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Academic Journal

Proton-activated chloride channel increases endplate porosity and pain in a mouse spine degeneration model.

  • Authors : Xue P; Center for Musculoskeletal Research, Department of Orthopedic Surgery.; Zhang W

Subjects: Osteoclasts*/Osteoclasts*/Osteoclasts*/metabolism ; Osteoclasts*/Osteoclasts*/Osteoclasts*/pathology ; Mice, Knockout*

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Aug 28; Vol. 134 (20). Date of Electronic Publication: 2024 Aug 28.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Calcineurin regulates aldosterone production via dephosphorylation of NFATC4.

  • Authors : Berber M; Institute of Anatomy, University of Zurich, Switzerland.; Swiss National Centre for Competence in Research 'Kidney Control of Homeostasis' (NCCR Kidney.CH), Zurich, Switzerland.

Subjects: Aldosterone*/Aldosterone*/Aldosterone*/metabolism ; Calcineurin*/Calcineurin*/Calcineurin*/metabolism ; Hyperkalemia*

  • Source: JCI insight [JCI Insight] 2023 Jul 24; Vol. 8 (14). Date of Electronic Publication: 2023 Jul 24.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation.

  • Authors : Simonett SP; Biochemistry Department, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Shin S

Subjects: Cell Proliferation* ; Gene Expression Regulation* ; Response Elements*

  • Source: The Journal of clinical investigation [J Clin Invest] 2021 Nov 01; Vol. 131 (21).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Calcineurin inhibitors suppress acute graft-versus-host disease via NFAT-independent inhibition of T cell receptor signaling.

Subjects: CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*immunology ; Calcineurin Inhibitors/Calcineurin Inhibitors/Calcineurin Inhibitors/*pharmacology ; Cyclosporine/Cyclosporine/Cyclosporine/*pharmacology

  • Source: The Journal of clinical investigation [J Clin Invest] 2021 Jun 01; Vol. 131 (11).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Calcineurin inhibitors target Lck activation in graft-versus-host disease.

Subjects: Calcineurin Inhibitors*/Calcineurin Inhibitors*/Calcineurin Inhibitors*/pharmacology ; Graft vs Host Disease*; Calcineurin

  • Source: The Journal of clinical investigation [J Clin Invest] 2021 Jun 01; Vol. 131 (11).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer.

  • Authors : Cole AJ; Department of Internal Medicine and Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Iyengar M

Subjects: Drug Resistance, Neoplasm* ; Resting Phase, Cell Cycle*; NFATC Transcription Factors/NFATC Transcription Factors/NFATC Transcription Factors/*metabolism

  • Source: JCI insight [JCI Insight] 2020 Apr 09; Vol. 5 (7). Date of Electronic Publication: 2020 Apr 09.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

CD14 and NFAT mediate lipopolysaccharide-induced skin edema formation in mice.

  • Authors : Zanoni I; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.; Ostuni R

Subjects: Dendritic Cells/Dendritic Cells/Dendritic Cells/*metabolism ; Edema/Edema/Edema/*metabolism ; Lipopolysaccharide Receptors/Lipopolysaccharide Receptors/Lipopolysaccharide Receptors/*physiology

  • Source: The Journal of clinical investigation [J Clin Invest] 2012 May; Vol. 122 (5), pp. 1747-57. Date of Electronic Publication: 2012 Apr 02.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.

  • Authors : Bécart S; Division of Cell Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.; Charvet C

Subjects: Calcium Signaling/Calcium Signaling/Calcium Signaling/*immunology ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*immunology ; NFATC Transcription Factors/NFATC Transcription Factors/NFATC Transcription Factors/*immunology

  • Source: The Journal of clinical investigation [J Clin Invest] 2007 Aug; Vol. 117 (8), pp. 2164-75.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Calcineurin/Nfat signaling is required for perinatal lung maturation and function.

  • Authors : Davé V; Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA. ; Childs T

Subjects: Calcineurin/Calcineurin/Calcineurin/*genetics ; Lung/Lung/Lung/*metabolism ; NFATC Transcription Factors/NFATC Transcription Factors/NFATC Transcription Factors/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2006 Oct; Vol. 116 (10), pp. 2597-609. Date of Electronic Publication: 2006 Sep 21.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Gα13 ablation reprograms myofibers to oxidative phenotype and enhances whole-body metabolism.

  • Authors : Koo JH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.; Kim TH

Subjects: Energy Metabolism*; Fatty Liver/Fatty Liver/Fatty Liver/*metabolism ; GTP-Binding Protein alpha Subunits, G12-G13/GTP-Binding Protein alpha Subunits, G12-G13/GTP-Binding Protein alpha Subunits, G12-G13/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2017 Oct 02; Vol. 127 (10), pp. 3845-3860. Date of Electronic Publication: 2017 Sep 18.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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