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Academic Journal

Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.

  • Authors : Zhou W; State Key Laboratory of Esophageal Cancer Prevention and Treatment; Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China

Subjects: Enzyme Inhibitors*/Enzyme Inhibitors*/Enzyme Inhibitors*/pharmacology ; Liver Cirrhosis*/Liver Cirrhosis*/Liver Cirrhosis*/drug therapy ; Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/antagonists & inhibitors

  • Source: Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2022 Aug 01; Vol. 100 (4), pp. 309-324. Date of Electronic Publication: 2022 May 11.Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 8606068 Publication Model: Print-Electronic

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Academic Journal

E3 ubiquitin ligase HECW1 promotes the metastasis of non-small cell lung cancer cells through mediating the ubiquitination of Smad4.

  • Authors : Lu C; Department of Thoracic Surgery, The First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Shushan District, Hefei 230022, Anhui, China.; Ning G

Subjects: Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*metabolism ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*metabolism ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*metabolism

  • Source: Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2021 Oct; Vol. 99 (5), pp. 675-681. Date of Electronic Publication: 2021 Feb 02.Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 8606068 Publication Model: Print-Electronic

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