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Academic Journal

Cancer neoepitopes viewed through negative selection and peripheral tolerance: a new path to cancer vaccines.

Subjects: Cancer Vaccines* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/therapy

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Mar 01; Vol. 134 (5). Date of Electronic Publication: 2024 Mar 01.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Phosphodiesterase-5 inhibition collaborates with vaccine-based immunotherapy to reprogram myeloid cells in pancreatic ductal adenocarcinoma.

  • Authors : Gross NE; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center.; Zhang Z

Subjects: Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/immunology ; Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/therapy ; Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/drug therapy

  • Source: JCI insight [JCI Insight] 2024 Aug 06; Vol. 9 (18). Date of Electronic Publication: 2024 Aug 06.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

CD4 T cell-activating neoantigens enhance personalized cancer vaccine efficacy.

  • Authors : Huff AL; Johns Hopkins Convergence Institute and.; Johns Hopkins Bloomberg Kimmel Institute for Immunotherapy, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Subjects: Cancer Vaccines* ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism; Mice

  • Source: JCI insight [JCI Insight] 2023 Dec 08; Vol. 8 (23). Date of Electronic Publication: 2023 Dec 08.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model:

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Academic Journal

Combination of AFP vaccine and immune checkpoint inhibitors slows hepatocellular carcinoma progression in preclinical models.

  • Authors : Lu X; Department of Biliary-Pancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.; Deng S

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/metabolism ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/metabolism ; Cancer Vaccines*/Cancer Vaccines*/Cancer Vaccines*/therapeutic use

  • Source: The Journal of clinical investigation [J Clin Invest] 2023 Jun 01; Vol. 133 (11). Date of Electronic Publication: 2023 Jun 01.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Next-generation antigen-presenting cell immune therapeutics for gliomas.

  • Authors : Lee-Chang C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Malnati Brain Tumor Institute, Chicago, Illinois, USA.

Subjects: Glioma*/Glioma*/Glioma*/therapy ; Cancer Vaccines*; Humans

  • Source: The Journal of clinical investigation [J Clin Invest] 2023 Feb 01; Vol. 133 (3). Date of Electronic Publication: 2023 Feb 01.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Randomized trial of neoadjuvant vaccination with tumor-cell lysate induces T cell response in low-grade gliomas.

  • Authors : Ogino H; Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA.; Department of Respiratory Medicine & Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.

Subjects: Cancer Vaccines*/Cancer Vaccines*/Cancer Vaccines*/administration & dosage ; Cancer Vaccines*/Cancer Vaccines*/Cancer Vaccines*/immunology ; Glioma*/Glioma*/Glioma*/immunology

  • Source: The Journal of clinical investigation [J Clin Invest] 2022 Feb 01; Vol. 132 (3).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Imaging activated T cells predicts response to cancer vaccines.

  • Authors : Alam IS; Department of Radiology.; Molecular Imaging Program at Stanford.

Subjects: Lymphocyte Activation* ; Positron-Emission Tomography*; Cancer Vaccines/Cancer Vaccines/Cancer Vaccines/*immunology

  • Source: The Journal of clinical investigation [J Clin Invest] 2018 Jun 01; Vol. 128 (6), pp. 2569-2580. Date of Electronic Publication: 2018 May 14.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

A therapeutic cancer vaccine delivers antigens and adjuvants to lymphoid tissues using genetically modified T cells.

  • Authors : Veatch JR; Clinical Research Division and Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center (FHCRC), Seattle, Washington, USA.; Department of Medicine, University of Washington, Seattle, Washington, USA.

Subjects: CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*immunology ; Cancer Vaccines/Cancer Vaccines/Cancer Vaccines/*therapeutic use; Adjuvants, Immunologic/Adjuvants, Immunologic/Adjuvants, Immunologic/administration & dosage

  • Source: The Journal of clinical investigation [J Clin Invest] 2021 Aug 16; Vol. 131 (16).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

An unbiased approach to defining bona fide cancer neoepitopes that elicit immune-mediated cancer rejection.

  • Authors : Brennick CA; Department of Immunology, and Carole and Ray Neag Comprehensive Cancer Center, University of Connecticut School of Medicine, Farmington, Connecticut, USA.; George MM

Subjects: Antigens, Neoplasm*/Antigens, Neoplasm*/Antigens, Neoplasm*/immunology ; Antigens, Neoplasm*/Antigens, Neoplasm*/Antigens, Neoplasm*/pharmacology ; Cancer Vaccines*/Cancer Vaccines*/Cancer Vaccines*/immunology

  • Source: The Journal of clinical investigation [J Clin Invest] 2021 Feb 01; Vol. 131 (3).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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Academic Journal

Vaccines for immunoprevention of cancer.

  • Authors : Enokida T; Department of Medicine, Precision Immunology Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Moreira A

Subjects: Immunotherapy*; Antigens, Neoplasm/Antigens, Neoplasm/Antigens, Neoplasm/*therapeutic use ; Cancer Vaccines/Cancer Vaccines/Cancer Vaccines/*therapeutic use

  • Source: The Journal of clinical investigation [J Clin Invest] 2021 May 03; Vol. 131 (9).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model:

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