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Mitoxantrone targets both host and bacteria to overcome vancomycin resistance in Enterococcus faecalis .

• Authors : da Silva RAG; Singapore-MIT Alliance for Research and Technology, Antimicrobial Drug Resistance Interdisciplinary Research Group, Singapore, Singapore.; Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, Singapore, Singapore.

Subjects: Enterococcus faecalis*/Enterococcus faecalis*/Enterococcus faecalis*/genetics ; Vancomycin-Resistant Enterococci*/Vancomycin-Resistant Enterococci*/Vancomycin-Resistant Enterococci*/genetics; Animals

• Source: Science advances [Sci Adv] 2023 Feb 22; Vol. 9 (8), pp. eadd9280. Date of Electronic Publication: 2023 Feb 22.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity.

• Authors : van Groesen, Emma; Mons, Elma; Kotsogianni, Ioli

Subjects: GRAM-positive bacterial infections; BACTERIAL cell walls; METHICILLIN-resistant staphylococcus aureus

• Source: Science Translational Medicine; 8/7/2024, Vol. 16 Issue 759, p1-17, 17p

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An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance.

• Authors : Wu, Kelvin J. Y.; Tresco, Ben I. C.; Ramkissoon, Antonio

• Source: Science; 2/16/2024, Vol. 383 Issue 6684, p721-726, 6p, 5 Diagrams

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Integrating the gut microbiome and pharmacology.

• Authors : Verdegaal, Andrew A.; Goodman, Andrew L.

Subjects: GUT microbiome; PHARMACOLOGY; DRUG bioavailability

• Source: Science Translational Medicine; 1/31/2024, Vol. 16 Issue 732, p1-14, 14p

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Fecal microbiota transplantation promotes reduction of antimicrobial resistance by strain replacement.

• Authors : Woodworth, Michael H.; Conrad, Roth E.; Haldopoulos, Marina

Subjects: FECAL microbiota transplantation; DRUG resistance in microorganisms; MULTIDRUG resistance in bacteria

• Source: Science Translational Medicine; 11/1/2023, Vol. 15 Issue 720, p1-16, 16p

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A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.

• Authors : Blaskovich, Mark A. T.; Hansford, Karl A.; Butler, Mark S.

Subjects: ANTIBIOTICS; GRAM-positive bacterial infections; GLYCOPEPTIDE antibioticsUNITED States

• Source: Science Translational Medicine; 9/14/2022, Vol. 14 Issue 662, p1-16, 16p

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Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance.

• Authors : Zongqiang Wang; Koirala, Bimal; Hernandez, Yozen

• Source: Science; 5/27/2022, Vol. 376 Issue 6596, p991-996, 6p, 4 Diagrams, 1 Chart

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Enterococcal bacteremia in mice is prevented by oral administration of probiotic Bacillus spores.

• Authors : Piewngam, Pipat; Chiou, Janice; Ling, Joie

Subjects: QUORUM sensing; BACTEREMIA; GUT microbiome

• Source: Science Translational Medicine; 11/24/2021, Vol. 13 Issue 621, p1-13, 13p

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Applied Science & Technology Full Text (H.W. Wilson)

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Reduced pannexin 1–IL-33 axis function in donor livers increases risk of MRSA infection in liver transplant recipients.

• Authors : Li, Hao; Yu, Xiaoyu; Shi, Baojie

• Source: Science Translational Medicine; 8/11/2021, Vol. 13 Issue 606, p1-14, 14p

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