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Academic Journal

The impact of ABCB1 , CYP3A4 and CYP3A5 gene polymorphisms on apixaban trough concentration and bleeding risk in patients with atrial fibrillation.

  • Authors : Skripka AI; Department of Faculty Therapy N1, 68477 I.M. Sechenov First Moscow State Medical University (Sechenov University) , Moscow, Russian Federation.; Krupenin PM

Subjects: Atrial Fibrillation*/Atrial Fibrillation*/Atrial Fibrillation*/drug therapy ; Atrial Fibrillation*/Atrial Fibrillation*/Atrial Fibrillation*/genetics ; Pyridones*/Pyridones*/Pyridones*/pharmacokinetics

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2024 Jul 01; Vol. 39 (2), pp. 89-97. Date of Electronic Publication: 2024 Jul 01 (Print Publication: 2024).Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: eCollection Cited Medium:

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Academic Journal

A review of pharmacogenetic studies in the Bangladeshi population.

  • Authors : Mostaid MS; Department of Pharmaceutical Sciences, North South University, Dhaka, Bangladesh.; Aziz MA

Subjects: Pharmacogenomic Testing* ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics; Humans

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2023 Mar 01; Vol. 38 (2), pp. 123-131. Date of Electronic Publication: 2023 Mar 01 (Print Publication: 2023).Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: eCollection Cited Medium:

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Academic Journal

Predicting drug-drug interactions by electrochemically driven cytochrome P450 3A4 reactions.

  • Authors : Shumyantseva VV; Institute of Biomedical Chemistry, Moscow, Russia.; Pirogov Russian National Research Medical University, Moscow, Russia.

Subjects: Cytochrome P-450 CYP3A*; Catalysis ; Drug Interactions

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2021 Dec 06; Vol. 37 (3), pp. 241-248. Date of Electronic Publication: 2021 Dec 06 (Print Publication: 2022).Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: eCollection Cited Medium:

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Academic Journal

Enhanced anti-cancer activity by menthol in HepG2 cells exposed to paclitaxel and vincristine: possible involvement of CYP3A4 downregulation.

  • Authors : Nagai K; Laboratory of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Osaka Ohtani University, 3-11-1 Nishikiori-kita, Tondabayashi 584-0066, Japan, Phone/Fax: +81-721-24-9148.; Fukuno S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*metabolism ; Down-Regulation/Down-Regulation/Down-Regulation/*drug effects

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2019 Mar 06; Vol. 34 (1). Date of Electronic Publication: 2019 Mar 06.Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: Electronic Cited Medium:

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Academic Journal

The ABCB1, CYP2C19, CYP3A5 and CYP4F2 genetic polymorphisms and platelet reactivity in the early phases of acute coronary syndromes.

  • Authors : Mirzaev KB; Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation, Moscow, Russian Federation.; Rytkin E

Subjects: Acute Coronary Syndrome/Acute Coronary Syndrome/Acute Coronary Syndrome/*genetics ; Cytochrome P-450 CYP2C19/Cytochrome P-450 CYP2C19/Cytochrome P-450 CYP2C19/*genetics ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*genetics

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2018 Sep 25; Vol. 33 (3), pp. 109-118.Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: Print Cited Medium: Internet

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Academic Journal

No effect of lipoic acid on catalytic activity of cytochrome P450 3A4.

  • Authors : Makhova AA; Sechenov First Moscow State Medical University, Moscow, Russian Federation.; Shikh EV

Subjects: Antioxidants/Antioxidants/Antioxidants/*chemistry ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*metabolism ; Thioctic Acid/Thioctic Acid/Thioctic Acid/*chemistry

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2020 Jul 27; Vol. 35 (3). Date of Electronic Publication: 2020 Jul 27.Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: Electronic Cited Medium:

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Academic Journal

Pharmacogenetic relevant polymorphisms of CYP2C9, CYP2C19, CYP2D6, and CYP3A5 in Bhutanese population.

  • Authors : Dorji PW; Graduate Studies, Chulabhorn International College of Medicine, Thammasat University, Thailand; Faculty of Nursing and Public Health, Khesar Gyalpo University of Medical Sciences of Bhutan, Thimphu, Bhutan.

Subjects: Pharmacogenomic Testing* ; Polymorphism, Genetic*; Cytochrome P-450 CYP2C19/Cytochrome P-450 CYP2C19/Cytochrome P-450 CYP2C19/*genetics

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2019 Dec 18; Vol. 34 (4).Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: Print Cited Medium: Internet

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Academic Journal

Binary and ternary combinations of anti-HIV protease inhibitors: effect on gene expression and functional activity of CYP3A4 and efflux transporters.

Subjects: Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*genetics ; Gene Expression/Gene Expression/Gene Expression/*drug effects ; HIV Protease Inhibitors/HIV Protease Inhibitors/HIV Protease Inhibitors/*pharmacology

  • Source: Drug metabolism and drug interactions [Drug Metabol Drug Interact] 2014; Vol. 29 (2), pp. 101-10.Publisher: De Gruyter Country of Publication: Germany NLM ID: 8904736 Publication Model: Print Cited Medium: Internet

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Academic Journal

Drug-drug interaction (DDI) assessments of ruxolitinib, a dual substrate of CYP3A4 and CYP2C9, using a verified physiologically based pharmacokinetic (PBPK) model to support regulatory submissions.

  • Authors : Umehara K; Department of PK Sciences, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.; Novartis Institutes for BioMedical Research, Basel, Switzerland.

Subjects: Models, Biological*; Cytochrome P-450 CYP2C9/Cytochrome P-450 CYP2C9/Cytochrome P-450 CYP2C9/*metabolism ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*metabolism

  • Source: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2019 May 30; Vol. 34 (2). Date of Electronic Publication: 2019 May 30.Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: Electronic Cited Medium:

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Academic Journal

Evaluation of partial area under the concentration time curve to estimate midazolam apparent oral clearance for cytochrome P450 3A phenotyping.

Subjects: Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*metabolism ; Hypnotics and Sedatives/Hypnotics and Sedatives/Hypnotics and Sedatives/*pharmacokinetics ; Midazolam/Midazolam/Midazolam/*pharmacokinetics

  • Source: Drug metabolism and drug interactions [Drug Metabol Drug Interact] 2013; Vol. 28 (4), pp. 217-23.Publisher: De Gruyter Country of Publication: Germany NLM ID: 8904736 Publication Model: Print Cited Medium: Internet

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  • 1-10 of  46 results for ""Cytochrome P-450 CYP3A""