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Academic Journal

Tumor-Targeted Delivery of IL-2 by Fusing with a pH Low Insertion Peptide for Antitumor Immunotherapy.

  • Authors : Chu T; College of Pharmaceutical Science, Jilin University, Changchun 130021, China.; CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.

Subjects: Interleukin-2*/Interleukin-2*/Interleukin-2*/administration & dosage ; Melanoma*/Melanoma*/Melanoma*/drug therapy; Humans

  • Source: Bioconjugate chemistry [Bioconjug Chem] 2023 Oct 18; Vol. 34 (10), pp. 1894-1901. Date of Electronic Publication: 2023 Oct 03.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic

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Academic Journal

Enhanced Local Delivery of Engineered IL-2 mRNA by Porous Silica Nanoparticles to Promote Effective Antitumor Immunity.

  • Authors : Shin H; Department of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.; Kang S

Subjects: Interleukin-2*/Interleukin-2*/Interleukin-2*/genetics ; Nanoparticles*; Animals

  • Source: ACS nano [ACS Nano] 2023 Sep 12; Vol. 17 (17), pp. 17554-17567. Date of Electronic Publication: 2023 Aug 29.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic

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Academic Journal

New Tool for Rapid and Accurate Detection of Interleukin-2 and Soluble Interleukin-2 Receptor α in Cancer Diagnosis Using a Bioresponsive Microgel and Multivalent Protein Binding.

  • Authors : Yang HM; School of Chemical and Biological Engineering, and Institute of Chemical Process, Seoul National University, Seoul 08826, Republic of Korea.; Yim B

Subjects: Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*blood ; Interleukin-2/Interleukin-2/Interleukin-2/*blood ; Interleukin-2 Receptor alpha Subunit/Interleukin-2 Receptor alpha Subunit/Interleukin-2 Receptor alpha Subunit/*blood

  • Source: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Jul 28; Vol. 13 (29), pp. 33782-33789. Date of Electronic Publication: 2021 Jul 14.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic

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Academic Journal

Targeted Association and Intracellular Delivery of Nanocargoes into Primary T Lymphocytes via Interleukin-2 Receptor-Mediated Endocytosis.

  • Authors : Ayyadevara VSSA; Department of Biotechnology Science and Engineering, University of Alabama in Huntsville, Huntsville, Alabama 35899, United States.; Ahmadi A

Subjects: Nanotechnology*; Interleukin-2/Interleukin-2/Interleukin-2/*chemistry ; T-Lymphocytes/T-Lymphocytes/T-Lymphocytes/*metabolism

  • Source: Bioconjugate chemistry [Bioconjug Chem] 2021 Aug 18; Vol. 32 (8), pp. 1675-1687. Date of Electronic Publication: 2021 Jul 09.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic

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Academic Journal

Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity.

  • Authors : Zhou D; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School, Peking University, Shenzhen 518055, China.; Zuo Y

Subjects: Interleukin-2*/Interleukin-2*/Interleukin-2*/metabolism ; Proteomics*; Animals

  • Source: Journal of medicinal chemistry [J Med Chem] 2023 Apr 13; Vol. 66 (7), pp. 4979-4998. Date of Electronic Publication: 2023 Mar 23.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic

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Academic Journal

Site-Selective Tyrosine Phosphorylation in the Activation of the p50 Subunit of NF-κB for DNA Binding and Transcription.

  • Authors : Chen S; Biodesign Center for BioEnergetics, and School of Molecular Sciences, Arizona State University, Tempe, Arizona 85287, United States.; Ji X

Subjects: NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; Interleukin-2*/Interleukin-2*/Interleukin-2*/metabolism; Humans

  • Source: ACS chemical biology [ACS Chem Biol] 2023 Jan 20; Vol. 18 (1), pp. 59-69. Date of Electronic Publication: 2022 Dec 19.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic

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Academic Journal

Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries.

Subjects: DNA/DNA/DNA/*metabolism ; Interleukin-2/Interleukin-2/Interleukin-2/*metabolism; Humans

  • Source: Journal of medicinal chemistry [J Med Chem] 2021 Dec 09; Vol. 64 (23), pp. 17496-17510. Date of Electronic Publication: 2021 Nov 25.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic

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Academic Journal

Differential Effects of IL2Rα and IL15Rα over the Stability of the Common Beta-Gamma Signaling Subunits of the IL2 and IL15 Receptors.

  • Authors : Ponce LF; Molecular System Biology Department, Center of Molecular Immunology, Havana, Havana 11600, Cuba.; Center for Molecular Simulations, Biological Science Department, University of Calgary, Calgary, Alberta, Canada T2N 1N4.

Subjects: Interleukin-15 Receptor alpha Subunit* ; Interleukin-2*; Interleukin Receptor Common gamma Subunit/Interleukin Receptor Common gamma Subunit/Interleukin Receptor Common gamma Subunit/genetics

  • Source: Journal of chemical information and modeling [J Chem Inf Model] 2021 Apr 26; Vol. 61 (4), pp. 1913-1920. Date of Electronic Publication: 2021 Mar 25.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic

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Academic Journal

Enhancing the Pharmacokinetic Profile of Interleukin 2 through Site-Specific Conjugation to a Selective Small-Molecule Transthyretin Ligand.

  • Authors : Liu F; Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, California 95211, United States.; Ul Amin T

Subjects: Interleukin-2/Interleukin-2/Interleukin-2/*pharmacokinetics ; Prealbumin/Prealbumin/Prealbumin/*metabolism ; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/*metabolism

  • Source: Journal of medicinal chemistry [J Med Chem] 2021 Oct 14; Vol. 64 (19), pp. 14876-14886. Date of Electronic Publication: 2021 Sep 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic

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Academic Journal

Long-Acting Human Interleukin 2 Bioconjugate Modified with Fatty Acids by Sortase A.

  • Authors : Qian M; Department of Microbiological & Biochemical Pharmacy, School of Pharmacy, Fudan University, 201203 Shanghai, China.; State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, 201203 Shanghai, China.

Subjects: Aminoacyltransferases/Aminoacyltransferases/Aminoacyltransferases/*chemistry ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*chemistry ; Cysteine Endopeptidases/Cysteine Endopeptidases/Cysteine Endopeptidases/*chemistry

  • Source: Bioconjugate chemistry [Bioconjug Chem] 2021 Mar 17; Vol. 32 (3), pp. 615-625. Date of Electronic Publication: 2021 Mar 03.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic

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  • 1-10 of  236 results for ""INTERLEUKIN-2""