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Shared Clavulanate and Tazobactam Antigenic Determinants Activate T‑Cells from Hypersensitive Patients.

• Authors : Ariza, Adriana; Jaruthamsophon, Kanoot; Meng, Xiaoli

• Source: Chemical Research in Toxicology; 11/21/2022, Vol. 35 Issue 11, p2122-2132, 11p

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Precise Preparation of a High-Purity Key Intermediate of Tazobactam.

• Authors : Zhou, Yanan; Wu, Chengjun; Ma, Hongzhi

• Source: Organic Process Research & Development; 12/18/2020, Vol. 24 Issue 12, p2898-2905, 8p

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Self-Assembled Polymeric Pyridine Copper Catalysts for Huisgen Cycloaddition with Alkynes and Acetylene Gas: Application in Synthesis of Tazobactam.

• Authors : Hu, Hao; Ohno, Aya; Sato, Takuma

• Source: Organic Process Research & Development; Apr2019, Vol. 23 Issue 4, p493-498, 6p

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Why Clinically Used Tazobactam and Sulbactam Are Poor Inhibitors of OXA-10 β-Lactamase: Raman Crystallographic Evidence.

• Authors : Totir, Monica A.; Jooyoung Cha; Ishiwata, Akihiro

• Source: Biochemistry; Apr2008, Vol. 47 Issue 13, p4094-4101, 8p, 1 Diagram, 1 Chart, 6 Graphs

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Inhibitor-Resistant Class A β-Lactamases: Consequences of the Serl30-to-Gly Mutation Seen in Apo and Tazobactam Structures of the SHY-i Variant.

• Authors : Sun, Tao; Bethel, Christopher R.; Bonomo, Robert A.

• Source: Biochemistry; 11/9/2004, Vol. 43 Issue 44, p14111-14117, 7p

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Tazobactam Forms a Stoichiometric trans-Enamine Intermediate in the E166A Variant of SHV-1 β-Lactamase: 1.63 Å Crystal Structure.

• Authors : Padayatti, Pius S.; Helfand, Marion S.; Totir, Monica A.

• Source: Biochemistry; 2/3/2004, Vol. 43 Issue 4, p843-848, 6p

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Different Intermediate Populations Formed by Tazobactam, Sulbactam, and Clavulanate Reacting with SHV-1 β-Lactamases: Raman Crystallographic Evidence.

• Authors : Kalp, Matthew¹; Totir, Monica A.¹; Buynak, John D.²

Subjects: *BETA lactamases; *TAZOBACTAM; *CLAVULANIC acid

• Source: Journal of the American Chemical Society. 2/18/2009, Vol. 131 Issue 6, p2338-2347. 10p. 1 Chart, 1 Graph.

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Inhibition of the SHV-1 beta-Lactamase by Sulfones: Crystallographic Observation of Two Reaction...

• Authors : Kuzin, Alexandre P.; Nukaga, Michiyoshi; Nukaga, Yasuko

Subjects: *BETA lactamases; *TAZOBACTAM

• Source: Biochemistry. 02/13/2001, Vol. 40 Issue 6, p1861. 6p. 4 Diagrams, 3 Charts.

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CUBIST SEEKS CALIXA IN ANTIBIOTIC PUSH.

• Authors : M. M.

Subjects: PHARMACEUTICAL industry mergers; CALIXA Therapeutics Inc.; CUBIST Pharmaceuticals Inc.

• Source: Chemical & Engineering News. 12/21/2009, Vol. 87 Issue 51, p23-23. 1/9p.

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Raman Spectra of Interchanging β-Lactamase Inhibitor Intermediates on the Millisecond Time Scale.

• Authors : Torkabadi, Hossein Heidari¹; Tao Che²; Shou, Jingjing²

Subjects: *BETA-lactamase inhibitors; *INTERMEDIATES (Chemistry); *RAMAN microscopy

• Source: Journal of the American Chemical Society. 2/27/2013, Vol. 135 Issue 8, p2895-2898. 4p.

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