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Academic Journal

Deficiency of Src family kinases Fgr and Hck results in activation of erythrocyte K/Cl cotransport.

Subjects: Symporters*; Chlorides/Chlorides/Chlorides/*metabolism ; Erythrocytes/Erythrocytes/Erythrocytes/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 1997 Jan 15; Vol. 99 (2), pp. 220-7.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases.

  • Authors : Katsumoto TR; Division of Rheumatology and Rosalind Russell Medical Research Center for Arthritis, University of California San Francisco (UCSF), San Francisco, California, USA.; Kudo M

Subjects: Asthma/Asthma/Asthma/*pathology ; Lung/Lung/Lung/*pathology ; src-Family Kinases/src-Family Kinases/src-Family Kinases/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2013 May; Vol. 123 (5), pp. 2037-48. Date of Electronic Publication: 2013 Apr 01.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Fgr contributes to hemorrhage-induced thalamic pain by activating NF-κB/ERK1/2 pathways.

  • Authors : Huang T; Department of Anesthesiology.; Fu G

Subjects: Hemorrhagic Stroke/Hemorrhagic Stroke/Hemorrhagic Stroke/*genetics ; Hyperalgesia/Hyperalgesia/Hyperalgesia/*genetics ; Neuralgia/Neuralgia/Neuralgia/*genetics

  • Source: JCI insight [JCI Insight] 2020 Oct 15; Vol. 5 (20). Date of Electronic Publication: 2020 Oct 15.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Combined SFK/MEK inhibition prevents metastatic outgrowth of dormant tumor cells.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Benzimidazoles/Benzimidazoles/Benzimidazoles/*pharmacology ; Benzodioxoles/Benzodioxoles/Benzodioxoles/*pharmacology

  • Source: The Journal of clinical investigation [J Clin Invest] 2014 Jan; Vol. 124 (1), pp. 156-68. Date of Electronic Publication: 2013 Dec 09.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

LYN-activating mutations mediate antiestrogen resistance in estrogen receptor-positive breast cancer.

Subjects: Mutation, Missense*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*genetics

  • Source: The Journal of clinical investigation [J Clin Invest] 2014 Dec; Vol. 124 (12), pp. 5490-502. Date of Electronic Publication: 2014 Nov 17.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction.

  • Authors : Weis S; Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA.; Shintani S

Subjects: Cadherins/Cadherins/Cadherins/*metabolism ; Edema/Edema/Edema/*metabolism ; Myocardial Infarction/Myocardial Infarction/Myocardial Infarction/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2004 Mar; Vol. 113 (6), pp. 885-94.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Src promotes estrogen-dependent estrogen receptor alpha proteolysis in human breast cancer.

  • Authors : Chu I; Braman Family Breast Cancer Institute and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.; Arnaout A

Subjects: Gene Expression Regulation, Neoplastic*/Gene Expression Regulation, Neoplastic*/Gene Expression Regulation, Neoplastic*/drug effects ; Protein Processing, Post-Translational*/Protein Processing, Post-Translational*/Protein Processing, Post-Translational*/drug effects; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2007 Aug; Vol. 117 (8), pp. 2205-15.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.

  • Authors : Contri A; Department of Clinical and Experimental Medicine, Clinical Immunology Branch, Padua University School of Medicine, Padua, Italy.; Brunati AM

Subjects: Apoptosis* ; Gene Expression Regulation, Leukemic*/Gene Expression Regulation, Leukemic*/Gene Expression Regulation, Leukemic*/drug effects; B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2005 Feb; Vol. 115 (2), pp. 369-78.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer.

Subjects: Head and Neck Neoplasms/Head and Neck Neoplasms/Head and Neck Neoplasms/*drug therapy ; Squamous Cell Carcinoma of Head and Neck/Squamous Cell Carcinoma of Head and Neck/Squamous Cell Carcinoma of Head and Neck/*drug therapy ; src-Family Kinases/src-Family Kinases/src-Family Kinases/*antagonists & inhibitors

  • Source: JCI insight [JCI Insight] 2017 Mar 23; Vol. 2 (6), pp. e90449. Date of Electronic Publication: 2017 Mar 23.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.

Subjects: Autoimmunity*; Transcription Factors/Transcription Factors/Transcription Factors/*physiology ; src-Family Kinases/src-Family Kinases/src-Family Kinases/*physiology

  • Source: The Journal of clinical investigation [J Clin Invest] 2016 Oct 03; Vol. 126 (10), pp. 3758-3771. Date of Electronic Publication: 2016 Aug 29.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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