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Academic Journal

Methylglyoxal reduces molecular responsiveness to 4 weeks of endurance exercise in mouse plantaris muscle.

  • Authors : Egawa T; Laboratory of Health and Exercise Sciences, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan.; Ogawa T

Subjects: Physical Conditioning, Animal*/Physical Conditioning, Animal*/Physical Conditioning, Animal*/physiology ; Pyruvaldehyde*/Pyruvaldehyde*/Pyruvaldehyde*/metabolism ; Pyruvaldehyde*/Pyruvaldehyde*/Pyruvaldehyde*/pharmacology

  • Source: Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2022 Feb 01; Vol. 132 (2), pp. 477-488. Date of Electronic Publication: 2022 Jan 13.Publisher: American Physiological Society Country of Publication: United States NLM ID: 8502536 Publication Model:

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Academic Journal

Anti-C5a complementary peptide mitigates zymosan-induced severe peritonitis with fibrotic encapsulation in rats pretreated with methylglyoxal.

  • Authors : Iguchi D; Nephrology, Nagoya University Graduate School of Medicine , Nagoya , Japan.; Mizuno M

Subjects: Pyruvaldehyde* ; Zymosan*; Complement Activation/Complement Activation/Complement Activation/*drug effects

  • Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2018 Dec 01; Vol. 315 (6), pp. F1732-F1746. Date of Electronic Publication: 2018 Oct 03.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model:

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Academic Journal

Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases.

  • Authors : Schalkwijk CG; CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre, Maastricht, The Netherlands; and Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.

Subjects: Cardiovascular Diseases/Cardiovascular Diseases/Cardiovascular Diseases/*metabolism ; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*metabolism ; Neoplasms/Neoplasms/Neoplasms/*metabolism

  • Source: Physiological reviews [Physiol Rev] 2020 Jan 01; Vol. 100 (1), pp. 407-461. Date of Electronic Publication: 2019 Sep 20.Publisher: American Physiological Society Country of Publication: United States NLM ID: 0231714 Publication Model:

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Academic Journal

Methylglyoxal triggers human aortic endothelial cell dysfunction via modulation of the K ATP /MAPK pathway.

  • Authors : Wang Y; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University , Detroit, Michigan.; Hall LM

Subjects: Neovascularization, Physiologic*/Neovascularization, Physiologic*/Neovascularization, Physiologic*/drug effects; Aorta/Aorta/Aorta/*drug effects ; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*enzymology

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2019 Jul 01; Vol. 317 (1), pp. C68-C81. Date of Electronic Publication: 2019 Apr 17.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model:

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Academic Journal

Methylglyoxal mediates vascular inflammation via JNK and p38 in human endothelial cells.

  • Authors : Yamawaki H; Dept. of Veterinary Pharmacology, Kitasato University., Towada, Aomori 034-8628, Japan. ; Saito K

Subjects: Endothelial Cells/Endothelial Cells/Endothelial Cells/*metabolism ; Endothelial Cells/Endothelial Cells/Endothelial Cells/*pathology ; Inflammation/Inflammation/Inflammation/*metabolism

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2008 Dec; Vol. 295 (6), pp. C1510-7. Date of Electronic Publication: 2008 Oct 08.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model:

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Academic Journal

Accumulation of methylglyoxal increases the advanced glycation end-product levels in DRG and contributes to lumbar disk herniation-induced persistent pain.

  • Authors : Liu CC; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Rehabilitation Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China; and.

Subjects: Ganglia, Spinal/Ganglia, Spinal/Ganglia, Spinal/*metabolism ; Glycation End Products, Advanced/Glycation End Products, Advanced/Glycation End Products, Advanced/*metabolism ; Intervertebral Disc Displacement/Intervertebral Disc Displacement/Intervertebral Disc Displacement/*metabolism

  • Source: Journal of neurophysiology [J Neurophysiol] 2017 Aug 01; Vol. 118 (2), pp. 1321-1328. Date of Electronic Publication: 2017 Jun 14.Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model:

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Academic Journal

The SUR2B subunit of rat vascular KATP channel is targeted by miR-9a-3p induced by prolonged exposure to methylglyoxal.

  • Authors : Li SS; Department of Biology, Georgia State University, Atlanta, Georgia.; Wu Y

Subjects: ATP-Binding Cassette Transporters/ATP-Binding Cassette Transporters/ATP-Binding Cassette Transporters/*metabolism ; KATP Channels/KATP Channels/KATP Channels/*metabolism ; MicroRNAs/MicroRNAs/MicroRNAs/*metabolism

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2015 Jan 15; Vol. 308 (2), pp. C139-45. Date of Electronic Publication: 2014 Oct 29.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model:

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Academic Journal

Effects of methylglyoxal on human cardiac fibroblast: roles of transient receptor potential ankyrin 1 (TRPA1) channels.

  • Authors : Oguri G; Department of Cardiovascular Medicine, University of Tokyo, Tokyo, Japan;

Subjects: Calcium Channels/Calcium Channels/Calcium Channels/*metabolism ; Fibroblasts/Fibroblasts/Fibroblasts/*drug effects ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*metabolism

  • Source: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2014 Nov 01; Vol. 307 (9), pp. H1339-52. Date of Electronic Publication: 2014 AugPublisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model:

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Academic Journal

Prolonged exposure to methylglyoxal causes disruption of vascular KATP channel by mRNA instability.

  • Authors : Yang Y; Deptartment of Biology, Georgia State University, 100 Piedmont Ave., Atlanta, GA 30302, USA.; Li S

Subjects: ATP-Binding Cassette Transporters/ATP-Binding Cassette Transporters/ATP-Binding Cassette Transporters/*metabolism ; KATP Channels/KATP Channels/KATP Channels/*metabolism ; Potassium Channels, Inwardly Rectifying/Potassium Channels, Inwardly Rectifying/Potassium Channels, Inwardly Rectifying/*metabolism

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2012 Nov 15; Vol. 303 (10), pp. C1045-54. Date of Electronic Publication: 2012 Sep 12.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model:

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Academic Journal

Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity.

  • Authors : Wang XL; Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.; Lau WB

Subjects: Glycation End Products, Advanced/Glycation End Products, Advanced/Glycation End Products, Advanced/*metabolism ; Myocardial Reperfusion Injury/Myocardial Reperfusion Injury/Myocardial Reperfusion Injury/*pathology ; Myocytes, Cardiac/Myocytes, Cardiac/Myocytes, Cardiac/*pathology

  • Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2010 Aug; Vol. 299 (2), pp. E207-14. Date of Electronic Publication: 2010 May 11.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model:

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