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Publisher : american society for clinical investigation
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Academic Journal

Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90.

  • Authors : Kang BH; Department of Cancer Biology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA.; Plescia J

Subjects: Combinatorial Chemistry Techniques* ; Drug Design*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use

  • Source: The Journal of clinical investigation [J Clin Invest] 2009 Mar; Vol. 119 (3), pp. 454-64. Date of Electronic Publication: 2009 Feb 23.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes.

  • Authors : O'Sullivan JF; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Charles Perkins Centre and Heart Research Institute, The University of Sydney, Sydney, Australia.

Subjects: Adipose Tissue/Adipose Tissue/Adipose Tissue/*metabolism ; Diabetes Mellitus/Diabetes Mellitus/Diabetes Mellitus/*blood ; Guanidines/Guanidines/Guanidines/*blood

  • Source: The Journal of clinical investigation [J Clin Invest] 2017 Dec 01; Vol. 127 (12), pp. 4394-4402. Date of Electronic Publication: 2017 Oct 30.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors.

Subjects: Extracellular Signal-Regulated MAP Kinases/Extracellular Signal-Regulated MAP Kinases/Extracellular Signal-Regulated MAP Kinases/*antagonists & inhibitors ; Guanidines/Guanidines/Guanidines/*pharmacology ; Lactams, Macrocyclic/Lactams, Macrocyclic/Lactams, Macrocyclic/*pharmacology

  • Source: The Journal of clinical investigation [J Clin Invest] 2016 May 02; Vol. 126 (5), pp. 1834-56. Date of Electronic Publication: 2016 Apr 04.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.

  • Authors : Cross AH; Department of Neurology, Washington University School of Medicine, Saint Louis, Missouri 63110.; Misko TP

Subjects: Amino Acid Oxidoreductases/Amino Acid Oxidoreductases/Amino Acid Oxidoreductases/*antagonists & inhibitors ; Encephalomyelitis, Autoimmune, Experimental/Encephalomyelitis, Autoimmune, Experimental/Encephalomyelitis, Autoimmune, Experimental/*prevention & control ; Guanidines/Guanidines/Guanidines/*pharmacology

  • Source: The Journal of clinical investigation [J Clin Invest] 1994 Jun; Vol. 93 (6), pp. 2684-90.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Aminoguanidine treatment increases elasticity and decreases fluid filtration of large arteries from diabetic rats.

Subjects: Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/*physiopathology ; Guanidines/Guanidines/Guanidines/*pharmacology ; Vascular Resistance/Vascular Resistance/Vascular Resistance/*drug effects

  • Source: The Journal of clinical investigation [J Clin Invest] 1993 Sep; Vol. 92 (3), pp. 1407-11.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Homologous upregulation of human arterial alpha-adrenergic responses by guanadrel.

Subjects: Guanidines/Guanidines/Guanidines/*pharmacology ; Sympathomimetics/Sympathomimetics/Sympathomimetics/*pharmacology ; Up-Regulation/Up-Regulation/Up-Regulation/*drug effects

  • Source: The Journal of clinical investigation [J Clin Invest] 1993 Apr; Vol. 91 (4), pp. 1429-35.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Reversal of secondary hyperparathyroidism by cimetidine in chronically uremic dogs.

Subjects: Cimetidine/Cimetidine/Cimetidine/*therapeutic use ; Guanidines/Guanidines/Guanidines/*therapeutic use ; Hyperparathyroidism, Secondary/Hyperparathyroidism, Secondary/Hyperparathyroidism, Secondary/*drug therapy

  • Source: The Journal of clinical investigation [J Clin Invest] 1981 Jun; Vol. 67 (6), pp. 1753-60.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Potential applications for biguanides in oncology.

Subjects: *BIGUANIDE; *GUANIDINES; *ONCOLOGY

  • Source: Journal of Clinical Investigation. Sep2013, Vol. 123 Issue 9, p3693-3700. 8p. 2 Diagrams.

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Academic Journal

Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes.

Subjects: VALERIC acid; BIOMARKERS; FATTY liver

  • Source: Journal of Clinical Investigation. Dec2017, Vol. 127 Issue 12, p4394-4402. 9p.

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Academic Journal

Dengue virus-elicited tryptase induces endothelial permeability and shock.

  • Authors : Rathore AP; Program in Emerging Infectious Diseases, Duke-National University of Singapore, Singapore.; Mantri CK

Subjects: Capillary Permeability*; Dengue/Dengue/Dengue/*enzymology ; Dengue Virus/Dengue Virus/Dengue Virus/*metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2019 Jul 02; Vol. 129 (10), pp. 4180-4193. Date of Electronic Publication: 2019 Jul 02.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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  • 1-10 of  50 results for ""GUANIDINES""