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Monoclonal antibodies and aptamers: The future therapeutics for Alzheimer's disease.

• Authors : Barrera-Ocampo, Alvaro

Subjects: ALZHEIMER'S disease; MONOCLONAL antibodies; APTAMERS

• Source: Acta Pharmaceutica Sinica B; Jul2024, Vol. 14 Issue 7, p2795-2814, 20p

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1003P A first-in-human (FIH) phase I study of IPH5301, an anti-CD73 monoclonal antibody (mAb), in patients with advanced solid tumors (AST) (CHANCES, NCT05143970).

• Authors : Beaufils, M.¹ (AUTHOR); Mailliez, A.² (AUTHOR); Sfumato, P.³ (AUTHOR)

Subjects: *MONOCLONAL antibodies; *TUMORS

• Source: Annals of Oncology. 2024 Supplement 2, Vol. 35, pS682-S683. 2p.

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A Thermodynamic Approach to Characterizing Monoclonal Antibody Stability in a Subcutaneous Environment.

• Authors : Higdon, Julia R.¹ (AUTHOR); Kang, Jonghoon¹ (AUTHOR)

Subjects: *MONOCLONAL antibodies; *PROTEIN folding; *PROTEIN stability

• Source: Journal of Pharmaceutical Sciences. Aug2024, Vol. 113 Issue 8, p2656-2657. 2p.

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Monoclonal antibodies lock down SARS-CoV-2 spike.

• Authors : Huang, Hsiang-Chi^1,2,3 (AUTHOR); Angeletti, Davide^1,4 (AUTHOR)

Subjects: *MONOCLONAL antibodies; *SARS-CoV-2; *SARS-CoV-2 Omicron variant

• Source: Trends in Immunology. Nov2023, Vol. 44 Issue 11, p874-876. 3p.

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329P Nadunolimab, a first-in-class monoclonal antibody against IL1RAP, in advanced pancreatic cancer.

• Authors : Van Cutsem, E.¹ (AUTHOR); Ochsenreither, S.² (AUTHOR); Collignon, J.J.³ (AUTHOR)

Subjects: *PANCREATIC cancer; *MONOCLONAL antibodies

• Source: Annals of Oncology. 2024 Supplement 1, Vol. 35, pS138-S139. 2p.

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Is a therapeutic dengue monoclonal antibody on the way?

• Authors : Ooi, Eng Eong^1,2,3,4 (AUTHOR) ; Chan, Yvonne FZ⁵ (AUTHOR)

Subjects: *DENGUE; *MONOCLONAL antibodies

• Source: Lancet Infectious Diseases. Jun2024, Vol. 24 Issue 6, p567-568. 2p.

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Recombinant snake antivenoms get closer to the clinic.

• Authors : Laustsen, Andreas H.¹ (AUTHOR)

Subjects: *ANTIVENINS; *MONOCLONAL antibodies; *SNAKEBITES

• Source: Trends in Immunology. Apr2024, Vol. 45 Issue 4, p225-227. 3p.

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Quality Control of Personalized Drug Products – Identity and Quantity of Monoclonal Antibodies as Active Pharmaceutical Ingredient.

• Authors : Reinders, Lars M.H.^1,2,3 (AUTHOR); Klassen, Martin D.¹ (AUTHOR); Jaeger, Martin² (AUTHOR)

Subjects: *QUALITY control; *MONOCLONAL antibodies; *BEVACIZUMAB

• Source: Journal of Pharmaceutical Sciences. Aug2023, Vol. 112 Issue 8, p2142-2145. 4p.

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The effect of PCSK9 monoclonal antibodies on circulating endothelial progenitor cells in patients with cardiovascular disease.

• Authors : Gurevitz, C.¹ (AUTHOR); Ben Zadok, O. Itzhaki¹ (AUTHOR); Leshem-Lev, D.¹ (AUTHOR)

Subjects: *PROGENITOR cells; *MONOCLONAL antibodies; *ENDOTHELIAL cells

• Source: Atherosclerosis (00219150). 2023 Supplement 1, Vol. 379, pS144-S145. 2p.

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Engineering therapeutic monoclonal antibodies.

• Authors : Stone, Cosby A.; Spiller, Benjamin W.; Smith, Scott A.

• Source: Journal of Allergy & Clinical Immunology; Mar2024, Vol. 153 Issue 3, p539-548, 10p

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