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Academic Journal

Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer's disease brains.

  • Authors : Sharoar MG; Department of Neuroscience, University of Connecticut Health, Farmington, CT, 06032, USA.; Palko S

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology ; Lysosomes/Lysosomes/Lysosomes/*pathology ; Neurites/Neurites/Neurites/*pathology

  • Source: Molecular neurodegeneration [Mol Neurodegener] 2021 Jul 02; Vol. 16 (1), pp. 45. Date of Electronic Publication: 2021 Jul 02.Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium:

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Academic Journal

Detection of cancer cells using SapC-DOPS nanovesicles.

  • Authors : Davis HW; Division of Hematology/Oncology, Translational Medicine Laboratory, Department of Internal Medicine, University of Cincinnati College of Medicine, and Brain Tumor Center at UC Neuroscience Institute, 3512 Eden Avenue, Cincinnati, OH, 45267-0508, USA.; Hussain N

Subjects: Nanoparticles*; Neoplasms/Neoplasms/Neoplasms/*diagnosis ; Neoplasms/Neoplasms/Neoplasms/*metabolism

  • Source: Molecular cancer [Mol Cancer] 2016 May 10; Vol. 15 (1), pp. 33. Date of Electronic Publication: 2016 May 10.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium:

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Academic Journal

SapC-DOPS - a Phosphatidylserine-targeted Nanovesicle for selective Cancer therapy.

  • Authors : N'Guessan KF; Division of Hematology/Oncology, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Subjects: Nanoparticles/Nanoparticles/Nanoparticles/*chemistry ; Neoplasms/Neoplasms/Neoplasms/*therapy ; Phosphatidylserines/Phosphatidylserines/Phosphatidylserines/*metabolism

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2020 Jan 09; Vol. 18 (1), pp. 6. Date of Electronic Publication: 2020 Jan 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium:

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Academic Journal

Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology.

  • Authors : Mendsaikhan A; Molecular Neuroscience Research Center, Shiga University of Medical Science, Seta, Otsu, Otsu, 520-2192, Japan.; Tooyama I

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology ; Lysosomes/Lysosomes/Lysosomes/*metabolism

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Dec 21; Vol. 7 (1), pp. 215. Date of Electronic Publication: 2019 Dec 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium:

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Academic Journal

Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice.

  • Authors : Sun Y; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 4006, Cincinnati, OH, USA. ; Jia L

Subjects: Gene Expression Profiling*; Brain Diseases/Brain Diseases/Brain Diseases/*genetics ; CCAAT-Enhancer-Binding Protein-delta/CCAAT-Enhancer-Binding Protein-delta/CCAAT-Enhancer-Binding Protein-delta/*genetics

  • Source: BMC neuroscience [BMC Neurosci] 2008 Aug 01; Vol. 9, pp. 76. Date of Electronic Publication: 2008 Aug 01.Publisher: BioMed Central Country of Publication: England NLM ID: 100966986 Publication Model: Electronic Cited Medium:

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Academic Journal

SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas.

  • Authors : Sulaiman MK; Division of Hematology and Oncology, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA. .; Chu Z

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Intracellular Signaling Peptides and Proteins/Intracellular Signaling Peptides and Proteins/Intracellular Signaling Peptides and Proteins/*metabolism ; Mitochondria/Mitochondria/Mitochondria/*drug effects

  • Source: Molecular cancer [Mol Cancer] 2015 Apr 08; Vol. 14, pp. 78. Date of Electronic Publication: 2015 Apr 08.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium:

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Academic Journal

Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion.

  • Authors : Hu S; Stanley S Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Delorme N

Subjects: Cell Movement* ; Down-Regulation*; Prostatic Neoplasms/Prostatic Neoplasms/Prostatic Neoplasms/*metabolism

  • Source: Molecular cancer [Mol Cancer] 2010 Feb 04; Vol. 9, pp. 30. Date of Electronic Publication: 2010 Feb 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium:

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Academic Journal

Saposin C promotes survival and prevents apoptosis via PI3K/Akt-dependent pathway in prostate cancer cells.

  • Authors : Lee TJ; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, 533 Bolivar Street, CSRB 4-17, New Orleans, LA 70112, USA. ; Sartor O

Subjects: Apoptosis/Apoptosis/Apoptosis/*physiology ; Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/*metabolism ; Prostatic Neoplasms/Prostatic Neoplasms/Prostatic Neoplasms/*genetics

  • Source: Molecular cancer [Mol Cancer] 2004 Nov 17; Vol. 3, pp. 31. Date of Electronic Publication: 2004 Nov 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium:

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Academic Journal

Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver.

Subjects: FASCIOLA hepatica; CELL analysis; PROTEOMICS

  • Source: BMC Genomics; 1/11/2021, Vol. 22 Issue 1, p1-16, 16p

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Academic Journal

Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion.

Subjects: PROSTATE cancer; METASTASIS; CANCER invasiveness

  • Source: Molecular Cancer; 2010, Vol. 9, Special section p1-18, 18p, 1 Color Photograph, 5 Graphs

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  • 1-10 of  69 results for ""Saposins""