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Editorial & Opinion

Lessons from PROMINENT and prospects for pemafibrate.

  • Authors : Fruchart JC; Residual Risk Reduction Initiative (R3i) Foundation, Picassoplatz 8, Basel, 4010, Switzerland. .; Fruchart-Najib J

Subjects: Benzoxazoles*/Benzoxazoles*/Benzoxazoles*/therapeutic use ; Benzoxazoles*/Benzoxazoles*/Benzoxazoles*/adverse effects ; Butyrates*/Butyrates*/Butyrates*/therapeutic use

  • Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2024 Jul 29; Vol. 23 (1), pp. 279. Date of Electronic Publication: 2024 Jul 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium:

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Academic Journal

Exploring the biocombinatorial potential of benzoxazoles: generation of novel caboxamycin derivatives.

  • Authors : Losada AA; Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, C/Julian Claveria s/n, 33006, Oviedo, Asturias, Spain.; Méndez C

Subjects: Benzoxazoles/Benzoxazoles/Benzoxazoles/*metabolism ; Polyketide Synthases/Polyketide Synthases/Polyketide Synthases/*metabolism ; Streptomyces/Streptomyces/Streptomyces/*metabolism

  • Source: Microbial cell factories [Microb Cell Fact] 2017 May 25; Vol. 16 (1), pp. 93. Date of Electronic Publication: 2017 May 25.Publisher: BioMed Central Country of Publication: England NLM ID: 101139812 Publication Model: Electronic Cited Medium:

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Academic Journal

Effects of pemafibrate on glucose metabolism markers and liver function tests in patients with hypertriglyceridemia: a pooled analysis of six phase 2 and phase 3 randomized double-blind placebo-controlled clinical trials.

  • Authors : Yokote K; Department of Endocrinology, Hematology and Gerontology, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan. .; Department of Diabetes, Metabolism and Endocrinology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan. .

Subjects: Liver Function Tests*; Benzoxazoles/Benzoxazoles/Benzoxazoles/*therapeutic use ; Blood Glucose/Blood Glucose/Blood Glucose/*drug effects

  • Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2021 May 04; Vol. 20 (1), pp. 96. Date of Electronic Publication: 2021 May 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium:

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Academic Journal

Marked effects of novel selective peroxisome proliferator-activated receptor α modulator, pemafibrate in severe hypertriglyceridemia: preliminary report.

  • Authors : Iitake C; Iitake Clinic for Internal Medicine, 2131-1976 Migawacho, Mito City, Ibaraki, 310-0913, Japan. .; Masuda D

Subjects: Benzoxazoles/Benzoxazoles/Benzoxazoles/*therapeutic use ; Butyrates/Butyrates/Butyrates/*therapeutic use ; Hypertriglyceridemia/Hypertriglyceridemia/Hypertriglyceridemia/*drug therapy

  • Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2020 Nov 27; Vol. 19 (1), pp. 201. Date of Electronic Publication: 2020 Nov 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium:

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Academic Journal

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation.

Subjects: Benzoxazoles/Benzoxazoles/Benzoxazoles/*therapeutic use ; Butyrates/Butyrates/Butyrates/*therapeutic use ; Cardiovascular Diseases/Cardiovascular Diseases/Cardiovascular Diseases/*prevention & control

  • Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2019 Jun 04; Vol. 18 (1), pp. 71. Date of Electronic Publication: 2019 Jun 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium:

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Academic Journal

Efficacy and safety of pemafibrate administration in patients with dyslipidemia: a systematic review and meta-analysis.

  • Authors : Ida S; Department of Diabetes and Metabolism, Ise Red Cross Hospital, 1-471-2, Funae, 1-Chome, Ise-shi, Mie, 516-8512, Japan. .; Kaneko R

Subjects: Benzoxazoles/Benzoxazoles/Benzoxazoles/*therapeutic use ; Butyrates/Butyrates/Butyrates/*therapeutic use ; Dyslipidemias/Dyslipidemias/Dyslipidemias/*drug therapy

  • Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2019 Mar 21; Vol. 18 (1), pp. 38. Date of Electronic Publication: 2019 Mar 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium:

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Academic Journal

Pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor alpha modulator for management of atherogenic dyslipidaemia.

  • Authors : Fruchart JC; R3i Foundation, St. Alban-Anlage 46, Basel, Switzerland. .

Subjects: Disease Management*; Atherosclerosis/Atherosclerosis/Atherosclerosis/*drug therapy ; Benzoxazoles/Benzoxazoles/Benzoxazoles/*therapeutic use

  • Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2017 Oct 04; Vol. 16 (1), pp. 124. Date of Electronic Publication: 2017 Oct 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium:

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Academic Journal

Pemafibrate decreases triglycerides and small, dense LDL, but increases LDL-C depending on baseline triglycerides and LDL-C in type 2 diabetes patients with hypertriglyceridemia: an observational study.

  • Authors : Komiya I; Department of Internal Medicine, Okinawa Medical Hospital, 2310 Tsuhako-Nishihara, Sashiki, Nanjo, Okinawa, 9011414, Japan. .; Department of Diabetes and Endocrinology, Medical Plaza Daido Central, 123 Daido, Naha, Okinawa, 9020066, Japan. .

Subjects: Benzoxazoles/Benzoxazoles/Benzoxazoles/*administration & dosage ; Butyrates/Butyrates/Butyrates/*administration & dosage ; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*drug therapy

  • Source: Lipids in health and disease [Lipids Health Dis] 2021 Feb 20; Vol. 20 (1), pp. 17. Date of Electronic Publication: 2021 Feb 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101147696 Publication Model: Electronic Cited Medium:

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Academic Journal

Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet.

  • Authors : Yoshida M; Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.; Nakamura K

Subjects: Diet, High-Fat* ; Sodium Chloride, Dietary*; Aorta, Thoracic/Aorta, Thoracic/Aorta, Thoracic/*drug effects

  • Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2020 Sep 26; Vol. 19 (1), pp. 149. Date of Electronic Publication: 2020 Sep 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium:

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Academic Journal

Benzofuroxan derivatives N-Br and N-I induce intrinsic apoptosis in melanoma cells by regulating AKT/BIM signaling and display anti metastatic activity in vivo.

  • Authors : Farias CF; Experimental Oncology Unit (UNONEX), Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo, Rua Botucatu 862, 8 andar, São Paulo, SP, 04023-062, Brazil. .; Massaoka MH

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*metabolism ; Benzoxazoles/Benzoxazoles/Benzoxazoles/*chemistry

  • Source: BMC cancer [BMC Cancer] 2015 Oct 27; Vol. 15, pp. 807. Date of Electronic Publication: 2015 Oct 27.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium:

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  • 1-10 of  33 results for ""Benzoxazoles""