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Publisher : american society for clinical investigation
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Academic Journal

Locus coeruleus activity while awake is associated with REM sleep quality in older individuals.

  • Authors : Koshmanova E; Sleep and Chronobiology Lab, GIGA-Institute, CRC-In Vivo Imaging Unit, University of Liège (ULiège), Liège, Belgium.; Berger A

Subjects: Sleep, REM* ; Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/diagnostic imaging ; Locus Coeruleus*/Locus Coeruleus*/Locus Coeruleus*/physiology

  • Source: JCI insight [JCI Insight] 2023 Oct 23; Vol. 8 (20). Date of Electronic Publication: 2023 Oct 23.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.

  • Authors : Kang SS; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.; Liu X

Subjects: Adrenergic Neurons/Adrenergic Neurons/Adrenergic Neurons/*metabolism ; Aldehydes/Aldehydes/Aldehydes/*metabolism ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2020 Jan 02; Vol. 130 (1), pp. 422-437.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Antisense technology reveals the alpha2A adrenoceptor to be the subtype mediating the hypnotic response to the highly selective agonist, dexmedetomidine, in the locus coeruleus of the rat.

  • Authors : Mizobe T; Anesthesiology Service, Veterans Affairs Palo Alto Health Care System, California, 94304 USA.; Maghsoudi K

Subjects: Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/*pharmacology ; Hypnotics and Sedatives/Hypnotics and Sedatives/Hypnotics and Sedatives/*pharmacology ; Imidazoles/Imidazoles/Imidazoles/*pharmacology

  • Source: The Journal of clinical investigation [J Clin Invest] 1996 Sep 01; Vol. 98 (5), pp. 1076-80.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Editorial & Opinion

Making sense out of antisense for the study of drug receptors.

Subjects: Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/Adrenergic alpha-Agonists/*pharmacology ; Hypnotics and Sedatives/Hypnotics and Sedatives/Hypnotics and Sedatives/*pharmacology ; Imidazoles/Imidazoles/Imidazoles/*pharmacology

  • Source: The Journal of clinical investigation [J Clin Invest] 1996 Sep 01; Vol. 98 (5), pp. 1074-5.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Xylazine induces dopamine release and augments the effects of fentanyl.

Subjects: DOPAMINE receptors; FENTANYL; XYLAZINE

  • Source: Journal of Clinical Investigation. 11/15/2024, Vol. 134 Issue 22, p1-3. 3p.

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Academic Journal

Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.

Subjects: LOCUS coeruleus; NORADRENALINE; NORADRENERGIC neurons

  • Source: Journal of Clinical Investigation. Jan2020, Vol. 130 Issue 1, p422-437. 16p.

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Academic Journal

Gβγ-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity.

Subjects: WHITE adipose tissue; WESTERN diet; FAT cells

  • Source: Journal of Clinical Investigation. 10/2/2023, Vol. 133 Issue 19, p1-19. 19p.

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Academic Journal

A neuronal action of sirtuin 1 suppresses bone mass in young and aging mice.

Subjects: SEROTONIN uptake inhibitors; TRYPTOPHAN hydroxylase; SYMPATHETIC nervous system

  • Source: Journal of Clinical Investigation. 12/1/2022, Vol. 132 Issue 23, p1-13. 13p.

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Academic Journal

Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.

Subjects: OREXINS; WAKEFULNESS; NARCOLEPSY

  • Source: Journal of Clinical Investigation. Feb2014, Vol. 124 Issue 2, p604-616. 13p. 2 Color Photographs, 1 Black and White Photograph, 1 Chart, 3 Graphs.

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Academic Journal

Early brainstem [18F]THK5351 uptake is linked to cortical hyperexcitability in healthy aging.

Subjects: Aminopyridines/Aminopyridines/Aminopyridines/*pharmacokinetics ; Brain Stem/Brain Stem/Brain Stem/*diagnostic imaging ; Brain Stem/Brain Stem/Brain Stem/*metabolism

  • Source: JCI insight [JCI Insight] 2021 Jan 25; Vol. 6 (2). Date of Electronic Publication: 2021 Jan 25.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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  • 1-10 of  106 results for ""LOCUS coeruleus""