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  • 1-10 of  205 results for ""Ubiquitin-Protein Ligases""

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Academic Journal

Parkin paves the path to antitumor immunity: Expanding Parkin's role as a tumor suppressor.

Subjects: Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/immunology ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Nov 15; Vol. 134 (22). Date of Electronic Publication: 2024 Nov 15.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Pharmacologic or genetic interference with atrogene signaling protects against glucocorticoid-induced musculoskeletal and cardiac disease.

  • Authors : Sato AY; Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Subjects: Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics ; Glucocorticoids*/Glucocorticoids*/Glucocorticoids*/pharmacology

  • Source: JCI insight [JCI Insight] 2024 Nov 08; Vol. 9 (21). Date of Electronic Publication: 2024 Nov 08.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Purkinje cell-specific deficiency in SEL1L-hrd1 endoplasmic reticulum-associated degradation causes progressive cerebellar ataxia in mice.

  • Authors : Torres M; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.; Pederson B

Subjects: Purkinje Cells*/Purkinje Cells*/Purkinje Cells*/metabolism ; Purkinje Cells*/Purkinje Cells*/Purkinje Cells*/pathology ; Cerebellar Ataxia*/Cerebellar Ataxia*/Cerebellar Ataxia*/genetics

  • Source: JCI insight [JCI Insight] 2024 Nov 08; Vol. 9 (21). Date of Electronic Publication: 2024 Nov 08.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Deficiency of parkin causes neurodegeneration and accumulation of pathological α-synuclein in monkey models.

  • Authors : Han R; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Key Laboratory of Non-human Primate Research, GHM Institute of CNS Regeneration, Jinan University, Guangzhou, China.; Wang Q

Subjects: Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/deficiency

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Oct 15; Vol. 134 (20). Date of Electronic Publication: 2024 Oct 15.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Reversible cold-induced lens opacity in a hibernator reveals a molecular target for treating cataracts.

  • Authors : Yang H; Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Ping X

Subjects: Cataract*/Cataract*/Cataract*/genetics ; Cataract*/Cataract*/Cataract*/pathology ; Cataract*/Cataract*/Cataract*/metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Sep 17; Vol. 134 (18). Date of Electronic Publication: 2024 Sep 17.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Parkin activates innate immunity and promotes antitumor immune responses.

  • Authors : Perego M; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania, USA.; Yeon M

Subjects: Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/immunology ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Aug 30; Vol. 134 (22). Date of Electronic Publication: 2024 Aug 30.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Rare genetic variants provide a mechanistic basis for immune imbalance in IgG4-related disease.

Subjects: Immunoglobulin G4-Related Disease*/Immunoglobulin G4-Related Disease*/Immunoglobulin G4-Related Disease*/genetics ; Immunoglobulin G4-Related Disease*/Immunoglobulin G4-Related Disease*/Immunoglobulin G4-Related Disease*/immunology ; Immunoglobulin G4-Related Disease*/Immunoglobulin G4-Related Disease*/Immunoglobulin G4-Related Disease*/pathology

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Aug 15; Vol. 134 (16). Date of Electronic Publication: 2024 Aug 15.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

IKZF1 and UBR4 gene variants drive autoimmunity and Th2 polarization in IgG4-related disease.

Subjects: Autoimmunity*/Autoimmunity*/Autoimmunity*/genetics ; Ikaros Transcription Factor*/Ikaros Transcription Factor*/Ikaros Transcription Factor*/genetics ; Ikaros Transcription Factor*/Ikaros Transcription Factor*/Ikaros Transcription Factor*/immunology

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Jun 13; Vol. 134 (16). Date of Electronic Publication: 2024 Jun 13.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

ADAM17 variant causes hair loss via ubiquitin ligase TRIM47-mediated degradation.

  • Authors : Wang X; Department of Dermatology, Xinhua Hospital, and.; Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Subjects: ADAM17 Protein*/ADAM17 Protein*/ADAM17 Protein*/metabolism ; ADAM17 Protein*/ADAM17 Protein*/ADAM17 Protein*/genetics ; Alopecia*/Alopecia*/Alopecia*/genetics

  • Source: JCI insight [JCI Insight] 2024 May 21; Vol. 9 (13). Date of Electronic Publication: 2024 May 21.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Hypomorphic human SEL1L and HRD1 variants uncouple multilayered ER-associated degradation machinery.

Subjects: Endoplasmic Reticulum-Associated Degradation* ; Proteins*/Proteins*/Proteins*/genetics ; Proteins*/Proteins*/Proteins*/metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Jan 16; Vol. 134 (2). Date of Electronic Publication: 2024 Jan 16.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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  • 1-10 of  205 results for ""Ubiquitin-Protein Ligases""