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Academic Journal

Human organic anion transporting polypeptide 1B3 (OATP1B3) is more heavily N-glycosylated than OATP1B1 in extracellular loops 2 and 5.

  • Authors : Liang T; College of Pharmaceutical Sciences, Soochow University, 199 Renai Road, Suzhou Industrial Park, Suzhou, Jiangsu 215123, China.; Liu H

Subjects: Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/metabolism ; Solute Carrier Organic Anion Transporter Family Member 1B3*/Solute Carrier Organic Anion Transporter Family Member 1B3*/Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism ; Solute Carrier Organic Anion Transporter Family Member 1B3*/Solute Carrier Organic Anion Transporter Family Member 1B3*/Solute Carrier Organic Anion Transporter Family Member 1B3*/genetics

  • Source: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 278 (Pt 2), pp. 134748. Date of Electronic Publication: 2024 Aug 13.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Leucine heptad motifs within transmembrane domains affect function and oligomerization of human organic anion transporting polypeptide 1B1.

  • Authors : Ni C; College of Life Sciences, South China Agricultural University, Guangzhou, China.; Wang X

Subjects: Protein Multimerization*; Cell Membrane/Cell Membrane/Cell Membrane/*metabolism ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*metabolism

  • Source: Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2021 Apr 01; Vol. 1863 (4), pp. 183554. Date of Electronic Publication: 2021 Jan 08.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731713 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

6-Hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor elevated in renal failure patients.

  • Authors : Masuo Y; Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.; Fujita KI

Subjects: Hepatocytes/Hepatocytes/Hepatocytes/*drug effects ; Indoles/Indoles/Indoles/*pharmacology ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors

  • Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2020 Dec; Vol. 35 (6), pp. 555-562. Date of Electronic Publication: 2020 Sep 19.Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Increased plasma concentrations of an antidyslipidemic drug pemafibrate co-administered with rifampicin or cyclosporine A in cynomolgus monkeys genotyped for the organic anion transporting polypeptide 1B1.

  • Authors : Ogawa SI; Showa Pharmaceutical University, Machida, Tokyo, 194-8543, Japan; Tokyo New Drug Research Laboratories, Kowa Co., Ltd., Higashimurayama, Tokyo, 189-0022, Japan.

Subjects: Benzoxazoles/Benzoxazoles/Benzoxazoles/*blood ; Butyrates/Butyrates/Butyrates/*blood ; Cyclosporine/Cyclosporine/Cyclosporine/*blood

  • Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2020 Aug; Vol. 35 (4), pp. 354-360. Date of Electronic Publication: 2020 Apr 09.Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Drug interaction study of flavonoids toward OATP1B1 and their 3D structure activity relationship analysis for predicting hepatoprotective effects.

  • Authors : Fan X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Drug Metabolism, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.; Bai J

Subjects: Chemical and Drug Induced Liver Injury/Chemical and Drug Induced Liver Injury/Chemical and Drug Induced Liver Injury/*prevention & control ; Flavonoids/Flavonoids/Flavonoids/*pharmacology ; Liver/Liver/Liver/*drug effects

  • Source: Toxicology [Toxicology] 2020 May 15; Vol. 437, pp. 152445. Date of Electronic Publication: 2020 Apr 04.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Short-lasting inhibition of hepatic uptake transporter OATP1B1 by tyrosine kinase inhibitor pazopanib.

  • Authors : Taguchi T; Pharmacokinetics and Safety Department, Drug Research Center, Kaken Pharmaceutical Co., Ltd., 14, Shinomiya, Minamigawara-cho, Yamashina-ku, Kyoto, 607-8042, Japan; Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1102, Japan. Electronic address: .

Subjects: Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors ; Protein Kinase Inhibitors/Protein Kinase Inhibitors/Protein Kinase Inhibitors/*pharmacology ; Pyrimidines/Pyrimidines/Pyrimidines/*pharmacology

  • Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2019 Dec; Vol. 34 (6), pp. 372-379. Date of Electronic Publication: 2019 Aug 12.Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The intracellular NPxY motif is critical in maintaining the function and expression of human organic anion transporting polypeptide 1B1.

  • Authors : Wang X; College of Life Sciences, South China Agricultural University, Guangzhou, China.; Liang Y

Subjects: Amino Acid Motifs*; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*metabolism; Amino Acid Sequence

  • Source: Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2019 Jun 01; Vol. 1861 (6), pp. 1189-1196. Date of Electronic Publication: 2019 Apr 07.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731713 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Impact of pharmacogenetics on statin-induced myopathy in South-Indian subjects.

  • Authors : Ramakumari N; Department of Cardiology, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, India. Electronic address: .; Indumathi B

Subjects: Polymorphism, Genetic*; Atherosclerosis/Atherosclerosis/Atherosclerosis/*prevention & control ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*genetics

  • Source: Indian heart journal [Indian Heart J] 2018 Dec; Vol. 70 Suppl 3, pp. S120-S125. Date of Electronic Publication: 2018 Aug 10.Publisher: Elsevier Country of Publication: India NLM ID: 0374675 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Inhibition of Organic Anion Transporting Polypeptide 1B1 and 1B3 by Betulinic Acid: Effects of Preincubation and Albumin in the Media.

  • Authors : Oh Y; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea.; Jeong YS

Subjects: Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors ; Serum Albumin/Serum Albumin/Serum Albumin/*metabolism ; Solute Carrier Organic Anion Transporter Family Member 1B3/Solute Carrier Organic Anion Transporter Family Member 1B3/Solute Carrier Organic Anion Transporter Family Member 1B3/*antagonists & inhibitors

  • Source: Journal of pharmaceutical sciences [J Pharm Sci] 2018 Jun; Vol. 107 (6), pp. 1713-1723. Date of Electronic Publication: 2018 Feb 17.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Pretreatment With Rifampicin and Tyrosine Kinase Inhibitor Dasatinib Potentiates the Inhibitory Effects Toward OATP1B1- and OATP1B3-Mediated Transport.

  • Authors : Pahwa S; Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73117.; Alam K

Subjects: Dasatinib/Dasatinib/Dasatinib/*pharmacology ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors ; Protein Kinase Inhibitors/Protein Kinase Inhibitors/Protein Kinase Inhibitors/*pharmacology

  • Source: Journal of pharmaceutical sciences [J Pharm Sci] 2017 Aug; Vol. 106 (8), pp. 2123-2135. Date of Electronic Publication: 2017 Apr 01.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium:

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  • 1-10 of  93 results for ""Liver-Specific Organic Anion Transporter 1""