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Academic Journal

Splicing factor SRSF6 mediates pleural fibrosis.

  • Authors : Liang LM; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Xiong L

Subjects: Phosphoproteins*/Phosphoproteins*/Phosphoproteins*/genetics ; Phosphoproteins*/Phosphoproteins*/Phosphoproteins*/metabolism ; Serine-Arginine Splicing Factors*/Serine-Arginine Splicing Factors*/Serine-Arginine Splicing Factors*/genetics

  • Source: JCI insight [JCI Insight] 2021 May 24; Vol. 6 (10). Date of Electronic Publication: 2021 May 24.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Mutant SF3B1 promotes AKT- and NF-κB-driven mammary tumorigenesis.

  • Authors : Liu B; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Liu Z

Subjects: Mutation*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2021 Jan 04; Vol. 131 (1).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation.

  • Authors : Dalton WB; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, and.; Helmenstine E

Subjects: Cellular Reprogramming* ; Mutation* ; Neoplasms*/Neoplasms*/Neoplasms*/diet therapy

  • Source: The Journal of clinical investigation [J Clin Invest] 2019 Aug 08; Vol. 129 (11), pp. 4708-4723. Date of Electronic Publication: 2019 Aug 08.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium.

  • Authors : Schaefer N; National Jewish Health, Denver, Colorado, USA.; Li X

Subjects: Asthma/Asthma/Asthma/*genetics ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*immunology ; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*immunology

  • Source: JCI insight [JCI Insight] 2019 Apr 18; Vol. 4 (8). Date of Electronic Publication: 2019 Apr 18 (Print Publication: 2019).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis.

  • Authors : Chen M; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School, Boston, Massachusetts, USA.; Zhang J

Subjects: Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/biosynthesis ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/genetics ; Cell Transformation, Neoplastic*/Cell Transformation, Neoplastic*/Cell Transformation, Neoplastic*/genetics

  • Source: The Journal of clinical investigation [J Clin Invest] 2019 Jan 02; Vol. 129 (1), pp. 215-222. Date of Electronic Publication: 2018 Nov 26.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

IFI16 filament formation in salivary epithelial cells shapes the anti-IFI16 immune response in Sjögren's syndrome.

Subjects: Autoantibodies*; Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*immunology

  • Source: JCI insight [JCI Insight] 2018 Sep 20; Vol. 3 (18). Date of Electronic Publication: 2018 Sep 20 (Print Publication: 2018).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Inherited p40phox deficiency differs from classic chronic granulomatous disease.

  • Authors : van de Geer A; Department of Blood Cell Research, Sanquin Research, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Nieto-Patlán A

Subjects: Loss of Function Mutation*; Granulomatous Disease, Chronic/Granulomatous Disease, Chronic/Granulomatous Disease, Chronic/*genetics ; Phosphoproteins/Phosphoproteins/Phosphoproteins/*deficiency

  • Source: The Journal of clinical investigation [J Clin Invest] 2018 Aug 31; Vol. 128 (9), pp. 3957-3975. Date of Electronic Publication: 2018 Aug 06.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Active epithelial Hippo signaling in idiopathic pulmonary fibrosis.

  • Authors : Gokey JJ; Division of Neonatology, Perinatal and Pulmonary Biology, and.; Sridharan A

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism

  • Source: JCI insight [JCI Insight] 2018 Mar 22; Vol. 3 (6). Date of Electronic Publication: 2018 Mar 22.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction.

Subjects: Immune Tolerance*; Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*immunology ; Myocardial Infarction/Myocardial Infarction/Myocardial Infarction/*immunology

  • Source: The Journal of clinical investigation [J Clin Invest] 2017 Mar 01; Vol. 127 (3), pp. 899-911. Date of Electronic Publication: 2017 Feb 06.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodeling.

  • Authors : Wood AJ; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, United Kingdom.; Vassallo AM

Subjects: Critical Illness* ; Phagocytosis*; Complement C5a/Complement C5a/Complement C5a/*metabolism

  • Source: JCI insight [JCI Insight] 2020 Aug 06; Vol. 5 (15). Date of Electronic Publication: 2020 Aug 06.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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