Search Results

tPA-anchored nanorobots for in vivo arterial recanalization at submillimeter-scale segments.

• Authors : Wang B; Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong (CUHK), Sha Tin, N.T., Hong Kong, China.; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, China.

Subjects: Tissue Plasminogen Activator*/Tissue Plasminogen Activator*/Tissue Plasminogen Activator*/therapeutic use ; Arteries*; Animals

• Source: Science advances [Sci Adv] 2024 Feb 02; Vol. 10 (5), pp. eadk8970. Date of Electronic Publication: 2024 Jan 31.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Intracellular tPA-PAI-1 interaction determines VLDL assembly in hepatocytes.

• Authors : Dai W; Versiti Blood Research Institute, Milwaukee, WI 53226, USA.; Zhang H

Subjects: Apolipoproteins B*/Apolipoproteins B*/Apolipoproteins B*/blood ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/blood ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/metabolism

• Source: Science (New York, N.Y.) [Science] 2023 Sep; Vol. 381 (6661), pp. eadh5207. Date of Electronic Publication: 2023 Sep 01.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Fibrinogen-mimicking, multiarm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy.

• Authors : Huang Y; Department of Chemical Engineering, Imperial College London, South Kensington Campus, London, UK.; Gu B

Subjects: Thrombosis*/Thrombosis*/Thrombosis*/drug therapy ; Thrombosis*/Thrombosis*/Thrombosis*/metabolism ; Tissue Plasminogen Activator*/Tissue Plasminogen Activator*/Tissue Plasminogen Activator*/pharmacology

• Source: Science advances [Sci Adv] 2021 Jun 02; Vol. 7 (23). Date of Electronic Publication: 2021 Jun 02 (Print Publication: 2021).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator.

• Authors : Kim YH; National Creative Research Initiative Center for the Study of Central Nervous System Zinc and Department of Neurology, University of Ulsan College of Medicine, 388-1 Poongnap-Dong Songpa-Gu, Seoul 138-736, Korea.; Park JH

Subjects: Cytoprotection*; Neurons/Neurons/Neurons/*cytology ; Neuroprotective Agents/Neuroprotective Agents/Neuroprotective Agents/*pharmacology

• Source: Science (New York, N.Y.) [Science] 1999 Apr 23; Vol. 284 (5414), pp. 647-50.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Converting tissue plasminogen activator to a zymogen: a regulatory triad of Asp-His-Ser.

• Authors : Madison EL; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas 75235.; Kobe A

Subjects: Enzyme Precursors/Enzyme Precursors/Enzyme Precursors/*metabolism ; Tissue Plasminogen Activator/Tissue Plasminogen Activator/Tissue Plasminogen Activator/*metabolism; Amino Acid Sequence

• Source: Science (New York, N.Y.) [Science] 1993 Oct 15; Vol. 262 (5132), pp. 419-21.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning.

• Authors : Seeds NW; Neuroscience Program, University of Colorado Health Sciences Center, Denver 80262, USA.; Williams BL

Subjects: Learning/Learning/Learning/*physiology ; Motor Skills/Motor Skills/Motor Skills/*physiology ; Psychomotor Performance/Psychomotor Performance/Psychomotor Performance/*physiology

• Source: Science (New York, N.Y.) [Science] 1995 Dec 22; Vol. 270 (5244), pp. 1992-4.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Education Full Text (H.W. Wilson)

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Plasmin-resistant PSD-95 inhibitors resolve effect-modifying drug-drug interactions between alteplase and nerinetide in acute stroke.

• Authors : Mayor-Nunez D; NoNO Inc., Toronto, Ontario M5V 1E7, Canada.; Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Subjects: Antifibrinolytic Agents*/Antifibrinolytic Agents*/Antifibrinolytic Agents*/pharmacology ; Brain Ischemia* ; Stroke*/Stroke*/Stroke*/drug therapy

• Source: Science translational medicine [Sci Transl Med] 2021 Apr 07; Vol. 13 (588).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication

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Medicine. Stroke--tPA and the clinic.

• Authors : Marler JR; National Institute of Neurological Disorders and Stroke, Bethesda, MD 20817, USA. ; Goldstein LB

Subjects: Delivery of Health Care*; Brain Ischemia/Brain Ischemia/Brain Ischemia/*drug therapy ; Stroke/Stroke/Stroke/*drug therapy

• Source: Science (New York, N.Y.) [Science] 2003 Sep 19; Vol. 301 (5640), pp. 1677.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Finding new drugs to treat stroke.

• Authors : Barinaga M

Subjects: Brain Ischemia/Brain Ischemia/Brain Ischemia/*drug therapy ; Cerebrovascular Disorders/Cerebrovascular Disorders/Cerebrovascular Disorders/*drug therapy ; Excitatory Amino Acid Antagonists/Excitatory Amino Acid Antagonists/Excitatory Amino Acid Antagonists/*therapeutic use

• Source: Science (New York, N.Y.) [Science] 1996 May 03; Vol. 272 (5262), pp. 664-6.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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