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Academic Journal

Anti-muscle atrophy effect of fermented Tenebrio molitor larvae extract by modulating the PI3K-Akt-mTOR/FoxO3α pathway in mice treated with dexamethasone.

  • Authors : Han J; Department of Food and Nutrition, Sunchon National University, Suncheon 57922, Republic of Korea.; Choi SY

Subjects: Dexamethasone*/Dexamethasone*/Dexamethasone*/pharmacology ; TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Sep; Vol. 178, pp. 117266. Date of Electronic Publication: 2024 Aug 12.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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Academic Journal

Panax notoginseng saponins dually modulates autophagy in gastric precancerous lesions complicated with myocardial ischemia-reperfusion injury model through the PI3K/AKT/mTOR pathway.

  • Authors : Wang X; Wangjing Hospital, China Academy of Chinese Medical Sciences, No. 6, Huajiadi Street, Chaoyang District, Beijing 100102, China; Tibetan Medicine Administration of Tibet Autonomous Region, Tibetan 850000, China.

Subjects: TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism ; Saponins*/Saponins*/Saponins*/pharmacology ; Saponins*/Saponins*/Saponins*/therapeutic use

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Sep; Vol. 178, pp. 117268. Date of Electronic Publication: 2024 Aug 07.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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Academic Journal

Digirseophene A promotes recovery in injured developing cerebellum via AMPK/AKT/GSK3β pathway-mediated neural stem cell proliferation.

  • Authors : Tang X; College of Pharmacy and Laboratory Medicine, Army Medical University, No. 30 Gaotanyan Centre Street, Shapingba District, Chong Qing, China.; Huang Y

Subjects: Neural Stem Cells*/Neural Stem Cells*/Neural Stem Cells*/drug effects ; Neural Stem Cells*/Neural Stem Cells*/Neural Stem Cells*/metabolism ; Glycogen Synthase Kinase 3 beta*/Glycogen Synthase Kinase 3 beta*/Glycogen Synthase Kinase 3 beta*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Aug; Vol. 177, pp. 117046. Date of Electronic Publication: 2024 Jul 08.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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Academic Journal

A novel iheyamine A derivative L42 suppresses acute myeloid leukemia via dual regulation of the PI3K/AKT/FOXO3a axis and TNF signaling pathway.

  • Authors : Dinghuan W; Department of Pediatrics, the Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550000, PR China; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, Guizhou 550014, PR China

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/pathology ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Aug; Vol. 177, pp. 117071. Date of Electronic Publication: 2024 Jul 08.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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Academic Journal

Ruthenium complex containing 1,3-thiazolidine-2-thione inhibits hepatic cancer stem cells by suppressing Akt/mTOR signalling and leading to apoptotic and autophagic cell death.

  • Authors : Neves SP; Gonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, Bahia, 40296-710, Brazil.; Bomfim LM

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Aug; Vol. 177, pp. 117059. Date of Electronic Publication: 2024 Jul 01.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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Academic Journal

Omarigliptin/rosinidin combination ameliorates cyclophosphamide-induced lung toxicity in rats: The interaction between glucagon-like peptide-1, TXNIP/NLRP3 inflammasome signaling, and PI3K/Akt/FoxO1 axis.

  • Authors : Abd Elmaaboud MA; Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.; Kabel AM

Subjects: Cyclophosphamide*/Cyclophosphamide*/Cyclophosphamide*/toxicity ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism ; Inflammasomes*/Inflammasomes*/Inflammasomes*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Aug; Vol. 177, pp. 117026. Date of Electronic Publication: 2024 Jun 26.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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Academic Journal

Rupatadine inhibits colorectal cancer cell proliferation through the PIP5K1A/Akt/CDK2 pathway.

  • Authors : Jiang L; China Pharmaceutical University, Nanjing 210000, China; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (Zhuhai Clinical Medical College of Jinan University), Zhuhai 519000, China.

Subjects: Cell Proliferation*/Cell Proliferation*/Cell Proliferation*/drug effects ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/drug therapy ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Jul; Vol. 176, pp. 116826. Date of Electronic Publication: 2024 Jun 04.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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Academic Journal

Inhibition of glycolysis and Src/Akt signaling reduces Caveolin-1-enhanced metastasis.

  • Authors : Simón L; Nutrition and Dietetic School, Universidad Finis Terrae, Santiago, Chile; Cellular Communication Laboratory, Center for Studies on Exercise, Metabolism and Cancer (CEMC), Institute of Biomedical Sciences (ICBM), Faculty of Medicine, University of Chile, Santiago, Chile

Subjects: Caveolin 1*/Caveolin 1*/Caveolin 1*/metabolism ; Glycolysis*/Glycolysis*/Glycolysis*/drug effects ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Jul; Vol. 176, pp. 116841. Date of Electronic Publication: 2024 Jun 03.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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Academic Journal

Liensinine diperchlorate and artemisitene synergistically attenuate breast cancer progression through suppressing PI3K-AKT signaling and their efficiency in breast cancer patient-derived organoids.

  • Authors : Lin X; Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, China.; Lin T

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Jul; Vol. 176, pp. 116871. Date of Electronic Publication: 2024 Jun 10.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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Academic Journal

Butyrate improves recovery from experimental necrotizing enterocolitis by metabolite hesperetin through potential inhibition the PI3K-Akt pathway.

  • Authors : Gao Y; Key Laboratory of Quality & Safety Control for Milk and Dairy Products of Ministry of Agriculture and Rural Affairs, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

Subjects: Enterocolitis, Necrotizing*/Enterocolitis, Necrotizing*/Enterocolitis, Necrotizing*/drug therapy ; Enterocolitis, Necrotizing*/Enterocolitis, Necrotizing*/Enterocolitis, Necrotizing*/metabolism ; Enterocolitis, Necrotizing*/Enterocolitis, Necrotizing*/Enterocolitis, Necrotizing*/pathology

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Jul; Vol. 176, pp. 116876. Date of Electronic Publication: 2024 Jun 07.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic

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  • 1-10 of  696 results for ""Proto-Oncogene Proteins c-akt""