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Academic Journal

Impact of Amino Acid Substitutions in Region II and Helix K of Herpes Simplex Virus 1 and Human Cytomegalovirus DNA Polymerases on Resistance to Foscarnet.

  • Authors : Zarrouk K; Research Center in Infectious Diseases, CHU de Québec-Laval University, Quebec City, Quebec, Canada.; Zhu X

Subjects: Herpesvirus 1, Human*/Herpesvirus 1, Human*/Herpesvirus 1, Human*/genetics; Amino Acid Substitution ; Antiviral Agents/Antiviral Agents/Antiviral Agents/pharmacology

  • Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Jun 17; Vol. 65 (7), pp. e0039021. Date of Electronic Publication: 2021 Jun 17.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model:

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Academic Journal

An Early Microglial Response Is Needed To Efficiently Control Herpes Simplex Virus Encephalitis.

  • Authors : Uyar O; Research Center in Infectious Diseases, CHU de Québec-Laval University Research Center and Department of Microbiology, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada.; Laflamme N

Subjects: Encephalitis, Herpes Simplex/Encephalitis, Herpes Simplex/Encephalitis, Herpes Simplex/*metabolism ; Herpesvirus 1, Human/Herpesvirus 1, Human/Herpesvirus 1, Human/*metabolism ; Macrophage Colony-Stimulating Factor/Macrophage Colony-Stimulating Factor/Macrophage Colony-Stimulating Factor/*metabolism

  • Source: Journal of virology [J Virol] 2020 Nov 09; Vol. 94 (23). Date of Electronic Publication: 2020 Nov 09 (Print Publication: 2020).Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model:

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Academic Journal

Hypersusceptibility of Human Cytomegalovirus to Foscarnet Induced by Mutations in Helices K and P of the Viral DNA Polymerase.

  • Authors : Zarrouk K; Research Center in Infectious Diseases, CHU de Québec-Laval University, Quebec City, Quebec, Canada.; Pham VD

Subjects: Antiviral Agents/Antiviral Agents/Antiviral Agents/*pharmacology ; Cytomegalovirus/Cytomegalovirus/Cytomegalovirus/*drug effects ; Cytomegalovirus/Cytomegalovirus/Cytomegalovirus/*genetics

  • Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Mar 24; Vol. 64 (4). Date of Electronic Publication: 2020 Mar 24 (Print Publication: 2020).Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model:

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Academic Journal

Immunomodulatory Strategies in Herpes Simplex Virus Encephalitis.

  • Authors : Piret J; Research Center in Infectious Diseases, CHU de Quebec-Laval University, Quebec City, Canada.; Boivin G

Subjects: Immunomodulation*; Encephalitis, Herpes Simplex/Encephalitis, Herpes Simplex/Encephalitis, Herpes Simplex/*diagnosis ; Encephalitis, Herpes Simplex/Encephalitis, Herpes Simplex/Encephalitis, Herpes Simplex/*immunology

  • Source: Clinical microbiology reviews [Clin Microbiol Rev] 2020 Feb 12; Vol. 33 (2). Date of Electronic Publication: 2020 Feb 12 (Print Publication: 2020).Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 8807282 Publication Model:

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Academic Journal

Drug Susceptibility and Replicative Capacity of Multidrug-Resistant Recombinant Human Cytomegalovirus Harboring Mutations in UL56 and UL54 Genes.

  • Authors : Piret J; Research Center in Infectious Diseases, CHU of Quebec and Laval University, Quebec City, Quebec, Canada.; Goyette N

Subjects: Antiviral Agents/Antiviral Agents/Antiviral Agents/*pharmacology ; Cytomegalovirus/Cytomegalovirus/Cytomegalovirus/*drug effects ; DNA-Directed DNA Polymerase/DNA-Directed DNA Polymerase/DNA-Directed DNA Polymerase/*genetics

  • Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2017 Oct 24; Vol. 61 (11). Date of Electronic Publication: 2017 Oct 24 (Print Publication: 2017).Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model:

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Academic Journal

Novel Method Based on Real-Time Cell Analysis for Drug Susceptibility Testing of Herpes Simplex Virus and Human Cytomegalovirus.

  • Authors : Piret J; Research Center in Infectious Diseases, CHU of Quebec and Laval University, Quebec City, Quebec, CanadaMemorial Sloan-Kettering Cancer Center.; Goyette N

Subjects: Antiviral Agents/Antiviral Agents/Antiviral Agents/*pharmacology ; Cytomegalovirus/Cytomegalovirus/Cytomegalovirus/*drug effects ; Microbial Sensitivity Tests/Microbial Sensitivity Tests/Microbial Sensitivity Tests/*methods

  • Source: Journal of clinical microbiology [J Clin Microbiol] 2016 Aug; Vol. 54 (8), pp. 2120-7. Date of Electronic Publication: 2016 Jun 01.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model:

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Academic Journal

Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility.

  • Authors : Piret J; Research Center in Infectious Diseases, CHU de Québec and Laval University, Quebec City, QC, Canada.; Goyette N

Subjects: Models, Molecular*; Cytomegalovirus/Cytomegalovirus/Cytomegalovirus/*enzymology ; DNA-Directed DNA Polymerase/DNA-Directed DNA Polymerase/DNA-Directed DNA Polymerase/*genetics

  • Source: Journal of virology [J Virol] 2015 Apr; Vol. 89 (8), pp. 4636-44. Date of Electronic Publication: 2015 Feb 11.Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model:

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Academic Journal

Characterization of multiple cytomegalovirus drug resistance mutations detected in a hematopoietic stem cell transplant recipient by recombinant phenotyping.

  • Authors : Drouot E; Research Center in Infectious Diseases, CHU de Québec and Université Laval, Québec, QC, Canada.; Piret J

Subjects: Drug Resistance, Viral* ; Hematopoietic Stem Cell Transplantation* ; Mutation, Missense*

  • Source: Journal of clinical microbiology [J Clin Microbiol] 2014 Nov; Vol. 52 (11), pp. 4043-6. Date of Electronic Publication: 2014 Aug 20.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model:

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Academic Journal

Two novel proteins of cyanophage Syn5 compose its unusual horn structure.

Subjects: Bacteriophages/Bacteriophages/Bacteriophages/*genetics ; Capsid Proteins/Capsid Proteins/Capsid Proteins/*metabolism ; Synechococcus/Synechococcus/Synechococcus/*virology

  • Source: Journal of virology [J Virol] 2014 Feb; Vol. 88 (4), pp. 2047-55. Date of Electronic Publication: 2013 Dec 04.Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model:

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Academic Journal

Novel method based on "en passant" mutagenesis coupled with a gaussia luciferase reporter assay for studying the combined effects of human cytomegalovirus mutations.

  • Authors : Drouot E; Research Center in Infectious Diseases, Laval University, Quebec City, Quebec, Canada.; Piret J

Subjects: Genes, Reporter* ; Mutagenesis* ; Mutation*

  • Source: Journal of clinical microbiology [J Clin Microbiol] 2013 Oct; Vol. 51 (10), pp. 3216-24. Date of Electronic Publication: 2013 Jul 17.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model:

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