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A perspective for biowaivers of human bioequivalence studies on the basis of the combination of the ratio of AUC to the dose and the biopharmaceutics classification system.

• Authors : Sakuma S; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaokatoge-cho, Hirakata, Osaka 573-0101, Japan. ; Tachiki H

Subjects: Area Under Curve* ; Therapeutic Equivalency*; Biopharmaceutics/Biopharmaceutics/Biopharmaceutics/*methods

• Source: Molecular pharmaceutics [Mol Pharm] 2011 Aug 01; Vol. 8 (4), pp. 1113-9. Date of Electronic Publication: 2011 Jun 17.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic

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Using Data-Driven Algorithms with Large-Scale Plasma Proteomic Data to Discover Novel Biomarkers for Diagnosing Depression.

• Authors : Ma S; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan 430060, China.; Li R

Subjects: Biomarkers*/Biomarkers*/Biomarkers*/blood ; Proteomics*/Proteomics*/Proteomics*/methods ; Depression*/Depression*/Depression*/blood

• Source: Journal of proteome research [J Proteome Res] 2024 Sep 06; Vol. 23 (9), pp. 4043-4054. Date of Electronic Publication: 2024 Aug 16.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic

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Application of Mechanistic Multiparameter Optimization and Large-Scale In Vitro to In Vivo Pharmacokinetics Correlations to Small-Molecule Therapeutic Projects.

• Authors : Broccatelli F; Bristol-Myers Squibb Company, San Diego, California 92121, United States.; Veeravalli V

Subjects: Drug Discovery*/Drug Discovery*/Drug Discovery*/methods; Humans ; Machine Learning

• Source: Molecular pharmaceutics [Mol Pharm] 2024 Sep 02; Vol. 21 (9), pp. 4312-4323. Date of Electronic Publication: 2024 Aug 12.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic

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HOPEXGB: A Consensual Model for Predicting miRNA/lncRNA-Disease Associations Using a Heterogeneous Disease-miRNA-lncRNA Information Network.

• Authors : He J; College of Chemistry, Sichuan University, Chengdu 610064, China.; Li M

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; RNA, Long Noncoding*/RNA, Long Noncoding*/RNA, Long Noncoding*/genetics

• Source: Journal of chemical information and modeling [J Chem Inf Model] 2024 Apr 08; Vol. 64 (7), pp. 2863-2877. Date of Electronic Publication: 2023 Aug 21.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic

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FCMSTrans: Accurate Prediction of Disease-Associated nsSNPs by Utilizing Multiscale Convolution and Deep Feature Combination within a Transformer Framework.

• Authors : Zhang M; School of Computer, Jiangsu University of Science and Technology, 666 Changhui Road, Zhenjiang 212100, China.; Gong C

Subjects: Drug Discovery* ; Electric Power Supplies*; Amino Acid Sequence

• Source: Journal of chemical information and modeling [J Chem Inf Model] 2024 Feb 26; Vol. 64 (4), pp. 1394-1406. Date of Electronic Publication: 2024 Feb 13.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic

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Applied Science & Technology Full Text (H.W. Wilson)

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Applied Science & Technology Full Text (H.W. Wilson)

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Simplified Rapid Enrichment of CTCs and Selective Recognition Prereduction Enable a Homogeneous ICP-MS Liquid Biopsy Strategy of Lung Cancer.

• Authors : Wang Y; Department of Laboratory Medicine, Med+X Center for Manufacturing, Department of Thoracic Surgery, Department of Respiratory and Critical Care Medicine, Targeted Tracer Research and Development Laboratory, and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; Chen X

Subjects: Mucin-1* ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/diagnosis; Humans

• Source: Analytical chemistry [Anal Chem] 2023 Sep 26; Vol. 95 (38), pp. 14244-14252. Date of Electronic Publication: 2023 Sep 13.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic

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NeuroPpred-SVM: A New Model for Predicting Neuropeptides Based on Embeddings of BERT.

• Authors : Liu Y; School of Sciences, Anhui Agricultural University, Hefei, Anhui 230036, China.; Wang S

Subjects: Support Vector Machine* ; Neuropeptides*; Algorithms

• Source: Journal of proteome research [J Proteome Res] 2023 Mar 03; Vol. 22 (3), pp. 718-728. Date of Electronic Publication: 2023 Feb 07.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic

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Predictive Models for Human Cytochrome P450 3A7 Selective Inhibitors and Substrates.

• Authors : Xu T; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, Maryland 20850, United States.; Kabir M

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism; Infant, Newborn ; Adult

• Source: Journal of chemical information and modeling [J Chem Inf Model] 2023 Feb 13; Vol. 63 (3), pp. 846-855. Date of Electronic Publication: 2023 Jan 31.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic

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