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Academic Journal

Spatial organization of PI3K-PI(3,4,5)P 3 -AKT signaling by focal adhesions.

  • Authors : Wang J; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Subjects: Focal Adhesions*/Focal Adhesions*/Focal Adhesions*/metabolism ; Focal Adhesions*/Focal Adhesions*/Focal Adhesions*/genetics ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism

  • Source: Molecular cell [Mol Cell] 2024 Nov 21; Vol. 84 (22), pp. 4401-4418.e9. Date of Electronic Publication: 2024 Nov 01.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation.

  • Authors : Rizza S; Redox Biology, Danish Cancer Society Research Center, 2100 Copenhagen, Denmark. Electronic address: .; Di Leo L

Subjects: Focal Adhesion Kinase 1*/Focal Adhesion Kinase 1*/Focal Adhesion Kinase 1*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Alcohol Dehydrogenase*/Alcohol Dehydrogenase*/Alcohol Dehydrogenase*/metabolism

  • Source: Cell reports [Cell Rep] 2023 Jan 31; Vol. 42 (1), pp. 111997. Date of Electronic Publication: 2023 Jan 18.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited

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Academic Journal

Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2.

  • Authors : Berger BT; Structural Genomics Consortium, Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences, Max-von-Laue-Straße 9, 60438 Frankfurt am Main, Germany.

Subjects: Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*antagonists & inhibitors ; Indoles/Indoles/Indoles/*pharmacology ; Protein Kinase Inhibitors/Protein Kinase Inhibitors/Protein Kinase Inhibitors/*pharmacology

  • Source: Cell chemical biology [Cell Chem Biol] 2021 May 20; Vol. 28 (5), pp. 686-698.e7. Date of Electronic Publication: 2021 Jan 25.Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited

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Academic Journal

CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling.

  • Authors : Oguri Y; UCSF Diabetes Center, University of California, San Francisco, San Francisco, CA, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA

Subjects: Adipogenesis/Adipogenesis/Adipogenesis/*genetics ; Adipose Tissue, Beige/Adipose Tissue, Beige/Adipose Tissue, Beige/*metabolism ; Energy Metabolism/Energy Metabolism/Energy Metabolism/*genetics

  • Source: Cell [Cell] 2020 Aug 06; Vol. 182 (3), pp. 563-577.e20. Date of Electronic Publication: 2020 Jul 01.Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells.

  • Authors : Berdan CA; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, University of California, Berkeley, Berkeley, CA 94720, USA.

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*metabolism ; Sesquiterpenes/Sesquiterpenes/Sesquiterpenes/*metabolism

  • Source: Cell chemical biology [Cell Chem Biol] 2019 Jul 18; Vol. 26 (7), pp. 1027-1035.e22. Date of Electronic Publication: 2019 May 09.Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited

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Academic Journal

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition.

  • Authors : Yoon SO; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address: .; Shin S

Subjects: Drug Resistance, Neoplasm*; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*pharmacology ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*drug therapy

  • Source: Molecular cell [Mol Cell] 2017 Aug 03; Vol. 67 (3), pp. 512-527.e4. Date of Electronic Publication: 2017 Jul 27.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.

  • Authors : Hu JK; Department of Orofacial Sciences and Program in Craniofacial Biology, University of California, San Francisco, San Francisco, CA 94143, USA.; Du W

Subjects: Cell Differentiation* ; Cell Proliferation* ; Signal Transduction*

  • Source: Cell stem cell [Cell Stem Cell] 2017 Jul 06; Vol. 21 (1), pp. 91-106.e6. Date of Electronic Publication: 2017 Apr 27.Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited

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Academic Journal

FAK Forms a Complex with MEF2 to Couple Biomechanical Signaling to Transcription in Cardiomyocytes.

  • Authors : Cardoso AC; Brazilian National Laboratory for Biosciences, Center for Research in Energy and Materials, Campinas, São Paulo 13084-971, Brazil.; Pereira AHM

Subjects: Mechanotransduction, Cellular* ; Transcription, Genetic*; Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*chemistry

  • Source: Structure (London, England : 1993) [Structure] 2016 Aug 02; Vol. 24 (8), pp. 1301-1310. Date of Electronic Publication: 2016 Jul 14.Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited

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Academic Journal

Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons.

  • Authors : Meltzer S; Howard Hughes Medical Institute, Departments of Physiology, Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.; Yadav S

Subjects: Dendrites/Dendrites/Dendrites/*physiology ; Drosophila Proteins/Drosophila Proteins/Drosophila Proteins/*metabolism ; Epidermis/Epidermis/Epidermis/*physiology

  • Source: Neuron [Neuron] 2016 Feb 17; Vol. 89 (4), pp. 741-55. Date of Electronic Publication: 2016 Feb 04.Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway.

  • Authors : Wang C; Cancer Biology Laboratory, School of Life Sciences, Tsinghua University, Beijing 100084, China; The National Engineering Laboratory for Anti-Tumor Protein Therapeutics, Tsinghua University, Beijing 100084, China

Subjects: Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/Focal Adhesion Kinase 1/*metabolism ; Integrin beta1/Integrin beta1/Integrin beta1/*metabolism

  • Source: Cell reports [Cell Rep] 2020 Feb 11; Vol. 30 (6), pp. 1780-1797.e6.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium:

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  • 1-10 of  63 results for ""Focal Adhesion Kinase 1""