Search Results

In well-differentiated primary human bronchial epithelial cells, TGF- β 1 and TGF- β 2 induce expression of furin.

• Authors : O'Sullivan MJ; Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.; Mitchel JA

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/pathogenicity ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/physiology; Bronchi/Bronchi/Bronchi/*metabolism

• Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Feb 01; Vol. 320 (2), pp. L246-L253. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

Record details

The proprotein convertase furin inhibits IL-13-induced inflammation in airway smooth muscle by regulating integrin-associated signaling complexes.

• Authors : Wu Y; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, Indianapolis, Indiana.; Huang Y

Subjects: Furin/Furin/Furin/*pharmacology ; Inflammation/Inflammation/Inflammation/*prevention & control ; Integrins/Integrins/Integrins/*metabolism

• Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Jul 01; Vol. 321 (1), pp. L102-L115. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

Record details

Differential expression of the pro-natriuretic peptide convertases corin and furin in experimental heart failure and atrial fibrosis.

• Authors : Ichiki T; Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA. ; Boerrigter G

Subjects: Furin/Furin/Furin/*metabolism ; Heart Failure/Heart Failure/Heart Failure/*enzymology ; Heart Ventricles/Heart Ventricles/Heart Ventricles/*enzymology

• Source: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2013 Jan 15; Vol. 304 (2), pp. R102-9. Date of Electronic Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901230 Publication Model:

Record details

Sox9-dependent transcriptional regulation of the proprotein convertase furin.

• Authors : Guimont P; Immunology Division, Faculty of Medicine, Université de Sherbrooke, QC, Canada J1H 5N4.; Grondin F

Subjects: Promoter Regions, Genetic* ; Transcription, Genetic*; Cell Differentiation/Cell Differentiation/Cell Differentiation/*genetics

• Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2007 Jul; Vol. 293 (1), pp. C172-83. Date of Electronic Publication: 2007 Mar 14.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model:

Record details

The CDX2 transcription factor regulates furin expression during intestinal epithelial cell differentiation.

• Authors : Gendron FP; Département d'Anatomie et de Biologie Cellulaire, Faculté de Médecine, Université de Sherbrooke, Sherbrooke, QC, Canada J1H5N4.; Mongrain S

Subjects: Cell Differentiation/Cell Differentiation/Cell Differentiation/*genetics ; Cell Differentiation/Cell Differentiation/Cell Differentiation/*physiology ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*physiology

• Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2006 Feb; Vol. 290 (2), pp. G310-8. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model:

Record details

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

• Authors : Sheng S; Dept. of Medicine, Univ. of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.; Carattino MD

Subjects: Furin/Furin/Furin/*metabolism ; Sodium/Sodium/Sodium/*pharmacology ; Sodium Channel Blockers/Sodium Channel Blockers/Sodium Channel Blockers/*pharmacology

• Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2006 Jun; Vol. 290 (6), pp. F1488-96. Date of Electronic Publication: 2006 Jan 31.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model:

Record details

Proprotein convertases play an important role in regulating PKGI endoproteolytic cleavage and nuclear transport.

• Authors : Kato S; Cardiovascular Research Center of the General Medical Services, Massachusetts General Hospital, Boston, MA, USA.; Zhang R

Subjects: Proteolysis*; Cell Nucleus/Cell Nucleus/Cell Nucleus/*enzymology ; Cyclic GMP-Dependent Protein Kinase Type I/Cyclic GMP-Dependent Protein Kinase Type I/Cyclic GMP-Dependent Protein Kinase Type I/*metabolism

• Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2013 Jul 15; Vol. 305 (2), pp. L130-40. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model:

Record details

In well-differentiated primary human bronchial epithelial cells, TGF-b1 and TGF-b2 induce expression of furin.

• Source: American Journal of Physiology: Lung Cellular & Molecular Physiology; Feb2021, Vol. 320 Issue 2, p246-253, 8p, 1 Color Photograph, 1 Chart, 3 Graphs

Record details

Covid-19 infection and mortality: a physiologist's perspective enlightening clinical features and plausible interventional strategies.

• Authors : Abassi, Zaid A.; Skorecki, Karl; Heyman, Samuel Noam

Subjects: COVID-19; SARS virus; SARS-CoV-2

• Source: American Journal of Physiology: Lung Cellular & Molecular Physiology; May2020, Vol. 318 Issue 5, pL1020-L1022, 3p

Record details

Kex2 family endoprotease furin is expressed specifically in pit-region parietal cells of the rat...

• Authors : Kamimura, Hitoshi; Konda, Yoshitaka

Subjects: TRANSFORMING growth factors; GASTRIC mucosa; PROTEOLYTIC enzymes

• Source: American Journal of Physiology: Gastrointestinal & Liver Physiology; Jul1999, Vol. 277 Issue 1, pG183, 8p, 5 Color Photographs, 1 Graph

Record details