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Academic Journal

Identification of Potential Aldose Reductase Inhibitors Using Convolutional Neural Network-Based in Silico Screening.

  • Authors : Kashyap K; Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

Subjects: Aldehyde Reductase*/Aldehyde Reductase*/Aldehyde Reductase*/chemistry ; Aldehyde Reductase*/Aldehyde Reductase*/Aldehyde Reductase*/metabolism ; Diabetes Complications*

  • Source: Journal of chemical information and modeling [J Chem Inf Model] 2023 Oct 23; Vol. 63 (20), pp. 6261-6282. Date of Electronic Publication: 2023 Oct 03.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic

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Academic Journal

Novel Hydroxychalcone-Based Dual Inhibitors of Aldose Reductase and α-Glucosidase as Potential Therapeutic Agents against Diabetes Mellitus and Its Complications.

  • Authors : Zhang X; Key Laboratory of Cluster Science, Ministry of Education of China, Beijing Key Laboratory of Photoelectronic; Electrophotonic Conversion Materials, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, China.

Subjects: Aldehyde Reductase* ; Diabetes Mellitus, Experimental*/Diabetes Mellitus, Experimental*/Diabetes Mellitus, Experimental*/chemically induced ; Diabetes Mellitus, Experimental*/Diabetes Mellitus, Experimental*/Diabetes Mellitus, Experimental*/drug therapy

  • Source: Journal of medicinal chemistry [J Med Chem] 2022 Jul 14; Vol. 65 (13), pp. 9174-9192. Date of Electronic Publication: 2022 Jun 24.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic

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Academic Journal

Aldose Reductase Inhibitor Engeletin Suppresses Pelvic Inflammatory Disease by Blocking the Phospholipase C/Protein Kinase C-Dependent/NF-κB and MAPK Cascades.

  • Authors : Wang C; Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; La L

Subjects: Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/*antagonists & inhibitors ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*administration & dosage ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*administration & dosage

  • Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2020 Oct 21; Vol. 68 (42), pp. 11747-11757. Date of Electronic Publication: 2020 Oct 13.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic

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Academic Journal

Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity.

  • Authors : Hlaváč M; Department of Organic Chemistry, Faculty of Natural Sciences , Comenius University in Bratislava , Ilkovičova 6 , 842 15 Bratislava , Slovakia.; Kováčiková L

Subjects: Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/*antagonists & inhibitors ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Indoleacetic Acids/Indoleacetic Acids/Indoleacetic Acids/*pharmacology

  • Source: Journal of medicinal chemistry [J Med Chem] 2020 Jan 09; Vol. 63 (1), pp. 369-381. Date of Electronic Publication: 2019 Dec 30.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic

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Academic Journal

Enhancement of α,ω-Dicarboxylic Acid Production by the Expression of Xylose Reductase for Refactoring Redox Cofactor Regeneration.

  • Authors : Sathesh-Prabu C; School of Energy and Chemical Engineering , Ulsan National Institute of Science and Technology (UNIST) , Ulsan 44919 , Republic of Korea.; Lee SK

Subjects: Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/*genetics ; Dicarboxylic Acids/Dicarboxylic Acids/Dicarboxylic Acids/*metabolism ; Escherichia coli/Escherichia coli/Escherichia coli/*metabolism

  • Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2018 Apr 04; Vol. 66 (13), pp. 3489-3497. Date of Electronic Publication: 2018 Mar 21.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic

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Academic Journal

The C-terminal loop of aldehyde reductase determines the substrate and inhibitor specificity.

  • Authors : Barski OA; Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.; Gabbay KH

Subjects: Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/*chemistry; Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/antagonists & inhibitors ; Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/metabolism

  • Source: Biochemistry [Biochemistry] 1996 Nov 12; Vol. 35 (45), pp. 14276-80.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited

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Academic Journal

Mechanism of human aldehyde reductase: characterization of the active site pocket.

  • Authors : Barski OA; Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.; Gabbay KH

Subjects: Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/*chemistry; Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/antagonists & inhibitors ; Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/genetics

  • Source: Biochemistry [Biochemistry] 1995 Sep 05; Vol. 34 (35), pp. 11264-75.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited

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Academic Journal

Enzymatic Synthesis of a Novel Kaempferol-3-O-β-d-glucopyranosyl-(1→4)-O-α-d-glucopyranoside Using Cyclodextrin Glucanotransferase and Its Inhibitory Effects on Aldose Reductase, Inflammation, and Oxidative Stress.

  • Authors : Choung WJ; Department of Food Science and Nutrition, Hallym University , 1 Hallymdaehak-gil, Chuncheon, Gwangwon-do 24252, South Korea.; Center for Aging and Health Care, Hallym University , 1 Hallymdaehak-gil, Chuncheon, Gwangwon-do 24252, South Korea.

Subjects: Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/*antagonists & inhibitors ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*chemistry ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*chemistry

  • Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2017 Apr 05; Vol. 65 (13), pp. 2760-2767. Date of Electronic Publication: 2017 Mar 24.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic

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Academic Journal

Aldo-Keto Reductase Regulation by the Nrf2 System: Implications for Stress Response, Chemotherapy Drug Resistance, and Carcinogenesis.

  • Authors : Penning TM; Center of Excellence in Environmental Toxicology, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania , Philadelphia, Pennsylvania 19104, United States.

Subjects: Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/*metabolism ; Kelch-Like ECH-Associated Protein 1/Kelch-Like ECH-Associated Protein 1/Kelch-Like ECH-Associated Protein 1/*metabolism ; NF-E2-Related Factor 2/NF-E2-Related Factor 2/NF-E2-Related Factor 2/*metabolism

  • Source: Chemical research in toxicology [Chem Res Toxicol] 2017 Jan 17; Vol. 30 (1), pp. 162-176. Date of Electronic Publication: 2016 Nov 16.Publisher: American Chemical Society Country of Publication: United States NLM ID: 8807448 Publication Model: Print-Electronic

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Academic Journal

Quantification of urinary aflatoxin B1 dialdehyde metabolites formed by aflatoxin aldehyde reductase using isotope dilution tandem mass spectrometry.

  • Authors : Johnson DN; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA.; Egner PA

Subjects: Aflatoxin B1/Aflatoxin B1/Aflatoxin B1/*urine ; Aldehyde Reductase/Aldehyde Reductase/Aldehyde Reductase/*metabolism ; Aldehydes/Aldehydes/Aldehydes/*metabolism

  • Source: Chemical research in toxicology [Chem Res Toxicol] 2008 Mar; Vol. 21 (3), pp. 752-60. Date of Electronic Publication: 2008 Feb 12.Publisher: American Chemical Society Country of Publication: United States NLM ID: 8807448 Publication Model: Print-Electronic

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  • 1-10 of  656 results for ""Aldehyde Reductase""