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Academic Journal

Sequential Unfolding Mechanisms of Monomeric Caspases.

  • Authors : Joglekar I; Department of Biology, University of Texas at Arlington, Arlington, Texas 76019, United States.; Clark AC

Subjects: Protein Folding* ; Caspases*; Humans

  • Source: Biochemistry [Biochemistry] 2023 Jun 20; Vol. 62 (12), pp. 1878-1889. Date of Electronic Publication: 2023 May 31.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic

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Academic Journal

Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5- d ]pyrimidin-7(6 H )-one" Scaffold for the Treatment of B Cell Lymphoma.

  • Authors : Liang X; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.; University of Chinese Academy of Sciences, Beijing 100049, China.

Subjects: Caspases*/Caspases*/Caspases*/metabolism ; Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/drug therapy; Humans

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 Feb 22; Vol. 67 (4), pp. 2884-2906. Date of Electronic Publication: 2024 Feb 13.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic

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Academic Journal

Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6.

  • Authors : Van Horn KS; Department of Pharmaceutical Chemistry, University of California, San Francisco, 600 16th Street, San Francisco, California 94143, United States.; Wang D

Subjects: Cysteine* ; Caspases*; Humans

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2023 May 10; Vol. 145 (18), pp. 10015-10021. Date of Electronic Publication: 2023 Apr 27.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic

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Academic Journal

CaspSites: A Database and Web Application for Experimentally Observed Human Caspase Substrates Using N-Terminomics.

  • Authors : Wang H; Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G2H7, Canada.; Julien O

Subjects: Caspases*/Caspases*/Caspases*/chemistry ; Caspases*/Caspases*/Caspases*/metabolism ; Databases, Factual*

  • Source: Journal of proteome research [J Proteome Res] 2023 Feb 03; Vol. 22 (2), pp. 454-461. Date of Electronic Publication: 2023 Jan 25.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic

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Academic Journal

Reactive Oxygen Species and p53 Mediated Activation of p38 and Caspases is Critically Involved in Kaempferol Induced Apoptosis in Colorectal Cancer Cells.

  • Authors : Choi JB; College of Korean Medicine , Kyung Hee University , Seoul 02447 , Korea.; Kim JH

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Caspases/Caspases/Caspases/*metabolism ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*physiopathology

  • Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2018 Sep 26; Vol. 66 (38), pp. 9960-9967. Date of Electronic Publication: 2018 Sep 13.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic

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Academic Journal

The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.

  • Authors : Chuh KN; Department of Chemistry and §Department of Molecular and Computational Biology, University of Southern California , Los Angeles, California 90089-0744, United States.; Batt AR

Subjects: Apoptosis*; Acetylglucosamine/Acetylglucosamine/Acetylglucosamine/*metabolism ; Caspases/Caspases/Caspases/*metabolism

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2017 Jun 14; Vol. 139 (23), pp. 7872-7885. Date of Electronic Publication: 2017 May 31.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic

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Academic Journal

Efficient In Silico Saturation Mutagenesis of a Member of the Caspase Protease Family.

  • Authors : Öhlknecht C; Institute of Molecular Modeling and Simulation, University of Natural Resources and Life Sciences, Vienna A-1190, Austria.; Austrian Centre of Industrial Biotechnology, Petersgasse 14, Graz 8041, Austria.

Subjects: Caspases* ; Peptide Hydrolases*; Computer Simulation

  • Source: Journal of chemical information and modeling [J Chem Inf Model] 2021 Mar 22; Vol. 61 (3), pp. 1193-1203. Date of Electronic Publication: 2021 Feb 11.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic

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Academic Journal

Small Molecule Active Site Directed Tools for Studying Human Caspases.

  • Authors : Poreba M; Department of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology , Wyb. Wyspianskiego 27, 50-370 Wroclaw, Poland.; Szalek A

Subjects: Caspase Inhibitors/Caspase Inhibitors/Caspase Inhibitors/*pharmacology ; Caspases/Caspases/Caspases/*metabolism ; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/*pharmacology

  • Source: Chemical reviews [Chem Rev] 2015 Nov 25; Vol. 115 (22), pp. 12546-629. Date of Electronic Publication: 2015 Nov 09.Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985134R Publication Model: Print-Electronic

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Academic Journal

Development of Activity-Based Reporter Gene Technology for Imaging of Protease Activity with an Exquisite Specificity in a Single Live Cell.

Subjects: Genes, Reporter*; Caspases/Caspases/Caspases/*analysis ; Single-Cell Analysis/Single-Cell Analysis/Single-Cell Analysis/*methods

  • Source: ACS chemical biology [ACS Chem Biol] 2019 Oct 18; Vol. 14 (10), pp. 2276-2285. Date of Electronic Publication: 2019 Sep 25.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic

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Academic Journal

Bimodal Fluorescence-Magnetic Resonance Contrast Agent for Apoptosis Imaging.

  • Authors : Li H; Departments of Chemistry, Molecular Biosciences, Neurobiology, and Radiology , Northwestern University , Evanston , Illinois 60208 , United States.; Parigi G

Subjects: Apoptosis* ; Fluorescence* ; Magnetic Resonance Imaging*

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2019 Apr 17; Vol. 141 (15), pp. 6224-6233. Date of Electronic Publication: 2019 Apr 04.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic

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  • 1-10 of  520 results for ""CASPASES""