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Academic Journal

Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding.

  • Authors : Bimai O; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.; Banerjee I

Subjects: Ribonucleotide Reductases*/Ribonucleotide Reductases*/Ribonucleotide Reductases*/metabolism ; Ribonucleotide Reductases*/Ribonucleotide Reductases*/Ribonucleotide Reductases*/chemistry ; Adenosine Triphosphate*/Adenosine Triphosphate*/Adenosine Triphosphate*/metabolism

  • Source: ELife [Elife] 2024 Jul 05; Vol. 12. Date of Electronic Publication: 2024 Jul 05.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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Academic Journal

Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2.

  • Authors : Anderson JW; Department of Biochemistry, University of Colorado, Boulder, United States.; Vaisar D

Subjects: Adenosine Triphosphate*; Catalytic Domain ; Phosphorylation

  • Source: ELife [Elife] 2024 Mar 27; Vol. 12. Date of Electronic Publication: 2024 Mar 27.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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Academic Journal

Nucleotide binding is the critical regulator of ABCG2 conformational transitions.

  • Authors : Gyöngy Z; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.; Doctoral School of Molecular Cell and Immune Biology, University of Debrecen, Debrecen, Hungary.

Subjects: Adenosine Triphosphate*/Adenosine Triphosphate*/Adenosine Triphosphate*/metabolism; Protein Conformation

  • Source: ELife [Elife] 2023 Feb 10; Vol. 12. Date of Electronic Publication: 2023 Feb 10.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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Academic Journal

The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader.

  • Authors : Puri N; Department of Biophysics and Biophysical Chemistry, Johns Hopkins School of Medicine, Baltimore, United States.; Fernandez AJ

Subjects: DNA Replication*; Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*metabolism ; DNA, Bacterial/DNA, Bacterial/DNA, Bacterial/*biosynthesis

  • Source: ELife [Elife] 2021 May 26; Vol. 10. Date of Electronic Publication: 2021 May 26.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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Academic Journal

Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction.

  • Authors : Subramanian S; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, United States.

Subjects: ATPases Associated with Diverse Cellular Activities/ATPases Associated with Diverse Cellular Activities/ATPases Associated with Diverse Cellular Activities/*metabolism ; Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*metabolism ; Bacteriophage T4/Bacteriophage T4/Bacteriophage T4/*enzymology

  • Source: ELife [Elife] 2021 Apr 13; Vol. 10. Date of Electronic Publication: 2021 Apr 13.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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Academic Journal

Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.

  • Authors : Fei X; Department of Biology, Massachusetts Institute of Technology, Cambridge, United States.; Bell TA

Subjects: Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*metabolism ; Endopeptidase Clp/Endopeptidase Clp/Endopeptidase Clp/*chemistry ; Escherichia coli/Escherichia coli/Escherichia coli/*metabolism

  • Source: ELife [Elife] 2020 Feb 28; Vol. 9. Date of Electronic Publication: 2020 Feb 28.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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Academic Journal

The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1.

  • Authors : Sosnowski P; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France.

Subjects: ATPases Associated with Diverse Cellular Activities/ATPases Associated with Diverse Cellular Activities/ATPases Associated with Diverse Cellular Activities/*chemistry ; Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*chemistry ; RNA, Ribosomal/RNA, Ribosomal/RNA, Ribosomal/*chemistry

  • Source: ELife [Elife] 2018 Nov 26; Vol. 7. Date of Electronic Publication: 2018 Nov 26.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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Academic Journal

CryoEM structures of open dimers of gyrase A in complex with DNA illuminate mechanism of strand passage.

  • Authors : Soczek KM; Department of Molecular Biosciences, Northwestern University, Evanston, United States.; Grant T

Subjects: Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*chemistry ; DNA Gyrase/DNA Gyrase/DNA Gyrase/*chemistry ; DNA, Bacterial/DNA, Bacterial/DNA, Bacterial/*chemistry

  • Source: ELife [Elife] 2018 Nov 20; Vol. 7. Date of Electronic Publication: 2018 Nov 20.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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Academic Journal

Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP.

  • Authors : Li M; Molecular Physiology and Biophysics Section, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, United States.; Wang Y

Subjects: Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*metabolism ; Calcium/Calcium/Calcium/*metabolism ; Cations, Divalent/Cations, Divalent/Cations, Divalent/*metabolism

  • Source: ELife [Elife] 2019 Jun 24; Vol. 8. Date of Electronic Publication: 2019 Jun 24.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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Academic Journal

Neck linker docking is critical for Kinesin-1 force generation in cells but at a cost to motor speed and processivity.

  • Authors : Budaitis BG; Cellular and Molecular Biology Program, University of Michigan, Ann Arbor, United States.; Jariwala S

Subjects: Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*metabolism ; Kinesins/Kinesins/Kinesins/*chemistry ; Kinesins/Kinesins/Kinesins/*metabolism

  • Source: ELife [Elife] 2019 May 14; Vol. 8. Date of Electronic Publication: 2019 May 14.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic

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