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Academic Journal

PAI-1 deficiency drives pulmonary vascular smooth muscle remodeling and pulmonary hypertension.

  • Authors : Kudryashova TV; University of Pittsburgh Heart, Blood, and Vascular Medicine Institute, Pittsburgh, Pennsylvania, United States.; Zaitsev SV

Subjects: Plasminogen Activator Inhibitor 1*/Plasminogen Activator Inhibitor 1*/Plasminogen Activator Inhibitor 1*/metabolism ; Plasminogen Activator Inhibitor 1*/Plasminogen Activator Inhibitor 1*/Plasminogen Activator Inhibitor 1*/genetics ; Vascular Remodeling*

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2024 Sep 01; Vol. 327 (3), pp. L319-L326. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

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Academic Journal

A comprehensive map of proteoglycan expression and deposition in the pulmonary arterial wall in health and pulmonary hypertension.

  • Authors : Mutgan AC; Division of Physiology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.; Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.

Subjects: Pulmonary Artery*/Pulmonary Artery*/Pulmonary Artery*/metabolism ; Pulmonary Artery*/Pulmonary Artery*/Pulmonary Artery*/pathology ; Proteoglycans*/Proteoglycans*/Proteoglycans*/metabolism

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2024 Aug 01; Vol. 327 (2), pp. L173-L188. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

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Academic Journal

Sodium-glucose cotransporter 1 promotes the biofunctions of perivascular preadipocytes mediated by Akt/mTOR/p70S6K signaling pathway.

  • Authors : Liu Z; Department of Cardiology, The Second Hospital of Shandong University, Jinan, China.; Division of Life Sciences and Medicine, Department of Cardiology, the First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, China.

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism ; TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/genetics

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2024 Jun 01; Vol. 326 (6), pp. C1611-C1624. Date of Electronic Publication: 2024 Apr 22.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model:

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Academic Journal

Pneumonectomy combined with SU5416 or monocrotaline pyrrole does not cause severe pulmonary hypertension in mice.

  • Authors : Sun XQ; Department of Pulmonary Medicine, Amsterdam UMC, VU University Medical Center, Amsterdam Cardiovascular Sciences (ACS), Amsterdam, The Netherlands.; Klouda T

Subjects: Monocrotaline*/Monocrotaline*/Monocrotaline*/analogs & derivatives ; Pyrroles*/Pyrroles*/Pyrroles*/pharmacology ; Hypertension, Pulmonary*/Hypertension, Pulmonary*/Hypertension, Pulmonary*/pathology

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2024 Aug 01; Vol. 327 (2), pp. L250-L257. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

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Academic Journal

Repetitive sulfur dioxide exposure in mice models post-deployment respiratory syndrome.

  • Authors : Gutor SS; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States.; Salinas RI

Subjects: Sulfur Dioxide* ; Disease Models, Animal*; Animals

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2024 May 01; Vol. 326 (5), pp. L539-L550. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

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Academic Journal

Loss of prolyl hydroxylase 1 and 2 in SM22α-expressing cells prevents Hypoxia-Induced pulmonary hypertension.

  • Authors : Barnes EA; Department of Pediatrics, Center for Excellence in Pulmonary Biology, Stanford University, School of Medicine, Stanford, California, United States.; Ito R

Subjects: Hypertension, Pulmonary*/Hypertension, Pulmonary*/Hypertension, Pulmonary*/metabolism ; Pulmonary Arterial Hypertension*/Pulmonary Arterial Hypertension*/Pulmonary Arterial Hypertension*/metabolism; Animals

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2023 Dec 01; Vol. 325 (6), pp. L741-L755. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

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Academic Journal

Overexpression of dimethylarginine dimethylaminohydrolase 1 protects from angiotensin II-induced cardiac hypertrophy and vascular remodeling.

  • Authors : Kopaliani I; Department of Physiology, Medical Faculty, Dresden University of Technology, Dresden, Germany.; Jarzebska N

Subjects: Blood Pressure* ; Vascular Remodeling* ; Ventricular Function, Left*

  • Source: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2021 Nov 01; Vol. 321 (5), pp. H825-H838. Date of Electronic Publication: 2021 Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model:

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Academic Journal

Aloperine protects pulmonary hypertension via triggering PPARγ signaling and inhibiting calcium regulatory pathway in pulmonary arterial smooth muscle cells.

  • Authors : Shan X; Department of Pulmonary and Critical Care Medicine, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Subjects: Calcium Signaling*/Calcium Signaling*/Calcium Signaling*/drug effects ; Hypertension, Pulmonary*/Hypertension, Pulmonary*/Hypertension, Pulmonary*/metabolism ; Hypertension, Pulmonary*/Hypertension, Pulmonary*/Hypertension, Pulmonary*/prevention & control

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2023 Oct 01; Vol. 325 (4), pp. C1058-C1072. Date of Electronic Publication: 2023 Sep 04.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model:

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Academic Journal

Human pulmonary microvascular endothelial cell DDAH1-mediated nitric oxide production promotes pulmonary smooth muscle cell apoptosis in co-culture.

  • Authors : Almazroue H; Pulmonary Hypertension Group, Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States.; Jin Y

Subjects: Hypertension, Pulmonary*/Hypertension, Pulmonary*/Hypertension, Pulmonary*/metabolism ; Bronchopulmonary Dysplasia*; Infant

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2023 Sep 01; Vol. 325 (3), pp. L360-L367. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

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Academic Journal

The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions.

  • Authors : Nakahara M; Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland.; Ito H

Subjects: Vascular Remodeling*; Hypertension, Pulmonary/Hypertension, Pulmonary/Hypertension, Pulmonary/*metabolism ; Hypoxia/Hypoxia/Hypoxia/*metabolism

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Aug 01; Vol. 321 (2), pp. L416-L428. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

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