; *HELA cells

• Source: Biochemical Pharmacology. May2019, Vol. 163, p250-259. 10p.

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Evaluation of size-exclusion chromatography for the analysis of phosphorothioate oligonucleotides.

• Authors : Shimoyama, Atsuko^1,2; Fujisaka, Aki^2,3; Obika, Satoshi²

Subjects: *GEL permeation chromatography; *THIOPHOSPHATES; *OLIGONUCLEOTIDE analysis

• Source: Journal of Pharmaceutical & Biomedical Analysis. Mar2017, Vol. 136, p55-65. 11p.

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Characterization of high molecular weight impurities in synthetic phosphorothioate oligonucleotides

• Authors : Kurata, Christine¹; Bradley, Kym¹; Gaus, Hans¹

Subjects: *OLIGONUCLEOTIDES; *LIQUID chromatography; *MOLECULAR weights

• Source: Bioorganic & Medicinal Chemistry Letters. Feb2006, Vol. 16 Issue 3, p607-614. 8p.

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Evaluation of hydrophilic interaction liquid chromatography, capillary zone electrophoresis and drift tube ion-mobility quadrupole time of flight mass spectrometry for the characterization of phosphodiester and phosphorothioate oligonucleotides.

• Authors : Demelenne, Alice¹ (AUTHOR); Gou, Marie-Jia¹ (AUTHOR); Nys, Gwenaël¹ (AUTHOR)

Subjects: *TIME-of-flight mass spectrometry; *HYDROPHILIC interaction liquid chromatography; *CAPILLARY electrophoresis

• Source: Journal of Chromatography A. Mar2020, Vol. 1614, pN.PAG-N.PAG. 1p.

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