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Academic Journal

Proteolytic degradation of atrial sarcomere proteins underlies contractile defects in atrial fibrillation.

  • Authors : Cizauskas HE; Department of Cell and Molecular Physiology, Loyola University Chicago, Chicago, Illinois, United States.; Burnham HV

Subjects: Atrial Fibrillation*/Atrial Fibrillation*/Atrial Fibrillation*/metabolism ; Atrial Fibrillation*/Atrial Fibrillation*/Atrial Fibrillation*/physiopathology ; Myocardial Contraction*

  • Source: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2024 Aug 01; Vol. 327 (2), pp. H460-H472. Date of Electronic Publication: 2024 Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model:

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Academic Journal

Influence of proteolytic cleavage of ENaC's γ subunit upon Na + and K + handling.

  • Authors : Ray EC; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.; Nickerson A

Subjects: Epithelial Sodium Channels*/Epithelial Sodium Channels*/Epithelial Sodium Channels*/metabolism ; Epithelial Sodium Channels*/Epithelial Sodium Channels*/Epithelial Sodium Channels*/genetics ; Sodium*/Sodium*/Sodium*/metabolism

  • Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2024 Jun 01; Vol. 326 (6), pp. F1066-F1077. Date of Electronic Publication: 2024 Apr 18.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model:

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Academic Journal

Extracellular BMP1 is the major proteinase for COOH-terminal proteolysis of type I procollagen in lung fibroblasts.

  • Authors : N'Diaye EN; Department of Discovery Immunology, Genentech, South San Francisco, California.; Cook R

Subjects: Proteolysis*/Proteolysis*/Proteolysis*/drug effects; Bone Morphogenetic Protein 1/Bone Morphogenetic Protein 1/Bone Morphogenetic Protein 1/*metabolism ; Extracellular Fluid/Extracellular Fluid/Extracellular Fluid/*metabolism

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2021 Feb 01; Vol. 320 (2), pp. C162-C174. Date of Electronic Publication: 2020 Nov 18.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model:

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Academic Journal

Pharmacokinetics and pharmacodynamics of TTI-101, a STAT3 inhibitor that blocks muscle proteolysis in rats with chronic kidney disease.

  • Authors : Zhang L; Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, Texas.; Wang Y

Subjects: Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Muscle, Skeletal/Muscle, Skeletal/Muscle, Skeletal/*drug effects ; Naphthols/Naphthols/Naphthols/*pharmacology

  • Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 Jul 01; Vol. 319 (1), pp. F84-F92. Date of Electronic Publication: 2020 Jun 01.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model:

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Academic Journal

Myocardial overexpression of TIMP3 after myocardial infarction exerts beneficial effects by promoting angiogenesis and suppressing early proteolysis.

  • Authors : Takawale A; Department of Physiology, University of Alberta, Edmonton, Alberta, Canada.; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada.

Subjects: Neovascularization, Physiologic* ; Proteolysis* ; Ventricular Function, Left*

  • Source: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2017 Aug 01; Vol. 313 (2), pp. H224-H236. Date of Electronic Publication: 2017 Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model:

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Academic Journal

Glycans in the intestinal peptide transporter PEPT1 contribute to function and protect from proteolysis.

Subjects: Protein Processing, Post-Translational* ; Proteolysis*; Dipeptides/Dipeptides/Dipeptides/*metabolism

  • Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2017 Jun 01; Vol. 312 (6), pp. G580-G591. Date of Electronic Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model:

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Academic Journal

The phosphodiesterase-4 inhibitor roflumilast reverts proteolysis in skeletal muscle cells of patients with COPD cachexia.

  • Authors : Barreiro E; Pulmonology Department, Muscle and Respiratory System Research Unit, Hospital del Mar Medical Research Institute, Parc de Salut Mar, and Health and Experimental Sciences Department, Universitat Pompeu Fabra , Barcelona , Spain.; Centro de Investigación en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III , Madrid , Spain.

Subjects: Aminopyridines/Aminopyridines/Aminopyridines/*therapeutic use ; Benzamides/Benzamides/Benzamides/*therapeutic use ; Muscle, Skeletal/Muscle, Skeletal/Muscle, Skeletal/*drug effects

  • Source: Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2018 Aug 01; Vol. 125 (2), pp. 287-303. Date of Electronic Publication: 2018 Apr 12.Publisher: American Physiological Society Country of Publication: United States NLM ID: 8502536 Publication Model:

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Academic Journal

Intestinal serine protease inhibition increases FGF21 and improves metabolism in obese mice.

  • Authors : Albarazanji K; Cardiovascular and Metabolic Disease Discovery, Janssen R&D, LLC, Spring House, Pennsylvania.; Jennis M

Subjects: Fibroblast Growth Factors*/Fibroblast Growth Factors*/Fibroblast Growth Factors*/blood ; Fibroblast Growth Factors*/Fibroblast Growth Factors*/Fibroblast Growth Factors*/metabolism ; Proteolysis*

  • Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2019 May 01; Vol. 316 (5), pp. G653-G667. Date of Electronic Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model:

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Academic Journal

Mechanisms of Niemann-Pick type C1 Like 1 protein degradation in intestinal epithelial cells.

  • Authors : Malhotra P; Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.; Soni V

Subjects: Proteolysis*; Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism ; Intestinal Mucosa/Intestinal Mucosa/Intestinal Mucosa/*metabolism

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2019 Apr 01; Vol. 316 (4), pp. C559-C566. Date of Electronic Publication: 2019 Feb 21.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model:

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Academic Journal

Insulin does not stimulate muscle protein synthesis during increased plasma branched-chain amino acids alone but still decreases whole body proteolysis in humans.

  • Authors : Everman S; Center for Metabolic and Vascular Biology, Arizona State University, Tempe, Arizona.; Meyer C

Subjects: Amino Acids, Branched-Chain/Amino Acids, Branched-Chain/Amino Acids, Branched-Chain/*pharmacology ; Hypoglycemic Agents/Hypoglycemic Agents/Hypoglycemic Agents/*pharmacology ; Insulin/Insulin/Insulin/*pharmacology

  • Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2016 Oct 01; Vol. 311 (4), pp. E671-E677. Date of Electronic Publication: 2016 Aug 16.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model:

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