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Publisher : american society for clinical investigation

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Academic Journal

Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice.

Authors : Viret, Christophe^1,2,3; Stéphane Leung-Theung-Long^1,2,3; Serre, Laurent^1,2,3

Subjects: *SERINE proteinases; *EPITHELIAL cells; *DIABETES

Source: Journal of Clinical Investigation. May2011, Vol. 121 Issue 5, p1810-1821. 10p. 9 Graphs.

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Academic Journal

Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2.

Authors : Selander, Barbro¹; Mårtensson, Ulla¹; Weintraub, Andrej²

Subjects: *LECTINS; *SERINE proteinases; *SERUM

Source: Journal of Clinical Investigation. May2006, Vol. 116 Issue 5, p1425-1434. 10p. 1 Black and White Photograph, 2 Charts, 7 Graphs.

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Academic Journal

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells.

Authors : West, Kip A.; Brognard, John; Clark, Amy S.

Subjects: *SERINE proteinases; *PROTEIN kinases; *NICOTINE

Source: Journal of Clinical Investigation. 1/1/2003, Vol. 111 Issue 1, p81-90. 10p. 1 Color Photograph, 4 Charts, 3 Graphs.

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Academic Journal

Overexpression of the serpin megsin induces progressive mesangial cell proliferation and expansion.

Authors : Miyata, Toshio; Inagi, Reiko; Nangaku, Masaomi

Subjects: *SERINE proteinases; *CELL proliferation; *IMMUNE complexes

Source: Journal of Clinical Investigation. 3/1/2002, Vol. 109 Issue 5, p585. 9p. 4 Color Photographs, 5 Diagrams, 3 Graphs.

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Academic Journal

Structure-based phylogeny identifies avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice.

Authors : Young Joo Sun; Velez, Gabriel; Parsons, Dylan E.

Subjects: COVID-19; SARS-CoV-2; TRYPSIN

Source: Journal of Clinical Investigation. 5/17/2021, Vol. 131 Issue 10, p1-13. 13p. 1 Diagram, 5 Graphs.

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Academic Journal

Serine protease activity contributes to control of Mycobacterium tuberculosis in hypoxic lung granulomas in mice.

Authors : Reece, Stephen T.¹ ; Loddenkemper, Christoph²; Askew, David J.^3,4

Subjects: *SERINE proteinases; *MYCOBACTERIUM tuberculosis; *GRANULOMA

Source: Journal of Clinical Investigation. Sep2010, Vol. 120 Issue 9, p3365-3376. 12p. 1 Color Photograph, 1 Chart, 5 Graphs.

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Academic Journal

Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus.

Authors : Echeverry, Ramiro¹; Jialing Wu^1,2; Haile, Woldeab B.¹

Subjects: *SERINE proteinases; *PLASMINOGEN activators; *FIBRINOLYTIC agents

Source: Journal of Clinical Investigation. Jun2010, Vol. 120 Issue 6, p2194-2205. 12p. 2 Color Photographs, 7 Graphs.

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Academic Journal

Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity.

Authors : Chien, Jeremy¹; Aletti, Giovanni¹; Baldi, Alfonso²

Subjects: *SERINE proteinases; *DRUG therapy; *CANCER

Source: Journal of Clinical Investigation. Jul2006, Vol. 116 Issue 7, p1994-2004. 11p. 2 Color Photographs, 4 Black and White Photographs, 2 Charts, 6 Graphs.

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Academic Journal

Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo.

Authors : Qi Ling, Andrew T.¹; Jacovina, Arunkumar¹; Deora, Maria¹

Subjects: *PLASMINOGEN; *SERINE proteinases; *MICE

Source: Journal of Clinical Investigation. Jan2004, Vol. 113 Issue 1, p38-48. 11p. 7 Black and White Photographs, 6 Graphs.

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Academic Journal

De novo monoallelic Reelin missense variants cause dominant neuronal migration disorders via a dominant-negative mechanism.

Authors : Riva M; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris, INSERM U1266, and.; Université Paris Cité, Imagine Institute, Team Genetics and Development of the Cerebral Cortex, Paris, France.

Subjects: Reelin Protein* ; Mutation, Missense* ; Extracellular Matrix Proteins*/Extracellular Matrix Proteins*/Extracellular Matrix Proteins*/genetics

Source: The Journal of clinical investigation [J Clin Invest] 2024 Jul 09; Vol. 134 (16). Date of Electronic Publication: 2024 Jul 09.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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