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Academic Journal

Bone marrow stromal cells enhance differentiation of acute myeloid leukemia induced by pyrimidine synthesis inhibitors.

Authors : Smoljo, Tomislav; Lalic, Hrvoje; Dembitz, Vilma

Subjects: MESENCHYMAL stem cells; CHECKPOINT kinase 1; DIHYDROOROTATE dehydrogenase

Source: American Journal of Physiology: Cell Physiology; Nov2024, Vol. 327 Issue 5, pC1202-C1218, 17p

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Academic Journal

Asparagine as a signal for glutamine sufficiency via asparagine synthetase: a fresh evidence-based framework in physiology and oncology.

Authors : Olawuni, Babatunde; Bode, Barrie P.

Subjects: SECOND messengers (Biochemistry); AMINO acids; ASPARAGINE

Source: American Journal of Physiology: Cell Physiology; Nov2024, Vol. 327 Issue 5, pC1335-C1346, 12p

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Academic Journal

A brief harvesting-freezing delay significantly alters the kidney metabolome and leads to false positive and negative results.

Authors : Alsawaf, Yahya; Maksimovic, Igor; Zheng, Jamie

Subjects: POLYCYSTIC kidney disease; LABORATORY rats; METABOLOMIC fingerprinting

Source: American Journal of Physiology: Renal Physiology; Nov2024, Vol. 327 Issue 5, pF697-F711, 15p

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Academic Journal

Identification of natriuretic peptide receptor A-related gene expression signatures in podocytes in vivo reveals baseline control of protective pathways.

Authors : Jensen, Mia; Heinl, Elena-Sofia; Federlein, Anna

Subjects: ATRIAL natriuretic peptides; BRAIN natriuretic factor; NATRIURETIC peptides

Source: American Journal of Physiology: Renal Physiology; Nov2024, Vol. 327 Issue 5, pF806-F821, 16p

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Academic Journal

Now and then in eukaryotic DNA methylation.

Authors : Stein, Richard A.; Gomaa, Faris E.; Raparla, Pranaya

Subjects: DNA demethylation; DNA methylation; GENE expression

Source: Physiological Genomics; Nov2024, Vol. 56 Issue 11, p741-763, 23p

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Academic Journal

Extrarenal Benefits of SGLT2 Inhibitors in the Treatment of Cardiomyopathies.

Authors : Yerra, Veera Ganesh; Connelly, Kim A.

Subjects: MYOCARDIUM; HYPERTROPHIC cardiomyopathy; DILATED cardiomyopathy

Source: Physiology; Nov2024, Vol. 39 Issue 6, p412-434, 23p

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Academic Journal

Clitocine enhances the drug sensitivity of colon cancer cells by promoting FBXW7-mediated MCL-1 degradation via inhibiting the A2B/cAMP/ERK axis.

Authors : Feng Ruan; Yanyun Ruan; Huamin Gu

Subjects: CYCLIC adenylic acid; COLON cancer; MYELOID cells

Source: American Journal of Physiology: Cell Physiology; Oct2024, Vol. 327 Issue 4, pC884-C900, 17p

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Academic Journal

Tumor microenvironment-like conditions alter pancreatic cancer cell metabolism and behavior.

Authors : Gardner, Georgina Louise; Stuart, Jeffrey Alan

Subjects: CYTOLOGY; CELL metabolism; CELL migration

Source: American Journal of Physiology: Cell Physiology; Oct2024, Vol. 327 Issue 4, pC959-C978, 20p

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Academic Journal

Eukaryotic cell size regulation and its implications for cellular function and dysfunction.

Authors : Chadha, Yagya; Khurana, Arohi; Schmoller, Kurt M.

Subjects: CELL size; CELLULAR control mechanisms; CELL physiology

Source: Physiological Reviews; Oct2024, Vol. 104 Issue 4, p1679-1717, 39p

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Academic Journal

SGLT2 inhibition leads to a restoration of hepatic and circulating metabolites involved in the folate cycle and pyrimidine biosynthesis.

Authors : Mendez Espinoza I; Department of Human Science, Georgetown University, Washington, District of Columbia, United States.; Choos END

Subjects: Sodium-Glucose Transporter 2 Inhibitors*/Sodium-Glucose Transporter 2 Inhibitors*/Sodium-Glucose Transporter 2 Inhibitors*/pharmacology ; Liver*/Liver*/Liver*/metabolism ; Liver*/Liver*/Liver*/drug effects

Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2024 Aug 01; Vol. 327 (2), pp. G235-G253. Date of Electronic Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model:

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