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Academic Journal

Toxoplasma gondii macrophage migration inhibitory factor shows anti- Mycobacterium tuberculosis potential via AZIN1/STAT1 interaction.

  • Authors : Yoon C; Department of Molecular and Life Science, Hanyang University, Ansan 15588, South Korea.; Institute of Natural Science & Technology, Hanyang University, Ansan 15588, South Korea.

Subjects: STAT1 Transcription Factor*/STAT1 Transcription Factor*/STAT1 Transcription Factor*/metabolism ; STAT1 Transcription Factor*/STAT1 Transcription Factor*/STAT1 Transcription Factor*/genetics ; Mycobacterium tuberculosis*

  • Source: Science advances [Sci Adv] 2024 Oct 25; Vol. 10 (43), pp. eadq0101. Date of Electronic Publication: 2024 Oct 25.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Academic Journal

Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase.

  • Authors : Swale C; Institute for Advanced Biosciences (IAB), Team Host-Pathogen Interactions and Immunity to Infection, INSERM U1209, CNRS UMR5309, University Grenoble Alpes, Grenoble, France.; Bellini V

Subjects: Cryptosporidiosis* ; Cryptosporidium* ; Malaria, Falciparum*/Malaria, Falciparum*/Malaria, Falciparum*/drug therapy

  • Source: Science translational medicine [Sci Transl Med] 2022 Aug 03; Vol. 14 (656), pp. eabn3231. Date of Electronic Publication: 2022 Aug 03.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication

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Academic Journal

PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.

  • Authors : Fisch D; Host-Toxoplasma Interaction Laboratory, The Francis Crick Institute, London, UK.; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, UK.

Subjects: GTP-Binding Proteins*/GTP-Binding Proteins*/GTP-Binding Proteins*/genetics ; GTP-Binding Proteins*/GTP-Binding Proteins*/GTP-Binding Proteins*/metabolism ; Immunity, Innate*

  • Source: Science (New York, N.Y.) [Science] 2023 Oct 06; Vol. 382 (6666), pp. eadg2253. Date of Electronic Publication: 2023 Oct 06.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Hitching a ride in macrophages.

  • Authors : VanHook AM; Science Signaling, AAAS, Washington, DC 20005, USA. Email: .

Subjects: Toxoplasma* ; Toxoplasmosis*; Humans

  • Source: Science signaling [Sci Signal] 2022 Dec 13; Vol. 15 (764), pp. eadg1743. Date of Electronic Publication: 2022 Dec 13.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication

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Periodical

Closure of U.S. Toxoplasma lab draws ire.

Subjects: Animal Welfare* ; Toxoplasma*; Biomedical Research/Biomedical Research/Biomedical Research/*ethics

  • Source: Science (New York, N.Y.) [Science] 2019 Apr 12; Vol. 364 (6436), pp. 109.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Innate immune cell response to host-parasite interaction in a human intestinal tissue microphysiological system.

  • Authors : Humayun M; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; Ayuso JM

Subjects: Parasites* ; Toxoplasma*; Animals

  • Source: Science advances [Sci Adv] 2022 May 06; Vol. 8 (18), pp. eabm8012. Date of Electronic Publication: 2022 May 06.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Academic Journal

Mitochondria shed their outer membrane in response to infection-induced stress.

  • Authors : Li X; Max Planck Institute for Biology of Ageing, Cologne, Germany.; Straub J

Subjects: Mitochondrial Membranes/Mitochondrial Membranes/Mitochondrial Membranes/*physiology ; Mitochondrial Precursor Protein Import Complex Proteins/Mitochondrial Precursor Protein Import Complex Proteins/Mitochondrial Precursor Protein Import Complex Proteins/*metabolism ; Protozoan Proteins/Protozoan Proteins/Protozoan Proteins/*metabolism

  • Source: Science (New York, N.Y.) [Science] 2022 Jan 14; Vol. 375 (6577), pp. eabi4343. Date of Electronic Publication: 2022 Jan 14.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.

  • Authors : Santos JM; Department of Microbiology, Faculty of Medicine, University of Geneva, 1 rue-Michel Servet, 1211 Geneva 4, Switzerland.; Ferguson DJ

Subjects: Antigens, Protozoan/Antigens, Protozoan/Antigens, Protozoan/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism ; Protozoan Proteins/Protozoan Proteins/Protozoan Proteins/*metabolism

  • Source: Science (New York, N.Y.) [Science] 2011 Jan 28; Vol. 331 (6016), pp. 473-7. Date of Electronic Publication: 2010 Dec 23.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii.

  • Authors : Taylor S; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63130, USA.; Barragan A

Subjects: Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/*metabolism ; Protozoan Proteins/Protozoan Proteins/Protozoan Proteins/*metabolism ; Toxoplasma/Toxoplasma/Toxoplasma/*enzymology

  • Source: Science (New York, N.Y.) [Science] 2006 Dec 15; Vol. 314 (5806), pp. 1776-80.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Back from the dormant stage: second messenger cyclic ADP-ribose essential for Toxoplasma gondii pathogenicity.

  • Authors : Guse AH; The Calcium Signalling Group, Institute of Biochemistry and Molecular Biology I: Cellular Signal Transduction, Centre of Experimental Medicine, University Medical Centre Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

Subjects: Calcium Signaling* ; Gene Expression Regulation*; Calcium/Calcium/Calcium/*metabolism

  • Source: Science signaling [Sci Signal] 2008 Apr 29; Vol. 1 (17), pp. pe18. Date of Electronic Publication: 2008 Apr 29.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication

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