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Pharmacological Characterization and Investigation of N-Terminal Loop Amino Acids of Adrenomedullin 2 That Are Important for Receptor Activation.

• Authors : Musa H; School of Biological Sciences , The University of Auckland , 3A Symonds Street , Auckland 1010 , New Zealand.; Hendrikse ER

Subjects: Adrenomedullin/Adrenomedullin/Adrenomedullin/*chemistry ; Adrenomedullin/Adrenomedullin/Adrenomedullin/*metabolism ; Receptors, Cell Surface/Receptors, Cell Surface/Receptors, Cell Surface/*metabolism

• Source: Biochemistry [Biochemistry] 2019 Aug 13; Vol. 58 (32), pp. 3468-3474. Date of Electronic Publication: 2019 Jul 29.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic

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Adrenomedullin 2.0: Adjusting Key Levers for Metabolic Stability.

• Authors : Schönauer R; Institut für Biochemie, Universität Leipzig , Brüderstraße 34, 04103 Leipzig, Germany.; Els-Heindl S

Subjects: Adrenomedullin/Adrenomedullin/Adrenomedullin/*metabolism; Adrenomedullin/Adrenomedullin/Adrenomedullin/blood ; Adrenomedullin/Adrenomedullin/Adrenomedullin/chemistry

• Source: Journal of medicinal chemistry [J Med Chem] 2016 Jun 23; Vol. 59 (12), pp. 5695-705. Date of Electronic Publication: 2016 Jun 06.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic

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Peptidomics for Studying Limited Proteolysis.

• Authors : Tsuchiya T; Department of Molecular Pharmacology, National Cerebral and Cardiovascular Center , Osaka 565-8565, Japan.; Osaki T

Subjects: Proteolysis*; Adrenomedullin/Adrenomedullin/Adrenomedullin/*chemistry ; Extracellular Matrix Proteins/Extracellular Matrix Proteins/Extracellular Matrix Proteins/*chemistry

• Source: Journal of proteome research [J Proteome Res] 2015 Nov 06; Vol. 14 (11), pp. 4921-31. Date of Electronic Publication: 2015 Oct 22.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic

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Picomolar Affinity Antagonist and Sustained Signaling Agonist Peptide Ligands for the Adrenomedullin and Calcitonin Gene-Related Peptide Receptors.

• Authors : Booe, Jason M.; Warner, Margaret L.; Pioszak, Augen A.

• Source: ACS Pharmacology & Translational Science; 8/14/2020, Vol. 3 Issue 4, p759-772, 14p

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N-Glycosylation and Conserved Cysteine Residues in RAMP3 Play a Critical Role for the Functional Expression of CRLR/RAMP3 Adrenomedullin Receptor.

• Authors : Flahaut, Marjorie; Pfister, Corinne; Rossier, Bernard C.

• Source: Biochemistry; 9/2/2003, Vol. 42 Issue 34, p10333-10341, 9p, 1 Diagram, 14 Graphs

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Role of the N-Terminal Domain of the Calcitonin Receptor-like Receptor in Ligand Binding.

• Authors : Chauhan, Madhu¹; Rajarathflam, Krishna¹; Yallampa, Chandra¹

Subjects: *CALCITONIN; *LIGAND binding (Biochemistry); *ADRENOMEDULLIN

• Source: Biochemistry. 1/18/2005, Vol. 44 Issue 2, p782-789. 8p.

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Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin-2 Receptor: Structure-Activity Relationships and Optimization.

• Authors : Zirimwabagabo JO; Department of Chemistry, University of Sheffield, Sheffield S10 2TN, U.K.; Jailani ABA

Subjects: Receptors, Adrenomedullin/Receptors, Adrenomedullin/Receptors, Adrenomedullin/*antagonists & inhibitors ; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/*chemistry ; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/*pharmacology

• Source: Journal of medicinal chemistry [J Med Chem] 2021 Mar 25; Vol. 64 (6), pp. 3299-3319. Date of Electronic Publication: 2021 Mar 05.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic

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Structure and Dynamics of Adrenomedullin Receptors AM 1 and AM 2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.

• Authors : Liang YL; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia.; Belousoff MJ

• Source: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2020 Mar 20; Vol. 3 (2), pp. 263-284. Date of Electronic Publication: 2020 Mar 20 (Print Publication: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection

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Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors.

• Authors : Garelja ML; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; Au M

• Source: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2020 Feb 26; Vol. 3 (2), pp. 246-262. Date of Electronic Publication: 2020 Feb 26 (Print Publication: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection

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Novel Genetic Variant of a Class B G Protein-Coupled Receptor Reveals a Role for Adrenomedullin in Human Fertility.

• Authors : Hay DL; School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, 1010, New Zealand.

• Source: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2018 Sep 21; Vol. 1 (2), pp. 138-139. Date of Electronic Publication: 2018 Sep 21 (Print Publication: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection

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