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Academic Journal

Rusting of the lock and key model for protein-ligand binding.

  • Authors : Jorgensen WL; Department of Chemistry, Yale University, New Haven, CT 06511.

Subjects: Cyclosporine*/Cyclosporine*/Cyclosporine*/chemistry ; Tacrolimus*/Tacrolimus*/Tacrolimus*/chemistry; Amino Acid Isomerases/Amino Acid Isomerases/Amino Acid Isomerases/metabolism

  • Source: Science (New York, N.Y.) [Science] 1991 Nov 15; Vol. 254 (5034), pp. 954-5.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Activation of procaspases by FK506 binding protein-mediated oligomerization.

  • Authors : Chang DW; Abramson Family Cancer Research Institute and Department of Cancer Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.; Yang X

Subjects: Caspases/Caspases/Caspases/*metabolism ; Enzyme Precursors/Enzyme Precursors/Enzyme Precursors/*metabolism ; Tacrolimus/Tacrolimus/Tacrolimus/*analogs & derivatives

  • Source: Science's STKE : signal transduction knowledge environment [Sci STKE] 2003 Jan 28; Vol. 2003 (167), pp. PL1. Date of Electronic Publication: 2003 Jan 28.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 100964423 Publication

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Academic Journal

A cell growth switch.

Subjects: Cell Division*; Tacrolimus/Tacrolimus/Tacrolimus/*analogs & derivatives; Animals

  • Source: Science (New York, N.Y.) [Science] 1997 Jun 20; Vol. 276 (5320), pp. 1891.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Controlling signal transduction with synthetic ligands.

Subjects: Signal Transduction*; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Heat-Shock Proteins/Heat-Shock Proteins/Heat-Shock Proteins/*metabolism

  • Source: Science (New York, N.Y.) [Science] 1993 Nov 12; Vol. 262 (5136), pp. 1019-24.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Periodical

Making molecular matches in the cell.

Subjects: Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Heat-Shock Proteins/Heat-Shock Proteins/Heat-Shock Proteins/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism

  • Source: Science (New York, N.Y.) [Science] 1993 Nov 12; Vol. 262 (5136), pp. 989.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Discovering high-affinity ligands for proteins: SAR by NMR.

  • Authors : Shuker SB; Pharmaceutical Discovery Division, Abbott Laboratories, Abbott Park, IL 60064, USA.; Hajduk PJ

Subjects: Ligands* ; Magnetic Resonance Spectroscopy*; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism

  • Source: Science (New York, N.Y.) [Science] 1996 Nov 29; Vol. 274 (5292), pp. 1531-4.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive.

  • Authors : Miyata H; Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.; Satouh Y

Subjects: Calcineurin/Calcineurin/Calcineurin/*physiology ; Calcineurin Inhibitors/Calcineurin Inhibitors/Calcineurin Inhibitors/*pharmacology ; Contraceptive Agents, Male/Contraceptive Agents, Male/Contraceptive Agents, Male/*pharmacology

  • Source: Science (New York, N.Y.) [Science] 2015 Oct 23; Vol. 350 (6259), pp. 442-5. Date of Electronic Publication: 2015 Oct 01.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

DEVELOPMENTAL BIOLOGY. Toward a rapid and reversible male pill.

  • Authors : Castaneda J; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX 77030, USA.; Matzuk MM

Subjects: Calcineurin/Calcineurin/Calcineurin/*physiology ; Calcineurin Inhibitors/Calcineurin Inhibitors/Calcineurin Inhibitors/*pharmacology ; Contraceptive Agents, Male/Contraceptive Agents, Male/Contraceptive Agents, Male/*pharmacology

  • Source: Science (New York, N.Y.) [Science] 2015 Oct 23; Vol. 350 (6259), pp. 385-6. Date of Electronic Publication: 2015 Oct 22.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Prevention of cardiac hypertrophy in mice by calcineurin inhibition.

  • Authors : Sussman MA; Division of Molecular Cardiovascular Biology, Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.; Lim HW

Subjects: Calcineurin Inhibitors* ; Cardiac Myosins* ; Microfilament Proteins*

  • Source: Science (New York, N.Y.) [Science] 1998 Sep 11; Vol. 281 (5383), pp. 1690-3.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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