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Diverse Synthesis of C-Glycosides by Stereoselective Ni-Catalyzed Carboboration of Glycals.

• Authors : Lyu, Mao-Yun; Jacobo, Samuel A.; Brown, M. Kevin

• Source: Journal of the American Chemical Society; 7/17/2024, Vol. 146 Issue 28, p18866-18872, 7p

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Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M 4 Muscarinic Acetylcholine Receptor.

• Authors : Butler CR; Medicine Design, Medicinal Chemistry, Pfizer Inc., Cambridge, Massachusetts 02139, United States.; Popiolek M

Subjects: Receptor, Muscarinic M4*/Receptor, Muscarinic M4*/Receptor, Muscarinic M4*/metabolism ; Receptor, Muscarinic M4*/Receptor, Muscarinic M4*/Receptor, Muscarinic M4*/agonists ; Drug Design*

• Source: Journal of medicinal chemistry [J Med Chem] 2024 Jul 11; Vol. 67 (13), pp. 10831-10847. Date of Electronic Publication: 2024 Jun 18.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic

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Photochemical Reduction of Quinolines with γ‑Terpinene.

• Authors : Adak, Souvik; Braley, Sarah E.; Brown, M. Kevin

• Source: Organic Letters; 1/12/2024, Vol. 26 Issue 1, p401-405, 5p

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Ni-Catalyzed 1,1- and 1,3-Aminoboration of Unactivated Alkenes.

• Authors : Lyu, Mao-Yun; Morais, Gabriel N.; Chen, Shuming

• Source: Journal of the American Chemical Society; 12/20/2023, Vol. 145 Issue 50, p27254-27261, 8p

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Lewis Acid-Promoted [2 + 2] Cycloadditions of Allenes and Ketenes: Versatile Methods for Natural Product Synthesis.

• Authors : Guo, Renyu; Brown, M. Kevin

• Source: Accounts of Chemical Research; 8/15/2023, Vol. 56 Issue 16, p2253-2264, 12p

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Decreased Transition-State Analogue Affinity in Isotopically Heavy MTAN with Increased Catalysis.

• Authors : Brown M; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States.; Schramm VL

Subjects: Deoxyadenosines*/Deoxyadenosines*/Deoxyadenosines*/chemistry ; Thionucleosides*/Thionucleosides*/Thionucleosides*/chemistry; Catalysis

• Source: Biochemistry [Biochemistry] 2023 Oct 17; Vol. 62 (20), pp. 2928-2933. Date of Electronic Publication: 2023 Oct 03.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic

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Single-Source Precursors for the Controlled Aqueous Synthesis of Bismuth Oxyhalides.

• Authors : Gordon, Matthew N.; Liu, Yanyao; Brown, M. Kevin

• Source: Inorganic Chemistry; 6/19/2023, Vol. 62 Issue 24, p9640-9648, 9p

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Residence Times for Femtomolar and Picomolar Inhibitors of MTANs.

• Authors : Brown M; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States.; Tyler PC

Subjects: Enzyme Inhibitors*/Enzyme Inhibitors*/Enzyme Inhibitors*/chemistry ; Escherichia coli Proteins*/Escherichia coli Proteins*/Escherichia coli Proteins*/chemistry; Escherichia coli/Escherichia coli/Escherichia coli/metabolism

• Source: Biochemistry [Biochemistry] 2023 Jun 06; Vol. 62 (11), pp. 1776-1785. Date of Electronic Publication: 2023 May 19.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic

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Boronic Ester Enabled [2 + 2]-Cycloadditions by Temporary Coordination: Synthesis of Artochamin J and Piperarborenine B.

• Authors : Liu, Yanyao; Ni, Dongshun; Brown, M. Kevin

• Source: Journal of the American Chemical Society; 10/19/2022, Vol. 144 Issue 41, p18790-18796, 7p

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Photochemical Dearomative Cycloadditions of Quinolines and Alkenes: Scope and Mechanism Studies.

• Authors : Guo, Renyu; Adak, Souvik; Bellotti, Peter

• Source: Journal of the American Chemical Society; 9/28/2022, Vol. 144 Issue 38, p17680-17691, 12p

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