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Publisher : american society for clinical investigation Subject : cells Filter by : Subject

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Academic Journal

HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.

Authors : Singhal, Rashi; Mitta, Sreedhar R.; Das, Nupur K.

Subjects: COLORECTAL cancer; CELL death; HYPOXIA-inducible factors

Source: Journal of Clinical Investigation. 6/15/2021, Vol. 131 Issue 12, p1-15. 15p.

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Academic Journal

Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade.

Authors : Sehgal, Kartik; Portell, Andrew; Ivanova, Elena V.

Subjects: PROGRAMMED cell death 1 receptors; NUCLEOTIDE sequence; RNA sequencing

Source: Journal of Clinical Investigation. 1/15/2021, Vol. 131 Issue 2, p1-17. 17p. 1 Chart, 6 Graphs.

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Academic Journal

Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production.

Authors : Reinert, Line S.; Rashidi, Ahmad S.; Tran, Diana N.

Subjects: HUMAN herpesvirus 1; CELL death; APOPTOSIS

Source: Journal of Clinical Investigation. Jan2021, Vol. 131 Issue 1, p1-17. 17p.

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Academic Journal

ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.

Authors : Hirose, Takuo; Cabrera-Socorro, Alfredo; Chitayat, David

Subjects: NEURAL stem cells; CENTRAL nervous system; NEURODEGENERATION

Source: Journal of Clinical Investigation. May2019, Vol. 129 Issue 5, p2145-2162. 18p.

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Academic Journal

Galactose protects against cell damage in mouse models of acute pancreatitis.

Authors : Shuang Peng; Gerasimenko, Julia V.; Tsugorka, Tetyana M.

Subjects: GALACTOSE; PANCREATITIS; ASPARAGINASE

Source: Journal of Clinical Investigation. 8/31/2018, Vol. 128 Issue 9, p3769-3778. 10p.

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Academic Journal

Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.

Authors : Massaad, Michel J.; Jia Zhou; Daisuke Tsuchimoto

Subjects: APOPTOSIS; CELL death; AUTOIMMUNITY

Source: Journal of Clinical Investigation. Nov2016, Vol. 126 Issue 11, p4219-4236. 18p. 2 Diagrams, 2 Charts, 7 Graphs.

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Academic Journal

βCell death and dysfunction during type 1 diabetes development in at-risk individuals.

Authors : Herold, Kevan C.; Usmani-Brown, Sahar; Ghazi, Tara

Subjects: CELL death; CELLS; TYPE 1 diabetes

Source: Journal of Clinical Investigation. Mar2015, Vol. 125 Issue 3, p1163-1173. 11p. 1 Color Photograph, 1 Diagram, 2 Charts, 4 Graphs.

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Academic Journal

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.

Authors : Lam, Hilaire C (AUTHOR); Cloonan, Suzanne M (AUTHOR); Bhashyam, Abhiram R (AUTHOR)

Subjects: ANIMAL experimentation; BIOCHEMISTRY; CELL culture

Source: Journal of Clinical Investigation. Dec2013, Vol. 123 Issue 12, p5212-5230. 19p.

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Academic Journal

Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells.

Authors : Ivanov, Andrei; Beers, Stephen A.; Walshe, Claire A.

Subjects: CELL death; IMMUNOGLOBULINS; CELL adhesion molecules

Source: Journal of Clinical Investigation. Aug2009, Vol. 119 Issue 8, p2143-2159. 17p. 2 Black and White Photographs, 9 Graphs.

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Academic Journal

Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death.

Authors : Diwan, Abhinav; Matkovich, Scot J.; Qunying Yuan

Subjects: ENDOPLASMIC reticulum; MITOCHONDRIA; PROTEINS

Source: Journal of Clinical Investigation. Jan2009, Vol. 119 Issue 1, p203-212. 10p. 4 Color Photographs, 2 Black and White Photographs, 1 Diagram, 6 Graphs.

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