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  • 1-10 of  612 results for ""Xenograft Model Antitumor Assays""
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Academic Journal

Gilteritinib reverses ABCB1-mediated multidrug resistance: Preclinical in vitro and animal investigations.

  • Authors : Zhang M; Department of Thyroid And Breast Surgery, Shenzhen Hospital of Southern Medical University, Shenzhen, Guangdong 510000, China.; She ML

Subjects: Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/drug effects ; Drug Resistance, Multiple*/Drug Resistance, Multiple*/Drug Resistance, Multiple*/drug effects ; Mice, Nude*

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Nov; Vol. 180, pp. 117603. Date of Electronic Publication: 2024 Oct 30.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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Academic Journal

Expediting the development of robust 5-FU-resistant colorectal cancer models using innovative combined in vivo and in vitro strategies.

  • Authors : Shao M; Department of Central Laboratory, The Second Affiliated Hospital, School of Medicine, The Chinese University of Hong Kong, Shenzhen & Longgang District People's Hospital of Shenzhen, Shenzhen 518172, China; Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen 518060, China.

Subjects: Fluorouracil*/Fluorouracil*/Fluorouracil*/pharmacology ; Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/drug effects ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/drug therapy

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Nov; Vol. 180, pp. 117576. Date of Electronic Publication: 2024 Oct 23.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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Academic Journal

Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer.

  • Authors : Xu C; Department of Biological Medicines & Shanghai Engineering Research Center of Immunotherapeutics, School of Pharmacy, Fudan University, Shanghai 201203, China.; Huang X

Subjects: Autophagy*/Autophagy*/Autophagy*/drug effects ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Nov; Vol. 180, pp. 117550. Date of Electronic Publication: 2024 Oct 16.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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Academic Journal

Sensitizing cholangiocarcinoma to chemotherapy by inhibition of the drug-export pump MRP3.

  • Authors : Asensio M; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain

Subjects: Cholangiocarcinoma*/Cholangiocarcinoma*/Cholangiocarcinoma*/drug therapy ; Cholangiocarcinoma*/Cholangiocarcinoma*/Cholangiocarcinoma*/pathology ; Cholangiocarcinoma*/Cholangiocarcinoma*/Cholangiocarcinoma*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Nov; Vol. 180, pp. 117533. Date of Electronic Publication: 2024 Oct 13.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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Academic Journal

Gingerenone A induces ferroptosis in colorectal cancer via targeting suppression of SLC7A11 signaling pathway.

  • Authors : Xiao H; State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, China; Department of General Surgery, Chongqing General Hospital, Chongqing 400013, China.

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/drug effects ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/drug therapy

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Nov; Vol. 180, pp. 117529. Date of Electronic Publication: 2024 Oct 10.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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Academic Journal

Design, synthesis and biological evaluation of dual inhibitors targeting AR/AR-Vs and PARP1 in castration resistant prostate cancer therapy.

  • Authors : Zhang SH; Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430030, China.; Su Y

Subjects: Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/drug therapy ; Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/pathology ; Poly (ADP-Ribose) Polymerase-1*/Poly (ADP-Ribose) Polymerase-1*/Poly (ADP-Ribose) Polymerase-1*/antagonists & inhibitors

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Nov; Vol. 180, pp. 117485. Date of Electronic Publication: 2024 Sep 25.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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Academic Journal

New drug combination regimen based on pharmacokinetic characteristics-Erdafitinib combined with sertraline or duloxetine.

  • Authors : Zhang XD; Department of Behavioral Medicine, Wenzhou Seventh People's Hospital, Wenzhou, Zhejiang, China; Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.

Subjects: Sertraline*/Sertraline*/Sertraline*/pharmacology ; Sertraline*/Sertraline*/Sertraline*/pharmacokinetics ; Duloxetine Hydrochloride*/Duloxetine Hydrochloride*/Duloxetine Hydrochloride*/pharmacology

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Oct; Vol. 179, pp. 117414. Date of Electronic Publication: 2024 Sep 10.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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Academic Journal

Recombinant canstatin inhibits the progression of hepatocellular carcinoma by repressing the HIF-1α/VEGF signaling pathway.

  • Authors : Zhu L; Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, Jiangnan University, Wuxi 214122, China; JITRI Future Food Technol Res Inst Co Ltd, Yixing 214200, China.

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/drug therapy ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/pathology ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Oct; Vol. 179, pp. 117423. Date of Electronic Publication: 2024 Sep 10.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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Academic Journal

Shikonin, a natural naphthoquinone phytochemical, exerts anti-leukemia effects in human CBF-AML cell lines and zebrafish xenograft models.

  • Authors : Yen JH; Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien 970374, Taiwan; Institute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan.

Subjects: Zebrafish* ; Naphthoquinones*/Naphthoquinones*/Naphthoquinones*/pharmacology ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Oct; Vol. 179, pp. 117395. Date of Electronic Publication: 2024 Sep 05.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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Academic Journal

Hyaluronidase improves the efficacy of nab-paclitaxel after prolonged angiogenesis inhibition in preclinical models for esophagogastric cancer.

  • Authors : Liu D; Amsterdam UMC Location University of Amsterdam, Center for Experimental and Molecular Medicine, Laboratory of Experimental Oncology and Radiobiology, Meibergdreef 9, Amsterdam 1105 AZ, the Netherlands; Amsterdam UMC location University of Amsterdam, Department of Medical Oncology, Meibergdreef 9, Amsterdam 1105 AZ, the Netherlands

Subjects: Paclitaxel*/Paclitaxel*/Paclitaxel*/pharmacology ; Paclitaxel*/Paclitaxel*/Paclitaxel*/administration & dosage ; Paclitaxel*/Paclitaxel*/Paclitaxel*/therapeutic use

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Sep; Vol. 178, pp. 117261. Date of Electronic Publication: 2024 Aug 05.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication

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  • 1-10 of  612 results for ""Xenograft Model Antitumor Assays""